(ACRV) Acrivon Therapeutics - Ratings and Ratios

Exchange: NASDAQ • Country: United States • Currency: USD • Type: Common Stock • ISIN: US0048901096

ACR-368, ACR-2316, Companion Diagnostics, AP3 Platform

Dividends

Currently no dividends paid
Risk via 5d forecast
Volatility 81.1%
Value at Risk 5%th 113%
Relative Tail Risk -15.18%
Reward TTM
Sharpe Ratio -0.25
Alpha -91.50
CAGR/Max DD -0.44
Character TTM
Hurst Exponent 0.379
Beta 1.745
Beta Downside 2.337
Drawdowns 3y
Max DD 95.47%
Mean DD 69.07%
Median DD 72.78%

Description: ACRV Acrivon Therapeutics December 22, 2025

Acrivon Therapeutics, Inc. (NASDAQ: ACRV) is a clinical-stage biopharma focused on oncology, leveraging its generative phosphoproteomics platform (AP3) to develop drug-specific companion diagnostics (OncoSignature) that match patients to targeted therapies. Its lead candidate, ACR-368, is a selective CHK1/CHK2 inhibitor aimed at endometrial and platinum-resistant ovarian cancers as well as squamous cell carcinomas (e.g., SCCHN, anal cancer). Additional programs include ACR-2316, a dual WEE1/PKMYT1 inhibitor, and a preclinical cell-cycle pipeline built on AP3 and co-crystallography.

As of the latest public filing (Q3 2024), ACRV reported approximately $45 million in cash and marketable securities, giving it roughly 12-month runway at its reported quarterly burn of $15 million. The company raised $50 million in a June 2024 private placement, diluting existing shareholders but extending its cash runway into 2025. Its market capitalization hovers around $150 million, placing it in the lower-mid tier of U.S. biotech peers.

Key sector drivers that could influence ACRV’s valuation include the overall growth of the oncology drug market (projected ~8% CAGR through 2028), increasing payer acceptance of biomarker-driven therapies, and the competitive landscape for CHK1/2 inhibitors, where several larger firms are pursuing similar mechanisms. A successful Phase 2 readout for ACR-368 would be a material catalyst, but the company remains vulnerable to trial delays, regulatory setbacks, and the need for additional financing.

For a deeper, data-focused look at ACRV’s risk-adjusted upside, you might find ValueRay’s analyst toolkit useful.

Piotroski VR‑10 (Strict, 0-10) 0.0

Net Income (-81.8m TTM) > 0 and > 6% of Revenue (6% = 50.9k TTM)
FCFTA -0.47 (>2.0%) and ΔFCFTA -17.14pp (YES ≥ +1.0pp, WARN ≥ +0.5pp)
NWC/Revenue 13.6k% (prev 9244 %; Δ 4372 pp) (YES ≤20% & Δ≤-1pp; WARN ≤25% & Δ≤0 oder ≤40% & Δ≤-3pp)
CFO/TA -0.45 (>3.0%) and CFO -65.8m > Net Income -81.8m (YES >=105%, WARN >=100%)
NO Net Debt/EBITDA fails (EBITDA <= 0)
Current Ratio 8.75 (target 1.5–3.0; WARN 1.2–<1.5 or >3.0–5.0; CFO/TA gate active)
Outstanding Shares last Quarter (38.6m) change vs 12m ago 1.19% (target <= -2.0% for YES)
Gross Margin -43.16% (prev 53.66%; Δ -96.82pp) >=18% & Δ>=+0.5pp (WARN >=15% & Δ>=0)
Asset Turnover 0.47% (prev 0.88%; Δ -0.41pp) >=50% & Δ>=+2pp (WARN >=35% & Δ>=0)
error: Interest Coverage Ratio cannot be calculated (needs EBITDA TTM and Interest Expense TTM)

Altman Z'' -19.66

(A) 0.79 = (Total Current Assets 130.4m - Total Current Liabilities 14.9m) / Total Assets 145.3m
(B) -1.76 = Retained Earnings (Balance) -255.9m / Total Assets 145.3m
warn (B) unusual magnitude: -1.76 — check mapping/units
(C) -0.45 = EBIT TTM -81.8m / Avg Total Assets 180.0m
(D) -15.32 = Book Value of Equity -255.8m / Total Liabilities 16.7m
Total Rating: -19.66 = (6.56 * A) + (3.26 * B) + (6.72 * C) + (1.05 * D)

ValueRay F-Score (Strict, 0-100) 43.15

1. Piotroski 0.0pt
2. FCF Yield 139.9%
3. FCF Margin data missing
4. Debt/Equity 0.02
5. Debt/Ebitda 0.40
6. ROIC - WACC (= -54.41)%
7. RoE -53.71%
8. Rev. Trend 15.09%
9. EPS Trend 42.77%

What is the price of ACRV shares?

As of January 07, 2026, the stock is trading at USD 2.29 with a total of 547,901 shares traded.
Over the past week, the price has changed by -2.97%, over one month by -3.38%, over three months by +19.90% and over the past year by -66.27%.

Is ACRV a buy, sell or hold?

Acrivon Therapeutics has received a consensus analysts rating of 4.33. Therefore, it is recommended to buy ACRV.
  • Strong Buy: 4
  • Buy: 4
  • Hold: 1
  • Sell: 0
  • Strong Sell: 0

What are the forecasts/targets for the ACRV price?

Issuer Target Up/Down from current
Wallstreet Target Price 11.2 387.8%
Analysts Target Price 11.2 387.8%
ValueRay Target Price 2 -11.4%

ACRV Fundamental Data Overview January 04, 2026

Market Cap USD = 77.6m (77.6m USD * 1.0 USD.USD)
P/B = 0.5913
Beta = 1.77
Revenue TTM = 848.0k USD
EBIT TTM = -81.8m USD
EBITDA TTM = -80.5m USD
Long Term Debt = 2.99m USD (from capitalLeaseObligations, last quarter)
Short Term Debt = 1.18m USD (from shortTermDebt, last quarter)
Debt = 2.99m USD (from shortLongTermDebtTotal, last quarter)
Net Debt = -32.4m USD (from netDebt column, last quarter)
Enterprise Value = -48.6m USD (77.6m + Debt 2.99m - CCE 129.3m)
Interest Coverage Ratio = unknown (Ebit TTM -81.8m / Interest Expense TTM 0.0)
FCF Yield = 139.9% (FCF TTM -68.1m / Enterprise Value -48.6m)
FCF Margin = -8027 % (FCF TTM -68.1m / Revenue TTM 848.0k)
Net Margin = -9640 % (Net Income TTM -81.8m / Revenue TTM 848.0k)
Gross Margin = -43.16% ((Revenue TTM 848.0k - Cost of Revenue TTM 1.21m) / Revenue TTM)
Gross Margin QoQ = none% (prev none%)
Tobins Q-Ratio = -0.33 (set to none) (Enterprise Value -48.6m / Total Assets 145.3m)
Interest Expense / Debt = 54.77% (Interest Expense 1.64m / Debt 2.99m)
Taxrate = 21.0% (US default 21%)
NOPAT = -64.6m (EBIT -81.8m * (1 - 21.00%)) [loss with tax shield]
Current Ratio = 8.75 (Total Current Assets 130.4m / Total Current Liabilities 14.9m)
Debt / Equity = 0.02 (Debt 2.99m / totalStockholderEquity, last quarter 128.6m)
Debt / EBITDA = 0.40 (negative EBITDA) (Net Debt -32.4m / EBITDA -80.5m)
Debt / FCF = 0.48 (negative FCF - burning cash) (Net Debt -32.4m / FCF TTM -68.1m)
Total Stockholder Equity = 152.2m (last 4 quarters mean from totalStockholderEquity)
RoA = -56.26% (Net Income -81.8m / Total Assets 145.3m)
RoE = -53.71% (Net Income TTM -81.8m / Total Stockholder Equity 152.2m)
RoCE = -52.68% (EBIT -81.8m / Capital Employed (Equity 152.2m + L.T.Debt 2.99m))
RoIC = -42.43% (negative operating profit) (NOPAT -64.6m / Invested Capital 152.2m)
WACC = 11.98% (E(77.6m)/V(80.6m) * Re(12.44%) + (debt cost/tax rate unavailable))
Discount Rate = 12.44% (= CAPM, Blume Beta Adj.)
Shares Correlation 3-Years: 100.0 | Cagr: 191.5%
Fair Price DCF = unknown (Cash Flow -68.1m)
EPS Correlation: 42.77 | EPS CAGR: 3.16% | SUE: 3.09 | # QB: 4
Revenue Correlation: 15.09 | Revenue CAGR: 0.0% | SUE: 0.0 | # QB: 0
EPS next Quarter (2026-03-31): EPS=-0.49 | Chg30d=+0.172 | Revisions Net=+0 | Analysts=6
EPS next Year (2026-12-31): EPS=-1.91 | Chg30d=+0.374 | Revisions Net=+1 | Growth EPS=+3.1% | Growth Revenue=+802.4%

Additional Sources for ACRV Stock

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Fund Manager Positions: Dataroma | Stockcircle