(ACRV) Acrivon Therapeutics - Ratings and Ratios

Exchange: NASDAQ • Country: United States • Currency: USD • Type: Common Stock • ISIN: US0048901096

Oncology, Inhibitor, Precision, Platform

Risk via 10d forecast
Volatility 99.2%
Value at Risk 5%th 137%
Reward
Sharpe Ratio -0.69
Alpha Jensen -101.65
Character
Hurst Exponent 0.206
Beta 1.837
Drawdowns 3y
Max DD 95.47%
Mean DD 66.35%

Description: ACRV Acrivon Therapeutics October 19, 2025

Acrivon Therapeutics, Inc. (NASDAQ: ACRV) is a clinical-stage biotech focused on oncology drugs that are paired with proprietary companion diagnostics generated through its AP3 (Acrivon Predictive Precision Proteomics) platform. Its lead asset, ACR-368, is a selective CHK1/CHK2 inhibitor being evaluated in endometrial, platinum-resistant ovarian cancers and squamous cell carcinomas such as SCCHN and anal cancer. The pipeline also includes ACR-2316, a dual WEE1/PKMYT1 inhibitor, and a preclinical cell-cycle program derived from AP3 and co-crystallography data.

Key external data points that may influence ACRV’s valuation: (1) As of the latest 10-Q (Q2 2024), the company reported cash and equivalents of roughly $55 million, giving it ~12-month runway under current burn rates-a critical liquidity metric for early-stage biotechs. (2) The global oncology therapeutics market is projected to grow at a CAGR of ~7 % through 2030, driven by rising cancer incidence and expanding precision-medicine adoption, which underpins demand for biomarker-guided agents like ACR-368. (3) Recent sector trends show heightened investor appetite for companies that integrate companion diagnostics early in development, as FDA guidance increasingly favors co-development pathways that can accelerate regulatory review and market access.

If you want a deeper, data-driven assessment of ACRV’s upside potential, ValueRay’s analytical toolkit offers granular financial and scientific metrics that can help you form a more informed view.

ACRV Stock Overview

Market Cap in USD 59m
Sub-Industry Biotechnology
IPO / Inception 2022-11-15
Return 12m vs S&P 500 -78.2%
Analyst Rating 4.33 of 5

ACRV Dividends

Currently no dividends paid

ACRV Growth Ratios

CAGR -50.40%
CAGR/Max DD Calmar Ratio -0.53
CAGR/Mean DD Pain Ratio -0.76
Current Volume 297.4k
Average Volume 323.3k

Piotroski VR‑10 (Strict, 0-10) 0.0

Net Income (-86.0m TTM) > 0 and > 6% of Revenue (6% = 50.9k TTM)
FCFTA -0.46 (>2.0%) and ΔFCFTA -22.19pp (YES ≥ +1.0pp, WARN ≥ +0.5pp)
NWC/Revenue 14.7k% (prev 9080 %; Δ 5658 pp) (YES ≤20% & Δ≤-1pp; WARN ≤25% & Δ≤0 oder ≤40% & Δ≤-3pp)
CFO/TA -0.45 (>3.0%) and CFO -70.8m > Net Income -86.0m (YES >=105%, WARN >=100%)
NO Net Debt/EBITDA fails (EBITDA <= 0)
Current Ratio 10.31 (target 1.5–3.0; WARN 1.2–<1.5 or >3.0–5.0; CFO/TA gate active)
Outstanding Shares last Quarter (38.5m) change vs 12m ago 6.45% (target <= -2.0% for YES)
Gross Margin -57.43% (prev 52.02%; Δ -109.4pp) >=18% & Δ>=+0.5pp (WARN >=15% & Δ>=0)
Asset Turnover 0.44% (prev 0.82%; Δ -0.38pp) >=50% & Δ>=+2pp (WARN >=35% & Δ>=0)
Interest Coverage Ratio -13.61 (EBITDA TTM -91.6m / Interest Expense TTM -6.81m) >= 6 (WARN >= 3)

Altman Z'' -18.96

(A) 0.79 = (Total Current Assets 138.4m - Total Current Liabilities 13.4m) / Total Assets 158.6m
(B) -1.50 = Retained Earnings (Balance) -237.7m / Total Assets 158.6m
warn (B) unusual magnitude: -1.50 — check mapping/units
(C) -0.48 = EBIT TTM -92.8m / Avg Total Assets 194.6m
(D) -15.28 = Book Value of Equity -237.5m / Total Liabilities 15.5m
Total Rating: -18.96 = (6.56 * A) + (3.26 * B) + (6.72 * C) + (1.05 * D)

ValueRay F-Score (Strict, 0-100) 43.99

1. Piotroski 0.0pt = -5.0
2. FCF Yield 97.56% = 5.0
3. FCF Margin data missing
4. Debt/Equity 0.02 = 2.50
5. Debt/Ebitda 0.42 = 2.36
6. ROIC - WACC (= -55.41)% = -12.50
7. RoE -50.78% = -2.50
8. Rev. Trend 11.43% = 0.86
9. EPS Trend 65.36% = 3.27

What is the price of ACRV shares?

As of November 12, 2025, the stock is trading at USD 2.07 with a total of 297,444 shares traded.
Over the past week, the price has changed by -3.72%, over one month by +16.95%, over three months by +68.29% and over the past year by -74.85%.

Is Acrivon Therapeutics a good stock to buy?

No, based on ValueRay´s Fundamental Analyses, Acrivon Therapeutics (NASDAQ:ACRV) is currently (November 2025) a stock to sell. It has a ValueRay Fundamental Rating of 43.99 and therefor a negative outlook according to the companies health.
Based on momentum, paid dividends and discounted-cash-flow analyses, the fair value of ACRV is around 1.50 USD . This means that ACRV is currently overvalued and has a potential downside of -27.54%.

Is ACRV a buy, sell or hold?

Acrivon Therapeutics has received a consensus analysts rating of 4.33. Therefore, it is recommended to buy ACRV.
  • Strong Buy: 4
  • Buy: 4
  • Hold: 1
  • Sell: 0
  • Strong Sell: 0

What are the forecasts/targets for the ACRV price?

Issuer Target Up/Down from current
Wallstreet Target Price 11.2 439.6%
Analysts Target Price 11.2 439.6%
ValueRay Target Price 1.7 -16.9%

ACRV Fundamental Data Overview November 11, 2025

Market Cap USD = 59.1m (59.1m USD * 1.0 USD.USD)
P/B = 0.409
Beta = 1.837
Revenue TTM = 848.0k USD
EBIT TTM = -92.8m USD
EBITDA TTM = -91.6m USD
Long Term Debt = 3.26m USD (from capitalLeaseObligations, last quarter)
Short Term Debt = 2.30m USD (from shortTermDebt, last quarter)
Debt = 3.26m USD (from shortLongTermDebtTotal, last quarter)
Net Debt = -38.6m USD (from netDebt column, last quarter)
Enterprise Value = -75.0m USD (59.1m + Debt 3.26m - CCE 137.4m)
Interest Coverage Ratio = -13.61 (Ebit TTM -92.8m / Interest Expense TTM -6.81m)
FCF Yield = 97.56% (FCF TTM -73.2m / Enterprise Value -75.0m)
FCF Margin = -8631 % (FCF TTM -73.2m / Revenue TTM 848.0k)
Net Margin = -10.1k% (Net Income TTM -86.0m / Revenue TTM 848.0k)
Gross Margin = -57.43% ((Revenue TTM 848.0k - Cost of Revenue TTM 1.33m) / Revenue TTM)
Gross Margin QoQ = none% (prev none%)
Tobins Q-Ratio = -0.47 (set to none) (Enterprise Value -75.0m / Total Assets 158.6m)
Interest Expense / Debt = 50.17% (Interest Expense 1.64m / Debt 3.26m)
Taxrate = 21.0% (US default 21%)
NOPAT = -73.3m (EBIT -92.8m * (1 - 21.00%)) [loss with tax shield]
Current Ratio = 10.31 (Total Current Assets 138.4m / Total Current Liabilities 13.4m)
Debt / Equity = 0.02 (Debt 3.26m / totalStockholderEquity, last quarter 143.0m)
Debt / EBITDA = 0.42 (negative EBITDA) (Net Debt -38.6m / EBITDA -91.6m)
Debt / FCF = 0.53 (negative FCF - burning cash) (Net Debt -38.6m / FCF TTM -73.2m)
Total Stockholder Equity = 169.3m (last 4 quarters mean from totalStockholderEquity)
RoA = -54.20% (Net Income -86.0m / Total Assets 158.6m)
RoE = -50.78% (Net Income TTM -86.0m / Total Stockholder Equity 169.3m)
RoCE = -53.77% (EBIT -92.8m / Capital Employed (Equity 169.3m + L.T.Debt 3.26m))
RoIC = -43.30% (negative operating profit) (NOPAT -73.3m / Invested Capital 169.3m)
WACC = 12.11% (E(59.1m)/V(62.4m) * Re(12.78%) + (debt cost/tax rate unavailable))
Discount Rate = 12.78% (= CAPM, Blume Beta Adj.)
Shares Correlation 3-Years: 100.0 | Cagr: 31.23%
Fair Price DCF = unknown (Cash Flow -73.2m)
EPS Correlation: 65.36 | EPS CAGR: 110.0% | SUE: 4.0 | # QB: 4
Revenue Correlation: 11.43 | Revenue CAGR: 0.0% | SUE: 0.0 | # QB: 0

Additional Sources for ACRV Stock

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Fund Manager Positions: Dataroma | Stockcircle