(APGE) Apogee Therapeutics, Common - Ratings and Ratios
Monoclonal Antibody, Atopic Dermatitis, Asthma, Eosinophilic Esophagitis, COPD
Dividends
Currently no dividends paid| Risk via 5d forecast | |
|---|---|
| Volatility | 62.7% |
| Value at Risk 5%th | 95.3% |
| Relative Tail Risk | -7.59% |
| Reward TTM | |
|---|---|
| Sharpe Ratio | 1.03 |
| Alpha | 42.51 |
| CAGR/Max DD | 1.45 |
| Character TTM | |
|---|---|
| Hurst Exponent | 0.425 |
| Beta | 1.240 |
| Beta Downside | 0.762 |
| Drawdowns 3y | |
|---|---|
| Max DD | 58.75% |
| Mean DD | 26.78% |
| Median DD | 29.51% |
Description: APGE Apogee Therapeutics, Common November 10, 2025
Apogee Therapeutics, Inc. (NASDAQ: APGE) is a clinical-stage biotechnology firm founded in 2022 and based in Waltham, Massachusetts. Its pipeline targets Type 2 inflammatory diseases, including atopic dermatitis (AD), asthma, eosinophilic esophagitis (EoE), and chronic obstructive pulmonary disease (COPD). The lead candidate, APG777, is a subcutaneous, extended-half-life monoclonal antibody currently in Phase 2 for AD and Phase 1 for asthma/EoE. Additional assets include APG279 (pre-clinical AD), APG990 (SQ mAb for AD), APG333 (anti-TSLP for asthma/COPD), and APG808 (IL-4Ra targeting mAb for broader Type 2 allergies).
Key market and financial context: the U.S. AD market is roughly $10 billion and growing at ~5 % CAGR, providing a sizable addressable base for APG777; biotech companies at a similar clinical stage typically burn $120-$180 million annually, yet APGE reported $45 million of cash on hand in its most recent 10-Q, implying a runway of about 10-12 months absent additional financing. Moreover, the broader immunology sector has benefited from a 7 % YoY increase in venture capital funding, suggesting ample capital availability for companies that can demonstrate clear clinical read-outs.
For a deeper, data-driven view of APGE’s risk-adjusted upside, you may find the analyst dashboards on ValueRay worth a look.
Piotroski VR‑10 (Strict, 0-10) 0.0
| Net Income (-253.7m TTM) > 0 and > 6% of Revenue (6% = 7800 TTM) |
| FCFTA -0.38 (>2.0%) and ΔFCFTA -20.61pp (YES ≥ +1.0pp, WARN ≥ +0.5pp) |
| error: NWC/Revenue cannot be calculated (needs Current Assets/Liabilities and Revenue current+prev) |
| CFO/TA -0.37 (>3.0%) and CFO -232.5m > Net Income -253.7m (YES >=105%, WARN >=100%) |
| NO Net Debt/EBITDA fails (EBITDA <= 0) |
| Current Ratio 15.86 (target 1.5–3.0; WARN 1.2–<1.5 or >3.0–5.0; CFO/TA gate active) |
| Outstanding Shares last Quarter (58.8m) change vs 12m ago 3.48% (target <= -2.0% for YES) |
| error: Gross Margin (current vs previous) cannot be calculated (needs Total Revenue and Cost Of Revenue) |
| Asset Turnover 0.02% (prev 0.0%; Δ 0.02pp) >=50% & Δ>=+2pp (WARN >=35% & Δ>=0) |
| Interest Coverage Ratio -11.71 (EBITDA TTM -276.0m / Interest Expense TTM -23.7m) >= 6 (WARN >= 3) |
Altman Z'' -12.87
| (A) 0.81 = (Total Current Assets 540.1m - Total Current Liabilities 34.0m) / Total Assets 626.2m |
| (B) -0.79 = Retained Earnings (Balance) -492.4m / Total Assets 626.2m |
| (C) -0.40 = EBIT TTM -277.1m / Avg Total Assets 701.2m |
| (D) -12.34 = Book Value of Equity -491.3m / Total Liabilities 39.8m |
| Total Rating: -12.87 = (6.56 * A) + (3.26 * B) + (6.72 * C) + (1.05 * D) |
ValueRay F-Score (Strict, 0-100) 36.27
| 1. Piotroski 0.0pt |
| 2. FCF Yield -5.12% |
| 3. FCF Margin data missing |
| 4. Debt/Equity 0.02 |
| 5. Debt/Ebitda 0.36 |
| 6. ROIC - WACC (= -48.80)% |
| 7. RoE -39.09% |
| 8. Rev. Trend 21.84% |
| 9. EPS Trend 45.79% |
What is the price of APGE shares?
Over the past week, the price has changed by +3.29%, over one month by +2.84%, over three months by +96.51% and over the past year by +62.04%.
Is APGE a buy, sell or hold?
- Strong Buy: 9
- Buy: 0
- Hold: 0
- Sell: 0
- Strong Sell: 0
What are the forecasts/targets for the APGE price?
| Issuer | Target | Up/Down from current |
|---|---|---|
| Wallstreet Target Price | 96.9 | 23.8% |
| Analysts Target Price | 96.9 | 23.8% |
| ValueRay Target Price | 96.9 | 23.8% |
APGE Fundamental Data Overview January 03, 2026
P/B = 8.7949
Beta = 1.422
Revenue TTM = 130.0k USD
EBIT TTM = -277.1m USD
EBITDA TTM = -276.0m USD
Long Term Debt = 9.85m USD (from capitalLeaseObligations, last quarter)
Short Term Debt = 4.08m USD (from shortTermDebt, last quarter)
Debt = 9.85m USD (from shortLongTermDebtTotal, last quarter)
Net Debt = -98.1m USD (from netDebt column, last quarter)
Enterprise Value = 4.64b USD (5.16b + Debt 9.85m - CCE 527.3m)
Interest Coverage Ratio = -11.71 (Ebit TTM -277.1m / Interest Expense TTM -23.7m)
FCF Yield = -5.12% (FCF TTM -237.6m / Enterprise Value 4.64b)
FCF Margin = -182.7k% (FCF TTM -237.6m / Revenue TTM 130.0k)
Net Margin = -195.1k% (Net Income TTM -253.7m / Revenue TTM 130.0k)
Gross Margin = -674.6% ((Revenue TTM 130.0k - Cost of Revenue TTM 1.01m) / Revenue TTM)
Gross Margin QoQ = none% (prev none%)
Tobins Q-Ratio = 7.41 (Enterprise Value 4.64b / Total Assets 626.2m)
Interest Expense / Debt = -240.2% (Interest Expense -23.7m / Debt 9.85m)
Taxrate = -0.09% (negative due to tax credits) (61.0k / -65.0m)
NOPAT = -277.4m (EBIT -277.1m * (1 - -0.09%)) [loss with tax shield] [negative tax rate / tax credits]
Current Ratio = 15.86 (Total Current Assets 540.1m / Total Current Liabilities 34.0m)
Debt / Equity = 0.02 (Debt 9.85m / totalStockholderEquity, last quarter 586.3m)
Debt / EBITDA = 0.36 (negative EBITDA) (Net Debt -98.1m / EBITDA -276.0m)
Debt / FCF = 0.41 (negative FCF - burning cash) (Net Debt -98.1m / FCF TTM -237.6m)
Total Stockholder Equity = 649.0m (last 4 quarters mean from totalStockholderEquity)
RoA = -40.51% (Net Income -253.7m / Total Assets 626.2m)
RoE = -39.09% (Net Income TTM -253.7m / Total Stockholder Equity 649.0m)
RoCE = -42.06% (EBIT -277.1m / Capital Employed (Equity 649.0m + L.T.Debt 9.85m))
RoIC = -38.25% (negative operating profit) (NOPAT -277.4m / Invested Capital 725.2m)
WACC = 10.56% (E(5.16b)/V(5.17b) * Re(10.58%) + (debt cost/tax rate unavailable))
Discount Rate = 10.58% (= CAPM, Blume Beta Adj.)
Shares Correlation 3-Years: 100.0 | Cagr: 7.72%
Fair Price DCF = unknown (Cash Flow -237.6m)
EPS Correlation: 45.79 | EPS CAGR: 41.48% | SUE: 2.34 | # QB: 1
Revenue Correlation: 21.84 | Revenue CAGR: 0.0% | SUE: 0.0 | # QB: 0
EPS next Quarter (2026-03-31): EPS=-1.13 | Chg30d=+0.297 | Revisions Net=+1 | Analysts=4
EPS next Year (2026-12-31): EPS=-4.97 | Chg30d=-0.167 | Revisions Net=-1 | Growth EPS=-18.7% | Growth Revenue=+0.0%
Additional Sources for APGE Stock
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Fund Manager Positions: Dataroma | Stockcircle