(APLS) Apellis Pharmaceuticals - Ratings and Ratios

Exchange: NASDAQ • Country: United States • Currency: USD • Type: Common Stock • ISIN: US03753U1060

Empaveli, Syfovre, Therapeutic Compounds, Biopharmaceuticals

APLS EPS (Earnings per Share)

EPS (Earnings per Share) of APLS over the last years for every Quarter: "2020-03": -2.29, "2020-06": -1.57, "2020-09": -1.79, "2020-12": 0.99, "2021-03": -2.32, "2021-06": -2.72, "2021-09": -2.28, "2021-12": -1.73, "2022-03": -1.42, "2022-06": -1.46, "2022-09": -1.75, "2022-12": -1.5, "2023-03": -1.56, "2023-06": -1.02, "2023-09": -1.17, "2023-12": -0.73, "2024-03": -0.54, "2024-06": -0.3, "2024-09": -0.46, "2024-12": -0.29, "2025-03": -0.74,

APLS Revenue

Revenue of APLS over the last years for every Quarter: 2020-03: 0, 2020-06: 0, 2020-09: 0.646, 2020-12: 250, 2021-03: 0, 2021-06: 0.623, 2021-09: 5.65, 2021-12: 60.29, 2022-03: 14.381, 2022-06: 16.322, 2022-09: 22.056, 2022-12: 22.663, 2023-03: 44.846, 2023-06: 94.969, 2023-09: 110.399, 2023-12: 146.377, 2024-03: 172.325, 2024-06: 199.685, 2024-09: 196.83, 2024-12: 212.528, 2025-03: 166.797,

Description: APLS Apellis Pharmaceuticals

Apellis Pharmaceuticals, Inc. is a commercial-stage biopharmaceutical company that focuses on developing novel therapeutics for high unmet medical needs, with a particular emphasis on complement-driven diseases. The companys product portfolio includes EMPAVELI, a treatment for paroxysmal nocturnal hemoglobinuria, and SYFOVRE, a treatment for geographic atrophy secondary to age-related macular degeneration. Apellis is also exploring the potential of EMPAVELI in various other indications, including C3 glomerulopathy, hematopoietic stem cell transplantation-associated thrombotic microangiopathy, and focal segmental glomerulosclerosis.

The companys pipeline is bolstered by strategic collaborations, including a partnership with Swedish Orphan Biovitrum AB for the development and commercialization of pegcetacoplan, and a collaboration with Beam Therapeutics Inc. to leverage base editing technology for the discovery of new treatments for complement-driven diseases. Additionally, Apellis is developing APL-3007, a small interfering RNA (siRNA) therapy for the treatment of geographic atrophy.

From a technical analysis perspective, APLS stock is currently trading at $19.26, above its 20-day and 50-day simple moving averages (SMA) of $18.15 and $18.54, respectively. However, the stock remains below its 200-day SMA of $27.17, indicating a potential long-term downtrend. The average true range (ATR) of 1.01 represents a 5.26% daily price movement, suggesting moderate volatility. Given the current technical setup, a potential trading opportunity may arise if the stock breaks above its 200-day SMA, potentially targeting the 52-week high of $42.56.

Fundamentally, Apellis has a market capitalization of $2.4 billion, with a negative return on equity (ROE) of -100.06%, indicating significant investment in research and development. The absence of a price-to-earnings (P/E) ratio is expected, given the companys current lack of profitability. However, as the company continues to advance its pipeline and commercialize its existing products, investors may expect improved financial performance in the future. Based on the current fundamental and technical data, a potential forecast for APLS stock could involve a gradual increase in value as the company achieves key milestones, potentially reaching $25-$30 in the next 6-12 months, driven by the success of its existing products and pipeline advancements.

Additional Sources for APLS Stock

News: Wall Street Journal | Benzinga | Yahoo Finance
Tweets: X | Stocktwits
Fund Manager Positions: Dataroma | Stockcircle

APLS Stock Overview

Market Cap in USD 2,240m
Sector Healthcare
Industry Biotechnology
GiC Sub-Industry Biotechnology
IPO / Inception 2017-11-09

APLS Stock Ratings

Growth Rating -46.8
Fundamental -25.7
Dividend Rating 0.0
Rel. Strength -45.8
Analysts 4.09 of 5
Fair Price Momentum 14.20 USD
Fair Price DCF -

APLS Dividends

Currently no dividends paid

APLS Growth Ratios

Growth Correlation 3m -23.9%
Growth Correlation 12m -88%
Growth Correlation 5y -22.7%
CAGR 5y -9.93%
CAGR/Max DD 5y -0.12
Sharpe Ratio 12m -1.17
Alpha -62.64
Beta 0.943
Volatility 61.53%
Current Volume 891.1k
Average Volume 20d 1807.8k
What is the price of APLS shares?
As of July 06, 2025, the stock is trading at USD 18.26 with a total of 891,120 shares traded.
Over the past week, the price has changed by +4.76%, over one month by -1.35%, over three months by -8.56% and over the past year by -49.61%.
Is Apellis Pharmaceuticals a good stock to buy?
Probably not. Based on ValueRay´s Fundamental Analyses, Apellis Pharmaceuticals (NASDAQ:APLS) is currently (July 2025) not a good stock to buy. It has a ValueRay Fundamental Rating of -25.72 and therefor a somewhat negative outlook according to the companies health.
Based on momentum, paid dividends and discounted-cash-flow analyses, the fair value of APLS is around 14.20 USD . This means that APLS is currently overvalued and has a potential downside of -22.23%.
Is APLS a buy, sell or hold?
Apellis Pharmaceuticals has received a consensus analysts rating of 4.09. Therefore, it is recommended to buy APLS.
  • Strong Buy: 10
  • Buy: 4
  • Hold: 8
  • Sell: 0
  • Strong Sell: 0
What are the forecasts for APLS share price target?
According to our own proprietary Forecast Model, APLS Apellis Pharmaceuticals will be worth about 16.3 in July 2026. The stock is currently trading at 18.26. This means that the stock has a potential downside of -10.51%.
Issuer Target Up/Down from current
Wallstreet Target Price 35.4 93.6%
Analysts Target Price 36.3 98.5%
ValueRay Target Price 16.3 -10.5%