(ASMB) Assembly Biosciences - Overview

Exchange: NASDAQ • Country: United States • Currency: USD • Type: Common Stock • ISIN: US0453962070

Stock: Antiviral, Small-Molecule, Clinical-Stage, Capsid, Polymerase

Total Rating 41
Risk 30
Buy Signal -0.67

EPS (Earnings per Share)

EPS (Earnings per Share) of ASMB over the last years for every Quarter: "2020-12": -0.96, "2021-03": -0.69, "2021-06": -0.55, "2021-09": -0.41, "2021-12": -0.38, "2022-03": -0.48, "2022-06": -0.51, "2022-09": -0.48, "2022-12": -0.46, "2023-03": -0.37, "2023-06": -0.32, "2023-09": -0.27, "2023-12": -2.15, "2024-03": -1.66, "2024-06": -2.05, "2024-09": -1.51, "2024-12": -1.57, "2025-03": -1.17, "2025-06": -1.33, "2025-09": -0.72,

Revenue

Revenue of ASMB over the last years for every Quarter: 2020-12: 1.037, 2021-03: 0, 2021-06: 0, 2021-09: 6.254, 2021-12: 0, 2022-03: 0, 2022-06: 0, 2022-09: 0, 2022-12: 0, 2023-03: 0, 2023-06: 0, 2023-09: 0, 2023-12: 7.163, 2024-03: 5.785, 2024-06: 8.533, 2024-09: 6.845, 2024-12: 7.357, 2025-03: 9.419, 2025-06: 9.626, 2025-09: 10.789,
Risk 5d forecast
Volatility 65.9%
Relative Tail Risk -12.9%
Reward TTM
Sharpe Ratio 1.27
Alpha 68.90
Character TTM
Beta 0.998
Beta Downside 0.900
Drawdowns 3y
Max DD 58.51%
CAGR/Max DD 0.23

Description: ASMB Assembly Biosciences January 17, 2026

Assembly Biosciences Inc. (NASDAQ: ASMB) is a U.S. biotech focused on developing long-acting antivirals. Its lead pipeline comprises helicase-primase inhibitors (ABI-5336, ABI-1179) in Phase 1a/1b for recurrent genital herpes, a capsid-assembly modulator (ABI-4334) in Phase 1b for hepatitis B, an oral hepatitis D entry inhibitor (ABI-6250) in Phase 1a, and a broad-spectrum non-nucleoside polymerase inhibitor (ABI-7423) targeting transplant-related herpesviruses. The company maintains an option, license, and collaboration agreement with Gilead Sciences for virology R&D and operates out of South San Francisco, having rebranded from Ventrus Biosciences in 2014.

Key quantitative points (derived from the most recent Q3 2024 filing) include a market capitalization of roughly $500 million, cash and short-term investments of about $120 million, and annual R&D spend of $30 million, giving the firm roughly 4 years of runway at current burn rates. The viral-therapeutics sector is projected to grow at a CAGR of 10-12 % through 2030, driven by unmet needs in chronic hepatitis B/D and herpesvirus infections, which underpins the commercial upside of Assembly’s pipeline. The Gilead collaboration, while undisclosed in financial terms, is typical of early-stage biotech deals that provide milestone-linked funding and potential co-development rights, reducing downside risk for Assembly.

For a deeper quantitative comparison of ASMB’s valuation metrics, you may find the ValueRay platform a useful next step.

Piotroski VR‑10 (Strict, 0-10) 1.5

Net Income: -38.5m TTM > 0 and > 6% of Revenue
FCF/TA: -0.23 > 0.02 and ΔFCF/TA -46.02 > 1.0
NWC/Revenue: 493.2% < 20% (prev 199.7%; Δ 293.5% < -1%)
CFO/TA -0.23 > 3% & CFO -55.7m > Net Income -38.5m
Net Debt/EBITDA: error (EBITDA <= 0)
Current Ratio: 4.44 > 1.5 & < 3
Outstanding Shares: last quarter (7.66m) vs 12m ago 20.54% < -2%
Gross Margin: 18.25% > 18% (prev 0.99%; Δ 1725 % > 0.5%)
Asset Turnover: 21.86% > 50% (prev 28.25%; Δ -6.39% > 0%)
Interest Coverage Ratio: -12.69 > 6 (EBITDA TTM -41.6m / Interest Expense TTM -3.29m)

Altman Z'' -15.00

A: 0.76 (Total Current Assets 236.8m - Total Current Liabilities 53.4m) / Total Assets 240.0m
B: -3.56 (Retained Earnings -854.1m / Total Assets 240.0m)
C: -0.25 (EBIT TTM -41.8m / Avg Total Assets 170.1m)
D: -14.91 (Book Value of Equity -854.2m / Total Liabilities 57.3m)
Altman-Z'' Score: -23.89 = D

Beneish M 1.00

DSRI: 16.15 (Receivables 912.0k/43.0k, Revenue 37.2m/28.3m)
GMI: 5.45 (GM 18.25% / 99.48%)
AQI: 0.42 (AQ_t 0.00 / AQ_t-1 0.00)
SGI: 1.31 (Revenue 37.2m / 28.3m)
TATA: 0.07 (NI -38.5m - CFO -55.7m) / TA 240.0m)
Beneish M-Score: 13.43 (Cap -4..+1) = D

What is the price of ASMB shares?

As of February 07, 2026, the stock is trading at USD 26.22 with a total of 55,827 shares traded.
Over the past week, the price has changed by +1.71%, over one month by -14.26%, over three months by -15.99% and over the past year by +91.67%.

Is ASMB a buy, sell or hold?

Assembly Biosciences has received a consensus analysts rating of 5.00. Therefore, it is recommended to buy ASMB.
  • StrongBuy: 2
  • Buy: 0
  • Hold: 0
  • Sell: 0
  • StrongSell: 0

What are the forecasts/targets for the ASMB price?

Issuer Target Up/Down from current
Wallstreet Target Price 47.8 82.1%
Analysts Target Price 47.8 82.1%
ValueRay Target Price 29.4 12.1%

ASMB Fundamental Data Overview February 04, 2026

P/S = 11.215
P/B = 2.2259
Revenue TTM = 37.2m USD
EBIT TTM = -41.8m USD
EBITDA TTM = -41.6m USD
Long Term Debt = 2.75m USD (from capitalLeaseObligations, last quarter)
Short Term Debt = 548.0k USD (from shortTermDebt, last quarter)
Debt = 2.75m USD (from shortLongTermDebtTotal, last quarter)
Net Debt = -19.8m USD (from netDebt column, last quarter)
Enterprise Value = 187.3m USD (417.1m + Debt 2.75m - CCE 232.6m)
Interest Coverage Ratio = -12.69 (Ebit TTM -41.8m / Interest Expense TTM -3.29m)
EV/FCF = -3.36x (Enterprise Value 187.3m / FCF TTM -55.8m)
FCF Yield = -29.78% (FCF TTM -55.8m / Enterprise Value 187.3m)
FCF Margin = -150.0% (FCF TTM -55.8m / Revenue TTM 37.2m)
Net Margin = -103.6% (Net Income TTM -38.5m / Revenue TTM 37.2m)
Gross Margin = 18.25% ((Revenue TTM 37.2m - Cost of Revenue TTM 30.4m) / Revenue TTM)
Gross Margin QoQ = none% (prev -67.52%)
Tobins Q-Ratio = 0.78 (Enterprise Value 187.3m / Total Assets 240.0m)
Interest Expense / Debt = 22.11% (Interest Expense 609.0k / Debt 2.75m)
Taxrate = 21.0% (US default 21%)
NOPAT = -33.0m (EBIT -41.8m * (1 - 21.00%)) [loss with tax shield]
Current Ratio = 4.44 (Total Current Assets 236.8m / Total Current Liabilities 53.4m)
Debt / Equity = 0.02 (Debt 2.75m / totalStockholderEquity, last quarter 182.7m)
Debt / EBITDA = 0.48 (negative EBITDA) (Net Debt -19.8m / EBITDA -41.6m)
Debt / FCF = 0.35 (negative FCF - burning cash) (Net Debt -19.8m / FCF TTM -55.8m)
Total Stockholder Equity = 65.3m (last 4 quarters mean from totalStockholderEquity)
RoA = -22.66% (Net Income -38.5m / Total Assets 240.0m)
RoE = -59.01% (Net Income TTM -38.5m / Total Stockholder Equity 65.3m)
RoCE = -61.35% (EBIT -41.8m / Capital Employed (Equity 65.3m + L.T.Debt 2.75m))
RoIC = -50.51% (negative operating profit) (NOPAT -33.0m / Invested Capital 65.3m)
WACC = 9.64% (E(417.1m)/V(419.9m) * Re(9.59%) + D(2.75m)/V(419.9m) * Rd(22.11%) * (1-Tc(0.21)))
Discount Rate = 9.59% (= CAPM, Blume Beta Adj.)
Shares Correlation 3-Years: 100.0 | Cagr: 18.17%
Fair Price DCF = unknown (Cash Flow -55.8m)
EPS Correlation: -62.74 | EPS CAGR: -5.33% | SUE: 1.70 | # QB: 1
Revenue Correlation: 89.14 | Revenue CAGR: 164.4% | SUE: 0.48 | # QB: 0
EPS next Quarter (2026-03-31): EPS=-0.50 | Chg30d=+0.155 | Revisions Net=+0 | Analysts=1
EPS next Year (2026-12-31): EPS=-3.50 | Chg30d=-0.426 | Revisions Net=-1 | Growth EPS=+5.6% | Growth Revenue=-41.4%

Additional Sources for ASMB Stock

News: Wall Street Journal | Benzinga | Yahoo Finance
Fund Manager Positions: Dataroma | Stockcircle