(CMPX) Compass Therapeutics - Overview

Exchange: NASDAQ • Country: United States • Currency: USD • Type: Common Stock • ISIN: US20454B1044

Stock: Trocimig, CTX-471, CTX-8371, CTX-10726

Total Rating 51
Risk 67
Buy Signal 0.36

EPS (Earnings per Share)

EPS (Earnings per Share) of CMPX over the last years for every Quarter: "2020-12": -0.16, "2021-03": -0.14, "2021-06": -1.07, "2021-09": -0.1, "2021-12": -0.21, "2022-03": -0.07, "2022-06": -0.08, "2022-09": -0.12, "2022-12": -0.1, "2023-03": -0.06, "2023-06": -0.09, "2023-09": -0.08, "2023-12": -0.11, "2024-03": -0.08, "2024-06": -0.1, "2024-09": -0.08, "2024-12": -0.11, "2025-03": -0.12, "2025-06": -0.14, "2025-09": -0.08, "2025-12": 0,

Revenue

Revenue of CMPX over the last years for every Quarter: 2020-12: 0, 2021-03: 0, 2021-06: 0, 2021-09: 0, 2021-12: 0, 2022-03: 0, 2022-06: 0, 2022-09: 0, 2022-12: 0, 2023-03: 0, 2023-06: 0, 2023-09: 0, 2023-12: 2.844, 2024-03: 0, 2024-06: 0.85, 2024-09: 0, 2024-12: 0, 2025-03: 0, 2025-06: 0, 2025-09: 0, 2025-12: null,
Risk 5d forecast
Volatility 74.4%
Relative Tail Risk -6.49%
Reward TTM
Sharpe Ratio 1.14
Alpha 75.21
Character TTM
Beta 1.177
Beta Downside 1.560
Drawdowns 3y
Max DD 79.90%
CAGR/Max DD 0.25

Description: CMPX Compass Therapeutics December 29, 2025

Compass Therapeutics (NASDAQ:CMPX) is a Boston-based, clinical-stage biotech that concentrates on antibody-based oncology therapies. Its lead candidates are tove-cimig, a DLL4/VEGF-A bispecific designed to shut down tumor angiogenesis; CTX-471, an IgG4 agonist of the T-cell co-stimulatory receptor CD137; and CTX-8371, a PD-1/PD-L1 bispecific checkpoint inhibitor. The company also maintains a broader pipeline of bispecifics targeting VEGF-A, PD-1 and other immune-modulatory pathways.

Key operational metrics (Q2 2025 filing) show ~ $68 million in cash and equivalents, a net loss of $22 million for the quarter, and an R&D spend of $15 million, reflecting its heavy investment in early-stage trials. The oncology biotech sector is benefiting from a projected $200 billion global market for bispecific antibodies by 2030, while recent FDA approvals of similar agents (e.g., tebentafusp, amivantamab) have accelerated investor interest and partnership opportunities. Compass recently entered a research collaboration with a major pharma partner to co-develop its VEGF-IO bispecific platform, potentially de-risking later-stage development and providing non-dilutive funding.

For a deeper, data-driven view of CMPX’s valuation dynamics, you might explore the analyst dashboards on ValueRay.

Piotroski VR‑10 (Strict, 0-10) 1.0

Net Income: -65.8m TTM > 0 and > 6% of Revenue
FCF/TA: -0.19 > 0.02 and ΔFCF/TA 12.76 > 1.0
NWC/Revenue: 24.6k% < 20% (prev 3701 %; Δ 20.9k% < -1%)
CFO/TA -0.19 > 3% & CFO -45.1m > Net Income -65.8m
Net Debt/EBITDA: error (EBITDA <= 0)
Current Ratio: 17.82 > 1.5 & < 3
Outstanding Shares: last quarter (138.3m) vs 12m ago 0.50% < -2%
Gross Margin: 56.82% > 18% (prev 0.75%; Δ 5608 % > 0.5%)
Asset Turnover: 0.45% > 50% (prev 2.48%; Δ -2.03% > 0%)
Interest Coverage Ratio: -17.21 > 6 (EBITDA TTM -68.8m / Interest Expense TTM -4.06m)

Altman Z'' -15.00

A: 0.90 (Total Current Assets 221.1m - Total Current Liabilities 12.4m) / Total Assets 231.3m
B: -1.80 (Retained Earnings -415.5m / Total Assets 231.3m)
C: -0.37 (EBIT TTM -69.9m / Avg Total Assets 190.2m)
D: -19.18 (Book Value of Equity -415.1m / Total Liabilities 21.6m)
Altman-Z'' Score: -22.54 = D

What is the price of CMPX shares?

As of February 07, 2026, the stock is trading at USD 6.52 with a total of 2,008,084 shares traded.
Over the past week, the price has changed by +1.87%, over one month by +32.79%, over three months by +63.00% and over the past year by +86.29%.

Is CMPX a buy, sell or hold?

Compass Therapeutics has received a consensus analysts rating of 4.78. Therefore, it is recommended to buy CMPX.
  • StrongBuy: 7
  • Buy: 2
  • Hold: 0
  • Sell: 0
  • StrongSell: 0

What are the forecasts/targets for the CMPX price?

Issuer Target Up/Down from current
Wallstreet Target Price 13.2 102.9%
Analysts Target Price 13.2 102.9%
ValueRay Target Price 7.3 11.8%

CMPX Fundamental Data Overview February 03, 2026

P/S = 439.2487
P/B = 5.4136
Revenue TTM = 850.0k USD
EBIT TTM = -69.9m USD
EBITDA TTM = -68.8m USD
Long Term Debt = 9.87m USD (from capitalLeaseObligations, last quarter)
Short Term Debt = 633.0k USD (from shortTermDebt, last quarter)
Debt = 9.87m USD (from shortLongTermDebtTotal, last quarter)
Net Debt = -36.3m USD (from netDebt column, last quarter)
Enterprise Value = 928.3m USD (1.14b + Debt 9.87m - CCE 219.9m)
Interest Coverage Ratio = -17.21 (Ebit TTM -69.9m / Interest Expense TTM -4.06m)
EV/FCF = -20.59x (Enterprise Value 928.3m / FCF TTM -45.1m)
FCF Yield = -4.86% (FCF TTM -45.1m / Enterprise Value 928.3m)
FCF Margin = -5303 % (FCF TTM -45.1m / Revenue TTM 850.0k)
Net Margin = -7742 % (Net Income TTM -65.8m / Revenue TTM 850.0k)
Gross Margin = 56.82% ((Revenue TTM 850.0k - Cost of Revenue TTM 367.0k) / Revenue TTM)
Gross Margin QoQ = none% (prev none%)
Tobins Q-Ratio = 4.01 (Enterprise Value 928.3m / Total Assets 231.3m)
Interest Expense / Debt = 18.99% (Interest Expense 1.87m / Debt 9.87m)
Taxrate = 21.0% (US default 21%)
NOPAT = -55.2m (EBIT -69.9m * (1 - 21.00%)) [loss with tax shield]
Current Ratio = 17.82 (Total Current Assets 221.1m / Total Current Liabilities 12.4m)
Debt / Equity = 0.05 (Debt 9.87m / totalStockholderEquity, last quarter 209.6m)
Debt / EBITDA = 0.53 (negative EBITDA) (Net Debt -36.3m / EBITDA -68.8m)
Debt / FCF = 0.81 (negative FCF - burning cash) (Net Debt -36.3m / FCF TTM -45.1m)
Total Stockholder Equity = 134.6m (last 4 quarters mean from totalStockholderEquity)
RoA = -34.60% (Net Income -65.8m / Total Assets 231.3m)
RoE = -48.90% (Net Income TTM -65.8m / Total Stockholder Equity 134.6m)
RoCE = -48.37% (EBIT -69.9m / Capital Employed (Equity 134.6m + L.T.Debt 9.87m))
RoIC = -41.01% (negative operating profit) (NOPAT -55.2m / Invested Capital 134.6m)
WACC = 10.29% (E(1.14b)/V(1.15b) * Re(10.25%) + D(9.87m)/V(1.15b) * Rd(18.99%) * (1-Tc(0.21)))
Discount Rate = 10.25% (= CAPM, Blume Beta Adj.)
Shares Correlation 3-Years: 100.0 | Cagr: 4.07%
Fair Price DCF = unknown (Cash Flow -45.1m)
EPS Correlation: 7.14 | EPS CAGR: 18.53% | SUE: 3.18 | # QB: 2
Revenue Correlation: 8.37 | Revenue CAGR: 0.0% | SUE: 0.0 | # QB: 0
EPS next Quarter (2026-03-31): EPS=-0.10 | Chg30d=+0.003 | Revisions Net=+1 | Analysts=8
EPS next Year (2026-12-31): EPS=-0.41 | Chg30d=+0.005 | Revisions Net=+1 | Growth EPS=+1.0% | Growth Revenue=+0.0%

Additional Sources for CMPX Stock

News: Wall Street Journal | Benzinga | Yahoo Finance
Fund Manager Positions: Dataroma | Stockcircle