(CNTA) Centessa Pharmaceuticals - Ratings and Ratios

Exchange: NASDAQ • Country: United Kingdom • Currency: USD • Type: Common Stock • ISIN: US1523091007

Serpin, OXER1, Vasopressin, Platelet, Kidney

Description: CNTA Centessa Pharmaceuticals August 09, 2025

Centessa Pharmaceuticals PLC ADR (NASDAQ:CNTA) is a biotechnology company listed on the NASDAQ stock exchange, originating from the United Kingdom. The companys stock is classified under the GICS Sub Industry of Biotechnology.

The stocks recent performance indicates a market capitalization of approximately $2.15 billion USD, with an average trading volume of over 1 million shares. The absence of a Price-to-Earnings (P/E) ratio, both current and forward, suggests that the company is currently unprofitable, which is not uncommon for companies in the biotechnology sector, particularly those focused on research and development.

A key driver for CNTAs stock performance will be its ability to progress through clinical trials and obtain regulatory approvals for its drug candidates. The Return on Equity (RoE) of -65.75% underscores the significant investment in research and development, highlighting the companys growth stage and the inherent risks associated with the biotechnology industry.

From a trading perspective, the stocks beta of 1.485 indicates a higher volatility compared to the overall market, suggesting that investors should be prepared for potentially significant price swings. The stocks current price is near its 52-week high, having more than doubled from its 52-week low, indicating a strong recent performance.

To evaluate the investment potential of CNTA, key performance indicators (KPIs) to monitor include the progress of its pipeline assets, cash burn rate, and any upcoming milestones such as clinical trial results or regulatory decisions. Economic drivers influencing the stocks performance will include overall market sentiment towards biotechnology stocks, interest rate changes affecting the cost of capital, and broader healthcare industry trends.

CNTA Stock Overview

Market Cap in USD 3,237m
Sub-Industry Biotechnology
IPO / Inception 2021-05-28

CNTA Stock Ratings

Growth Rating 55.3%
Fundamental 32.9%
Dividend Rating -
Return 12m vs S&P 500 31.7%
Analyst Rating 4.64 of 5

CNTA Dividends

Currently no dividends paid

CNTA Growth Ratios

Growth Correlation 3m 79.2%
Growth Correlation 12m 16.5%
Growth Correlation 5y 27.8%
CAGR 5y 83.11%
CAGR/Max DD 3y (Calmar Ratio) 1.90
CAGR/Mean DD 3y (Pain Ratio) 5.89
Sharpe Ratio 12m 0.20
Alpha 31.06
Beta 1.573
Volatility 62.96%
Current Volume 316.3k
Average Volume 20d 964.4k
Stop Loss 22.9 (-5.2%)
Signal 0.18

Piotroski VR‑10 (Strict, 0-10) 1.0

Net Income (-230.4m TTM) > 0 and > 6% of Revenue (6% = 957.1k TTM)
FCFTA -0.29 (>2.0%) and ΔFCFTA 6.61pp (YES ≥ +1.0pp, WARN ≥ +0.5pp)
NWC/Revenue 1697 % (prev 4755 %; Δ -3059 pp) (YES ≤20% & Δ≤-1pp; WARN ≤25% & Δ≤0 oder ≤40% & Δ≤-3pp)
CFO/TA -0.29 (>3.0%) and CFO -143.9m > Net Income -230.4m (YES >=105%, WARN >=100%)
NO Net Debt/EBITDA fails (EBITDA <= 0)
Current Ratio 10.12 (target 1.5–3.0; WARN 1.2–<1.5 or >3.0–5.0; CFO/TA gate active)
Outstanding Shares last Quarter (133.7m) change vs 12m ago 22.09% (target <= -2.0% for YES)
Gross Margin 92.72% (prev 86.10%; Δ 6.62pp) >=18% & Δ>=+0.5pp (WARN >=15% & Δ>=0)
Asset Turnover 3.58% (prev 1.73%; Δ 1.85pp) >=50% & Δ>=+2pp (WARN >=35% & Δ>=0)
Interest Coverage Ratio -19.93 (EBITDA TTM -214.2m / Interest Expense TTM 10.8m) >= 6 (WARN >= 3)

Altman Z'' -14.28

(A) 0.55 = (Total Current Assets 300.4m - Total Current Liabilities 29.7m) / Total Assets 492.1m
(B) -2.16 = Retained Earnings (Balance) -1.07b / Total Assets 492.1m
warn (B) unusual magnitude: -2.16 — check mapping/units
(C) -0.48 = EBIT TTM -215.1m / Avg Total Assets 445.5m
(D) -7.22 = Book Value of Equity -1.06b / Total Liabilities 147.2m
Total Rating: -14.28 = (6.56 * A) + (3.26 * B) + (6.72 * C) + (1.05 * D)

ValueRay F-Score (Strict, 0-100) 32.94

1. Piotroski 1.0pt = -4.0
2. FCF Yield -4.64% = -2.32
3. FCF Margin data missing
4. Debt/Equity 0.34 = 2.44
5. Debt/Ebitda -0.34 = -2.50
6. ROIC - WACC (= -54.43)% = -12.50
7. RoE -56.47% = -2.50
8. Rev. Trend 36.29% = 2.72
9. EPS Trend 31.97% = 1.60

What is the price of CNTA shares?

As of October 26, 2025, the stock is trading at USD 24.15 with a total of 316,325 shares traded.
Over the past week, the price has changed by +4.91%, over one month by +0.75%, over three months by +56.01% and over the past year by +55.81%.

Is Centessa Pharmaceuticals a good stock to buy?

No, based on ValueRay´s Fundamental Analyses, Centessa Pharmaceuticals (NASDAQ:CNTA) is currently (October 2025) a stock to sell. It has a ValueRay Fundamental Rating of 32.94 and therefor a negative outlook according to the companies health.
Based on momentum, paid dividends and discounted-cash-flow analyses, the fair value of CNTA is around 24.91 USD . This means that CNTA is currently overvalued and has a potential downside of 3.15%.

Is CNTA a buy, sell or hold?

Centessa Pharmaceuticals has received a consensus analysts rating of 4.64. Therefore, it is recommended to buy CNTA.
  • Strong Buy: 7
  • Buy: 4
  • Hold: 0
  • Sell: 0
  • Strong Sell: 0

What are the forecasts/targets for the CNTA price?

Issuer Target Up/Down from current
Wallstreet Target Price 32.5 34.4%
Analysts Target Price 32.5 34.4%
ValueRay Target Price 28.5 18.1%

CNTA Fundamental Data Overview October 25, 2025

Market Cap USD = 3.24b (3.24b USD * 1.0 USD.USD)
P/S = 215.7688
P/B = 8.9598
Beta = 1.573
Revenue TTM = 16.0m USD
EBIT TTM = -215.1m USD
EBITDA TTM = -214.2m USD
Long Term Debt = 109.5m USD (from longTermDebt, last quarter)
Short Term Debt = 1.31m USD (from shortTermDebt, last quarter)
Debt = 118.1m USD (from shortLongTermDebtTotal, last quarter)
Net Debt = 73.9m USD (from netDebt column, last quarter)
Enterprise Value = 3.10b USD (3.24b + Debt 118.1m - CCE 250.7m)
Interest Coverage Ratio = -19.93 (Ebit TTM -215.1m / Interest Expense TTM 10.8m)
FCF Yield = -4.64% (FCF TTM -144.0m / Enterprise Value 3.10b)
FCF Margin = -903.0% (FCF TTM -144.0m / Revenue TTM 16.0m)
Net Margin = -1444 % (Net Income TTM -230.4m / Revenue TTM 16.0m)
Gross Margin = 92.72% ((Revenue TTM 16.0m - Cost of Revenue TTM 1.16m) / Revenue TTM)
Gross Margin QoQ = none% (prev 98.55%)
Tobins Q-Ratio = 6.31 (Enterprise Value 3.10b / Total Assets 492.1m)
Interest Expense / Debt = 2.44% (Interest Expense 2.88m / Debt 118.1m)
Taxrate = -1.57% (negative due to tax credits) (778.0k / -49.6m)
NOPAT = -218.5m (EBIT -215.1m * (1 - -1.57%)) [loss with tax shield] [negative tax rate / tax credits]
Current Ratio = 10.12 (Total Current Assets 300.4m / Total Current Liabilities 29.7m)
Debt / Equity = 0.34 (Debt 118.1m / totalStockholderEquity, last quarter 344.9m)
Debt / EBITDA = -0.34 (negative EBITDA) (Net Debt 73.9m / EBITDA -214.2m)
Debt / FCF = -0.51 (negative FCF - burning cash) (Net Debt 73.9m / FCF TTM -144.0m)
Total Stockholder Equity = 408.0m (last 4 quarters mean from totalStockholderEquity)
RoA = -46.81% (Net Income -230.4m / Total Assets 492.1m)
RoE = -56.47% (Net Income TTM -230.4m / Total Stockholder Equity 408.0m)
RoCE = -41.57% (EBIT -215.1m / Capital Employed (Equity 408.0m + L.T.Debt 109.5m))
RoIC = -42.95% (negative operating profit) (NOPAT -218.5m / Invested Capital 508.8m)
WACC = 11.48% (E(3.24b)/V(3.35b) * Re(11.81%) + D(118.1m)/V(3.35b) * Rd(2.44%) * (1-Tc(-0.02)))
Discount Rate = 11.81% (= CAPM, Blume Beta Adj.)
Shares Correlation 3-Years: 100.0 | Cagr: 16.84%
Fair Price DCF = unknown (Cash Flow -144.0m)
EPS Correlation: 31.97 | EPS CAGR: 29.86% | SUE: 2.14 | # QB: 1
Revenue Correlation: 36.29 | Revenue CAGR: 0.0% | SUE: 0.0 | # QB: 0

Additional Sources for CNTA Stock

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