CRBU Stock Analysis: Caribou Biosciences | NASDAQ

Biotechnology | NASDAQ, USA | Market Cap: 181m USD | 12M Return: 30.9% | Charts, Fundamentals & Technical Analysis

Genome Editing, CAR-T Therapy, Oncology Treatments, Cell Therapy
Total Rating 28
Safety 37
Buy Signal -0.74
Biotechnology
Industry Rotation: +22.4
Market Cap: 181M
Avg Turnover: 3.55M
Risk 3d forecast
Volatility81.4%
VaR 5th Pctl12.9%
VaR vs Median-3.69%
Reward TTM
Sharpe Ratio0.70
Rel. Str. IBD27.8
Rel. Str. Peer Group12.5
Character TTM
Beta2.341
Beta Downside2.884
Hurst Exponent0.446
Drawdowns 3y
Max DD91.12%
CAGR/Max DD-0.41
CAGR/Mean DD-0.57
EPS (Earnings per Share) EPS (Earnings per Share) of CRBU over the last years for every Quarter: "2021-06": -1.55, "2021-09": -0.46, "2021-12": -0.31, "2022-03": -0.32, "2022-06": -0.44, "2022-09": -0.44, "2022-12": -0.44, "2023-03": -0.46, "2023-06": -0.48, "2023-09": -0.12, "2023-12": -0.39, "2024-03": -0.46, "2024-06": -0.42, "2024-09": -0.38, "2024-12": -0.39, "2025-03": -0.43, "2025-06": -0.58, "2025-09": -0.3, "2025-12": -0.28, "2026-03": -0.26,
Last SUE: 0.81
Qual. Beats: 0
Revenue Revenue of CRBU over the last years for every Quarter: 2021-06: 1.476, 2021-09: 3.977, 2021-12: 2.559, 2022-03: 2.664, 2022-06: 4.192, 2022-09: 3.303, 2022-12: 3.692, 2023-03: 3.502, 2023-06: 3.755, 2023-09: 23.662, 2023-12: 3.558, 2024-03: 2.429, 2024-06: 3.464, 2024-09: 2.024, 2024-12: 2.077, 2025-03: 2.353, 2025-06: 2.667, 2025-09: 2.198, 2025-12: 3.941, 2026-03: 2.397,
Rev. CAGR: -36.31%
Rev. Trend: -70.2%
Last SUE: 0.37
Qual. Beats: 0

Warnings

Interest Coverage Ratio Critical
Altman Z'' In Financial Distress Zone
Choppy
Below Avwap Earnings
Below Sma 200d

Tailwinds

Seasonal Tailwind

Seasonality 4.9 years of data

Jan +7.8% 0
Feb +12.7% 0
Mar -8.1% 45
Apr -8.5% 23
May +16.0% 24
Jun -16.3% 0
Jul +73.2% 62
Aug +3.2% 0
Sep +6.9% 0
Oct +2.5% 20
Nov +9.9% 21
Dec -16.4% 26

How good or bad each month usually is (without trend). The score below shows how much you can trust it: 0 = pure chance, >40 gets interesting and >55 is strong.

Description: CRBU Caribou Biosciences

Caribou Biosciences, Inc. (NASDAQ: CRBU) is a clinical-stage biopharmaceutical company headquartered in Berkeley, California, focused on developing allogeneic cell therapies using its proprietary CRISPR hybrid RNA-DNA genome-editing platform. Founded in 2011, the company went public in July 2021 and currently operates as a micro-cap within the Health Care / Biotechnology sector.

The companys clinical pipeline is led by two Phase 1 allogeneic CAR-T cell therapy candidates: Vispacabtagene Regedleucel, an anti-CD19 therapy targeting relapsed or refractory B cell non-Hodgkin lymphoma, and CB-011, an anti-BCMA therapy for relapsed or refractory multiple myeloma. Both programs are being evaluated in early-stage clinical trials.

Caribous business model centers on allogeneic (off-the-shelf) cell therapies, which are manufactured from healthy donor cells rather than a patients own cells, in contrast to autologous approaches. The company leverages CRISPR-based gene editing to engineer these cell therapies with the aim of producing scalable, standardized treatments for hematologic cancers and other diseases.

Headlines to Watch Out For
  • CB-011 Phase 1 multiple myeloma data readout approaches
  • Vispacabtagene Regedleucel Phase 1 lymphoma update due
  • Cash burn raises dilution risk on micro-cap balance sheet
Piotroski VR-10 (Strict) 1.0
Net Income: -133.2m TTM > 0 and > 6% of Revenue
FCF/TA: -0.68 > 0.02 and ΔFCF/TA -16.21 > 1.0
NWC/Revenue: 916.8% < 20% (prev 1.90k%; Δ -987.1% < -1%)
CFO/TA -0.68 > 3% & CFO -101.3m > Net Income -133.2m
Net Debt/EBITDA: error (EBITDA <= 0)
Current Ratio: 6.22 > 1.5 & < 3
Outstanding Shares: last quarter (95.9m) vs 12m ago 3.43% < -2%
Gross Margin: 70.90% > 18% (prev -528.0%; Δ 598.9% > 0.5%)
Asset Turnover: 5.30% > 50% (prev 3.62%; Δ 1.68% > 0%)
Interest Coverage Ratio: -6.16 > 6 (EBIT TTM -115.1m / Interest Expense TTM 18.7m)
Altman Z'' -10.46
A: 0.69 (Total Current Assets 122.4m - Total Current Liabilities 19.7m) / Total Assets 149.0m
B: -4.17 (Retained Earnings -621.6m / Total Assets 149.0m)
C: -0.54 (EBIT TTM -115.1m / Avg Total Assets 211.3m)
D: 2.17 (Book Value of Equity 102.0m / Total Liabilities 47.0m)
Altman-Z'' = -10.46 = D
Beneish M -3.56
DSRI: 0.76 (Receivables 2.36m/2.74m, Revenue 11.2m/9.92m)
GMI: 1.00 (fallback, negative margins)
AQI: 0.32 (AQ_t 0.02 / AQ_t-1 0.07)
SGI: 1.13 (Revenue 11.2m / 9.92m)
TATA: -0.21 (NI -133.2m - CFO -101.3m) / TA 149.0m)
Beneish M = -3.56 (Cap -4..+1) = AAA
What is the price of CRBU shares?

As of July 06, 2026, the stock is trading at USD 1.82 with a total of 1,868,938 shares traded. Over the past week, the price has changed by +15.92%, over one month by -5.21%, over three months by -6.67% and over the past year by +30.94%.

Current recommended Stop Loss: 1.60 (which is 12.1% or 1.7 ATR below the current price).

Is CRBU a buy, sell or hold?

Caribou Biosciences has received a consensus analysts rating of 4.33. Therefore, it is recommended to buy CRBU.

  • StrongBuy: 5
  • Buy: 2
  • Hold: 2
  • Sell: 0
  • StrongSell: 0

What are the forecasts/targets for the CRBU price?
Analysts Target Price 12 559.3%
Caribou Biosciences (CRBU) - Fundamental Data Overview as of 05 July 2026
Market Cap USD = 180.5m (180.5m USD * 1.0 USD.USD)
P/S = 16.1125
P/B = 1.711
Revenue TTM = 11.2m USD
EBIT TTM = -115.1m USD
EBITDA TTM = -112.0m USD
Long Term Debt = 25.7m USD (estimated: total debt 26.9m - short term 1.29m)
Short Term Debt = 1.29m USD (from shortTermDebt, last quarter)
Debt = 26.9m USD (from shortLongTermDebtTotal, last quarter) (leases 26.9m already included)
Net Debt = -90.7m USD (calculated: Debt 26.9m - CCE 117.6m)
Enterprise Value = 89.8m USD (180.5m + Debt 26.9m - CCE 117.6m)
Interest Coverage Ratio = -6.16 (Ebit TTM -115.1m / Interest Expense TTM 18.7m)
EV/FCF = -0.88x (Enterprise Value 89.8m / FCF TTM -101.6m)
 FCF Yield = -113.1% (FCF TTM -101.6m / Enterprise Value 89.8m)
 FCF Margin = -907.3% (FCF TTM -101.6m / Revenue TTM 11.2m)
 Net Margin = -1.19k% (Net Income TTM -133.2m / Revenue TTM 11.2m)
 Gross Margin = 70.90% ((Revenue TTM 11.2m - Cost of Revenue TTM 3.26m) / Revenue TTM)
Gross Margin QoQ = 72.92% (prev 82.69%)
Tobins Q-Ratio = 0.60 (Enterprise Value 89.8m / Total Assets 149.0m)
 Interest Expense / Debt = 69.29% (Interest Expense 18.7m / Debt 26.9m)
 Taxrate = 21.0% (US federal default 21%)
NOPAT = -90.9m (EBIT -115.1m * (1 - 21.00%)) [loss with tax shield]
Current Ratio = 6.22 (Total Current Assets 122.4m / Total Current Liabilities 19.7m)
Debt / Equity = 0.26 (Debt 26.9m / totalStockholderEquity, last quarter 102.0m)
 Debt / EBITDA = 0.81 (negative EBITDA) (Net Debt -90.7m / EBITDA -112.0m)
 Debt / FCF = 0.89 (negative FCF - burning cash) (Net Debt -90.7m / FCF TTM -101.6m)
 Total Stockholder Equity = 133.0m (last 4 quarters mean from totalStockholderEquity)
RoA = -63.04% (Net Income -133.2m / Total Assets 149.0m)
RoE = -100.1% (Net Income TTM -133.2m / Total Stockholder Equity 133.0m)
RoCE = -72.53% (EBIT -115.1m / Capital Employed (Equity 133.0m + L.T.Debt 25.7m))
 RoIC = -69.92% (negative operating profit) (NOPAT -90.9m / Invested Capital 130.1m)
 WACC = 12.37% (E(180.5m)/V(207.5m) * Re(14.22%) + (debt cost/tax rate unavailable))
Discount Rate = 14.22% (= CAPM, Blume Beta Adj.) -> capped to 13.17%
Shares (quarterly) Correlation: 89.44 | Cagr: 12.26%
 [DCF] Fair Price = unknown (Cash Flow -101.6m)
 EPS Correlation: N/A | EPS CAGR: N/A | SUE: 0.81 | # QB: 0
Revenue Correlation: -70.18 | Revenue CAGR: -36.31% | SUE: 0.37 | # QB: 0
EPS current Quarter (2026-06-30): EPS=-0.31 | Chg30d=+2.63% | Revisions=+0% | Analysts=3
EPS next Quarter (2026-09-30): EPS=-0.32 | Chg30d=+0.00% | Revisions=+0% | Analysts=3
EPS current Year (2026-12-31): EPS=-1.25 | Chg30d=+0.66% | Revisions=-25% | GrowthEPS=+15.1% | GrowthRev=+130.0%
EPS next Year (2027-12-31): EPS=-1.40 | Chg30d=+6.67% | Revisions=-25% | GrowthEPS=-12.3% | GrowthRev=+17.2%
[Analyst] Revisions Ratio: -40% (up=0, down=2)