CRSP Stock Analysis: Crispr Therapeutics | NASDAQ

Biotechnology | NASDAQ, USA | Market Cap: 5.360m USD | 12M Return: -28.7% | CH0334081137 | Charts, Fundamentals & Technical Analysis

Gene Editing, Cell Therapy, Cardiovascular Treatments, Diabetes Treatments
Total Rating 19
Safety 50
Buy Signal -0.92
Biotechnology
Industry Rotation: -19.5
Market Cap: 5.36B
Avg Turnover: 92.6M
Risk 3d forecast
Volatility61.2%
VaR 5th Pctl9.65%
VaR vs Median-4.30%
Reward TTM
Sharpe Ratio-0.36
Rel. Str. IBD23.5
Rel. Str. Peer Group34.3
Character TTM
Beta1.693
Beta Downside1.479
Hurst Exponent0.565
Drawdowns 3y
Max DD64.91%
CAGR/Max DD0.10
CAGR/Mean DD0.17
EPS (Earnings per Share) EPS (Earnings per Share) of CRSP over the last years for every Quarter: "2021-09": -1.67, "2021-12": -1.84, "2022-03": -2.32, "2022-06": -2.4, "2022-09": -2.24, "2022-12": -1.41, "2023-03": -0.67, "2023-06": -0.98, "2023-09": -1.41, "2023-12": 1.1, "2024-03": -1.43, "2024-06": -1.49, "2024-09": -1.01, "2024-12": -0.44, "2025-03": -1.58, "2025-06": -1.29, "2025-09": -1.17, "2025-12": -1.37, "2026-03": -1.28, "2026-06": -0.94,
Last SUE: 0.48
Qual. Beats: 0
Revenue Revenue of CRSP over the last years for every Quarter: 2021-09: 0.329, 2021-12: 12.899, 2022-03: 0.178, 2022-06: 0.158, 2022-09: 0.094, 2022-12: 0.006, 2023-03: 100, 2023-06: 70, 2023-09: 0, 2023-12: 200, 2024-03: 0.504, 2024-06: 0.517, 2024-09: 0.602, 2024-12: 35, 2025-03: 0.865, 2025-06: 0.892, 2025-09: 0.889, 2025-12: 0.864, 2026-03: 1.458, 2026-06: 10.181,
Rev. CAGR: -79.21%
Rev. Trend: -89.3%
Last SUE: 0.29
Qual. Beats: 0

Warnings

Volatile
Below Avwap Earnings

Tailwinds

Confidence

Seasonality 9.9 years of data

Jan +5.6% 9
Feb +6.0% 36
Mar -13.3% 56
Apr +5.5% 10
May +9.9% 24
Jun +8.1% 21
Jul +3.7% 12
Aug -5.8% 37
Sep -9.4% 29
Oct -6.5% 27
Nov +6.8% 31
Dec -4.0% 22

How good or bad each month usually is (without trend). The score below shows how much you can trust it: 0 = pure chance, >40 gets interesting and >55 is strong.

Description: CRSP Crispr Therapeutics

CRISPR Therapeutics AG (NASDAQ: CRSP) is a Swiss-based biotechnology company developing gene-editing medicines using its proprietary CRISPR/Cas9 platform, which enables precise modification of genomic DNA sequences. The company was founded in 2013 and listed on the U.S. market in October 2016, and its mid-cap market value reflects its position as a clinical-stage player in the gene-editing space. It has a broad pipeline spanning hemoglobinopathies, CAR T cell therapies, in vivo gene editing, and type 1 diabetes, with its lead product, CASGEVY, being an ex vivo gene-edited cell therapy approved for transfusion-dependent beta-thalassemia and severe sickle cell disease. Strategic collaboration with Vertex Pharmaceuticals supports CASGEVYs commercialization and broader development efforts, illustrating the partnership-driven model common in biotech where large pharma helps fund and distribute advanced therapies.

Headlines to Watch Out For
  • CASGEVY launch uptake drives sickle cell and beta-thalassemia revenue ramp
  • Vertex partnership milestone payments expand operating runway
  • In vivo gene editing pipeline readouts validate platform expansion potential
Piotroski VR-10 (Strict) 0.0
Net Income: -451.1m TTM > 0 and > 6% of Revenue
FCF/TA: -0.14 > 0.02 and ΔFCF/TA 4.25 > 1.0
NWC/Revenue: 16.7k% < 20% (prev 4.36k%; Δ 12.4k% < -1%)
CFO/TA -0.14 > 3% & CFO -369.6m > Net Income -451.1m
Net Debt/EBITDA: error (EBITDA <= 0)
Current Ratio: 17.85 > 1.5 & < 3
Outstanding Shares: last quarter (96.5m) vs 12m ago 10.85% < -2%
Gross Margin: error (current vs previous; cannot be calculated due to missing/invalid data or negative margin)
Asset Turnover: 0.57% > 50% (prev 1.84%; Δ -1.27% > 0%)
Interest Coverage Ratio: error (cannot be calculated; needs correct EBIT TTM and Interest Expense TTM)
Altman Z'' 3.55
A: 0.84 (Total Current Assets 2.37b - Total Current Liabilities 132.9m) / Total Assets 2.65b
B: -0.82 (Retained Earnings -2.16b / Total Assets 2.65b)
C: -0.20 (EBIT TTM -472.7m / Avg Total Assets 2.34b)
D: 1.93 (Book Value of Equity 1.75b / Total Liabilities 904.2m)
Altman-Z'' = 3.55 = A
What is the price of CRSP shares?

As of October 11, 2026, the stock is trading at USD 53.39 with a total of 1,465,256 shares traded. Over the past week, the price has changed by -3.68%, over one month by -0.11%, over three months by -5.24% and over the past year by -28.74%.

Current recommended Stop Loss: 47.30 (which is 11.4% or 2 ATR below the current price).

Is CRSP a buy, sell or hold?

Crispr Therapeutics has received a consensus analysts rating of 3.95. Therefore, it is recommended to buy CRSP.

  • StrongBuy: 8
  • Buy: 5
  • Hold: 9
  • Sell: 0
  • StrongSell: 0

What are the forecasts/targets for the CRSP price?
Analysts Target Price 87.6 64%
Crispr Therapeutics (CRSP) - Fundamental Data Overview as of 05 October 2026
Market Cap USD = 5.36b (5.36b USD * 1.0 USD.USD)
P/E Forward = 23.3645
P/S = 400.2146
P/B = 3.087
P/EG = -0.2142
Revenue TTM = 13.4m USD
EBIT TTM = -472.7m USD
EBITDA TTM = -454.0m USD
Long Term Debt = 586.2m USD (from longTermDebt, last quarter)
Short Term Debt = 18.6m USD (from shortTermDebt, last quarter)
Debt = 981.3m USD (from shortLongTermDebtTotal, last quarter) + Leases 197.6m
Net Debt = -1.38b USD (calculated: Debt 981.3m - CCE 2.36b)
Enterprise Value = 3.98b USD (5.36b + Debt 981.3m - CCE 2.36b)
 Interest Coverage Ratio = unknown (Ebit TTM -472.7m / Interest Expense TTM 0.0)
 EV/FCF = -10.80x (Enterprise Value 3.98b / FCF TTM -368.3m)
FCF Yield = -9.26% (FCF TTM -368.3m / Enterprise Value 3.98b)
 FCF Margin = -2.75k% (FCF TTM -368.3m / Revenue TTM 13.4m)
 Net Margin = -3.37k% (Net Income TTM -451.1m / Revenue TTM 13.4m)
 Gross Margin = unknown ((Revenue TTM 13.4m - Cost of Revenue TTM 218.9m) / Revenue TTM)
 Tobins Q-Ratio = 1.50 (Enterprise Value 3.98b / Total Assets 2.65b)
Interest Expense / Debt = 0.0% (Interest Expense 0.0 / Debt 981.3m)
Taxrate = 21.0% (US federal default 21%)
NOPAT = -373.4m (EBIT -472.7m * (1 - 21.00%)) [loss with tax shield]
Current Ratio = 16.45 (Total Current Assets 2.37b / Total Current Liabilities 144.2m)
Debt / Equity = 0.56 (Debt 981.3m / totalStockholderEquity, last quarter 1.75b)
 Debt / EBITDA = 3.05 (negative EBITDA) (Net Debt -1.38b / EBITDA -454.0m)
 Debt / FCF = 3.75 (negative FCF - burning cash) (Net Debt -1.38b / FCF TTM -368.3m)
 Total Stockholder Equity = 1.85b (last 4 quarters mean from totalStockholderEquity)
RoA = -19.28% (Net Income -451.1m / Total Assets 2.65b)
RoE = -24.39% (Net Income TTM -451.1m / Total Stockholder Equity 1.85b)
RoCE = -19.41% (EBIT -472.7m / Capital Employed (Equity 1.85b + L.T.Debt 586.2m))
 RoIC = -14.73% (negative operating profit) (NOPAT -373.4m / Invested Capital 2.54b)
 WACC = 10.09% (E(5.36b)/V(6.34b) * Re(11.94%) + D(981.3m)/V(6.34b) * Rd(0.0%) * (1-Tc(0.21)))
Discount Rate = 11.94% (= CAPM, Blume Beta Adj.)
Shares (quarterly) Correlation: 94.28 | Cagr: 7.63%
 [DCF] Fair Price = unknown (Cash Flow -368.3m)
 EPS Correlation: N/A | EPS CAGR: N/A | SUE: 0.48 | # QB: 0
Revenue Correlation: -89.33 | Revenue CAGR: -79.21% | SUE: 0.29 | # QB: 0
EPS current Quarter (2026-09-30): EPS=-1.05 | Chg30d=+10.60% | Revisions=+50% | Analysts=17
EPS current Year (2026-12-31): EPS=-4.45 | Chg30d=+0.00% | Revisions=+50% | GrowthEPS=+31.3% | GrowthRev=+1063.3%
EPS next Year (2027-12-31): EPS=-3.50 | Chg30d=+0.00% | Revisions=+82% | GrowthEPS=+21.3% | GrowthRev=+283.5%
[Analyst] Revisions Ratio: +70% (up=35, down=5)