(CRSP) Crispr Therapeutics - Ratings and Ratios

Exchange: NASDAQ • Country: Switzerland • Currency: USD • Type: Common Stock • ISIN: CH0334081137

Beta Thalassemia Therapy, Sickle Cell Therapy, CAR T Cells, Diabetes Therapy

CRSP EPS (Earnings per Share)

EPS (Earnings per Share) of CRSP over the last years for every Quarter: "2020-03": -1.1459923711167, "2020-06": -1.2968917645028, "2020-09": -1.3178555390022, "2020-12": -1.5260002708733, "2021-03": -1.508735394346, "2021-06": 9.4372280919826, "2021-09": -1.6667387614123, "2021-12": -1.8427730310751, "2022-03": -2.3245259623105, "2022-06": -2.3974466317393, "2022-09": -2.2371910306774, "2022-12": -1.4115386824788, "2023-03": -0.67446648957129, "2023-06": -0.9829171676712, "2023-09": -1.4122429140417, "2023-12": 1.0986439560872, "2024-03": -1.4254119465099, "2024-06": -1.4885381572734, "2024-09": -1.0082947146125, "2024-12": -0.43656825130493, "2025-03": -1.5824768119602, "2025-06": -2.3951960326038,

CRSP Revenue

Revenue of CRSP over the last years for every Quarter: 2020-03: 0.157, 2020-06: 0.044, 2020-09: 0.148, 2020-12: 0.194, 2021-03: 0.202, 2021-06: 900.202, 2021-09: 0.329, 2021-12: 12.348, 2022-03: 0.178, 2022-06: 0.158, 2022-09: 0.094, 2022-12: 0.006, 2023-03: 100, 2023-06: 70, 2023-09: 0, 2023-12: 200, 2024-03: 0.504, 2024-06: 0.517, 2024-09: 0.602, 2024-12: 35, 2025-03: 0.865, 2025-06: 0.892,

Description: CRSP Crispr Therapeutics

CRISPR Therapeutics AG is a gene editing company leveraging its CRISPR/Cas9 platform to develop innovative gene-based medicines for serious human diseases. The companys pipeline includes various therapeutic programs targeting hemoglobinopathies, CAR T cell therapies, and type 1 diabetes, with a focus on treating diseases with high unmet medical needs.

Key highlights of the companys pipeline include CASGEVY, an ex vivo CRISPR/Cas9 gene-edited cell therapy for treating transfusion-dependent beta-thalassemia and severe sickle cell disease, as well as investigational CAR T programs targeting glypican-3 (GPC3) for solid tumors. The company is also developing CAR T cell therapies, including CTX112 and CTX131, and in vivo gene editing therapies, such as CTX310 and CTX320, to address cardiovascular disease.

From a financial perspective, CRISPR Therapeutics AG has a market capitalization of approximately $4.9 billion USD, with a forward P/E ratio of 23.36. The companys return on equity (ROE) is currently negative, at -20.08%, indicating significant investment in research and development. To evaluate the companys performance, key performance indicators (KPIs) to monitor include: R&D expenses as a percentage of revenue, pipeline progress (e.g., number of programs in clinical trials, approval milestones), and cash burn rate.

Strategic partnerships with companies like Vertex Pharmaceuticals Incorporated, Nkarta, Inc., and Capsida Biotherapeutics are crucial to CRISPR Therapeutics AGs success, as they provide access to new technologies, expertise, and potential revenue streams. The companys ability to execute on its pipeline and forge new partnerships will be critical to driving growth and delivering returns to shareholders.

CRSP Stock Overview

Market Cap in USD 4,714m
Sub-Industry Biotechnology
IPO / Inception 2016-10-19

CRSP Stock Ratings

Growth Rating -21.0%
Fundamental 27.2%
Dividend Rating -
Return 12m vs S&P 500 -0.35%
Analyst Rating 3.96 of 5

CRSP Dividends

Currently no dividends paid

CRSP Growth Ratios

Growth Correlation 3m 28.8%
Growth Correlation 12m 15%
Growth Correlation 5y -77.2%
CAGR 5y -7.32%
CAGR/Max DD 3y -0.11
CAGR/Mean DD 3y -0.21
Sharpe Ratio 12m -0.91
Alpha 7.23
Beta 0.701
Volatility 51.98%
Current Volume 2000.7k
Average Volume 20d 1726.5k
Stop Loss 53.4 (-5.1%)
Signal 0.59

Piotroski VR‑10 (Strict, 0-10) 0.0

Net Income (-467.8m TTM) > 0 and > 6% of Revenue (6% = 2.24m TTM)
FCFTA -0.07 (>2.0%) and ΔFCFTA 4.51pp (YES ≥ +1.0pp, WARN ≥ +0.5pp)
NWC/Revenue 4361 % (prev 936.5%; Δ 3425 pp) (YES ≤20% & Δ≤-1pp; WARN ≤25% & Δ≤0 oder ≤40% & Δ≤-3pp)
CFO/TA -0.16 (>3.0%) and CFO -324.8m > Net Income -467.8m (YES >=105%, WARN >=100%)
NO Net Debt/EBITDA fails (EBITDA <= 0)
Current Ratio 16.61 (target 1.5–3.0; WARN 1.2–<1.5 or >3.0–5.0; CFO/TA gate active)
Outstanding Shares last Quarter (87.1m) change vs 12m ago 2.53% (target <= -2.0% for YES)
Gross Margin -228.1% (prev 24.29%; Δ -252.4pp) >=18% & Δ>=+0.5pp (WARN >=15% & Δ>=0)
Asset Turnover 1.71% (prev 8.59%; Δ -6.88pp) >=50% & Δ>=+2pp (WARN >=35% & Δ>=0)
error: Interest Coverage Ratio cannot be calculated (needs EBITDA TTM and Interest Expense TTM)

Altman Z'' -4.73

(A) 0.80 = (Total Current Assets 1.73b - Total Current Liabilities 104.4m) / Total Assets 2.03b
(B) -0.84 = Retained Earnings (Balance) -1.71b / Total Assets 2.03b
(C) -0.24 = EBIT TTM -530.5m / Avg Total Assets 2.18b
(D) -5.35 = Book Value of Equity -1.70b / Total Liabilities 318.6m
Total Rating: -4.73 = (6.56 * A) + (3.26 * B) + (6.72 * C) + (1.05 * D)

ValueRay F-Score (Strict, 0-100) 27.15

1. Piotroski 0.0pt = -5.0
2. FCF Yield -4.47% = -2.23
3. FCF Margin data missing
4. Debt/Equity 0.15 = 2.49
5. Debt/Ebitda -0.49 = -2.50
6. ROIC - WACC -37.08% = -12.50
7. RoE -25.25% = -2.50
8. Rev. Trend -9.82% = -0.49
9. Rev. CAGR 0.0% = 0.0
10. EPS Trend -4.50% = -0.11
11. EPS CAGR 0.0% = 0.0

What is the price of CRSP shares?

As of September 15, 2025, the stock is trading at USD 56.26 with a total of 2,000,726 shares traded.
Over the past week, the price has changed by +3.99%, over one month by -4.35%, over three months by +35.31% and over the past year by +17.85%.

Is Crispr Therapeutics a good stock to buy?

No, based on ValueRay´s Fundamental Analyses, Crispr Therapeutics (NASDAQ:CRSP) is currently (September 2025) a stock to sell. It has a ValueRay Fundamental Rating of 27.15 and therefor a negative outlook according to the companies health.
Based on momentum, paid dividends and discounted-cash-flow analyses, the fair value of CRSP is around 48.48 USD . This means that CRSP is currently overvalued and has a potential downside of -13.83%.

Is CRSP a buy, sell or hold?

Crispr Therapeutics has received a consensus analysts rating of 3.96. Therefore, it is recommended to buy CRSP.
  • Strong Buy: 12
  • Buy: 5
  • Hold: 10
  • Sell: 0
  • Strong Sell: 1

What are the forecasts/targets for the CRSP price?

Issuer Target Up/Down from current
Wallstreet Target Price 82 45.8%
Analysts Target Price 82 45.8%
ValueRay Target Price 54 -4%

Last update: 2025-09-01 04:39

CRSP Fundamental Data Overview

Market Cap USD = 4.71b (4.71b USD * 1.0 USD.USD)
CCE Cash And Equivalents = 1.72b USD (Cash And Short Term Investments, last quarter)
P/E Forward = 23.3645
P/S = 123.8886
P/B = 2.7549
P/EG = -0.2142
Beta = 1.803
Revenue TTM = 37.4m USD
EBIT TTM = -530.5m USD
EBITDA TTM = -511.5m USD
Long Term Debt = 214.2m USD (from nonCurrentLiabilitiesTotal, last quarter)
Short Term Debt = 36.1m USD (from shortTermDebt, last quarter)
Debt = 250.3m USD (Calculated: Short Term 36.1m + Long Term 214.2m)
Net Debt = 18.3m USD (from netDebt column, last quarter)
Enterprise Value = 3.24b USD (4.71b + Debt 250.3m - CCE 1.72b)
Interest Coverage Ratio = unknown (Ebit TTM -530.5m / Interest Expense TTM 0.0)
FCF Yield = -4.47% (FCF TTM -144.7m / Enterprise Value 3.24b)
FCF Margin = -387.3% (FCF TTM -144.7m / Revenue TTM 37.4m)
Net Margin = -1252 % (Net Income TTM -467.8m / Revenue TTM 37.4m)
Gross Margin = -228.1% ((Revenue TTM 37.4m - Cost of Revenue TTM 122.6m) / Revenue TTM)
Tobins Q-Ratio = -1.90 (set to none) (Enterprise Value 3.24b / Book Value Of Equity -1.70b)
Interest Expense / Debt = 7.11% (Interest Expense 17.8m / Debt 250.3m)
Taxrate = 21.0% (US default)
NOPAT = -530.5m (EBIT -530.5m, no tax applied on loss)
Current Ratio = 16.61 (Total Current Assets 1.73b / Total Current Liabilities 104.4m)
Debt / Equity = 0.15 (Debt 250.3m / last Quarter total Stockholder Equity 1.71b)
Debt / EBITDA = -0.49 (Net Debt 18.3m / EBITDA -511.5m)
Debt / FCF = -1.73 (Debt 250.3m / FCF TTM -144.7m)
Total Stockholder Equity = 1.85b (last 4 quarters mean)
RoA = -23.05% (Net Income -467.8m, Total Assets 2.03b )
RoE = -25.25% (Net Income TTM -467.8m / Total Stockholder Equity 1.85b)
RoCE = -25.66% (Ebit -530.5m / (Equity 1.85b + L.T.Debt 214.2m))
RoIC = -28.63% (NOPAT -530.5m / Invested Capital 1.85b)
WACC = 8.45% (E(4.71b)/V(4.96b) * Re(8.60%)) + (D(250.3m)/V(4.96b) * Rd(7.11%) * (1-Tc(0.21)))
Shares Correlation 3-Years: 100.00 | Cagr: 1.00%
Discount Rate = 8.60% (= CAPM, Blume Beta Adj.)
Fair Price DCF = unknown (Cash Flow -144.7m)
Revenue Correlation: -9.82 | Revenue CAGR: 0.0%
Rev Growth-of-Growth: 76.48
EPS Correlation: -4.50 | EPS CAGR: 0.0%
EPS Growth-of-Growth: -95.55

Additional Sources for CRSP Stock

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Fund Manager Positions: Dataroma | Stockcircle