(CTNM) Contineum Therapeutics - Overview

Sector: Healthcare | Industry: Biotechnology | Exchange: NASDAQ (USA) | Market Cap: 513m USD | Total Return: 254.5% in 12m

Small Molecules, LPA1R Inhibitors, M1R Inhibitors
Total Rating 42
Safety 57
Buy Signal -0.32
Biotechnology
Industry Rotation: -8.2
Market Cap: 513M
Avg Turnover: 2.06M
Risk 3d forecast
Volatility83.2%
VaR 5th Pctl13.6%
VaR vs Median-0.72%
Reward TTM
Sharpe Ratio1.84
Rel. Str. IBD90.5
Rel. Str. Peer Group79.9
Character TTM
Beta1.281
Beta Downside1.460
Hurst Exponent0.483
Drawdowns 3y
Max DD84.37%
CAGR/Max DD-0.06
CAGR/Mean DD-0.12

Warnings

Share dilution 44.3% YoY

High Debt while negative Cash Flow

Altman Z'' -15.00 < 1.0 - financial distress zone

Volatile

Tailwinds

Leader

Description: CTNM Contineum Therapeutics

Contineum Therapeutics, Inc. (CTNM) is a clinical-stage biopharmaceutical firm focused on developing small molecule therapies for neuroscience, inflammation, and immunology. Its primary pipeline includes PIPE-791, a brain-penetrant LPA1R inhibitor targeting idiopathic pulmonary fibrosis and chronic pain, and PIPE-307, aimed at depression and multiple sclerosis. Formerly known as Pipeline Therapeutics, the company operates out of San Diego, California.

The clinical-stage biotech sector typically operates on a high-risk, high-reward model where valuation is driven by trial data milestones rather than immediate revenue. Small molecule development is often prioritized in neuroscience due to the ability of these compounds to cross the blood-brain barrier more effectively than larger biologics. Investors can further evaluate these technical pipeline milestones by utilizing the data tools at ValueRay.

Headlines to Watch Out For
  • PIPE-791 clinical trial milestones drive valuation in pulmonary fibrosis and chronic pain
  • Partnership revenue from Johnson & Johnson collaboration fuels PIPE-307 development for MS
  • Regulatory approval pathways for brain-penetrant small molecules impact long-term commercial viability
  • High research and development expenditures necessitate future capital raises or dilutive financing
Piotroski VR-10 (Strict) 0.0
Net Income: error (cannot be calculated; needs Net Income TTM and Revenue TTM)
FCF/TA: -0.22 > 0.02 and ΔFCF/TA -2.11 > 1.0
NWC/Revenue: error (cannot be calculated; needs Current Assets/Liabilities and Revenue current+prev)
CFO/TA -0.22 > 3% & CFO -57.2m > Net Income -58.4m
Net Debt/EBITDA: error (EBITDA <= 0)
Current Ratio: 38.00 > 1.5 & < 3
Outstanding Shares: last quarter (37.3m) vs 12m ago 44.34% < -2%
Gross Margin: error (current vs previous; cannot be calculated due to missing/invalid data or negative margin)
Asset Turnover: 0.0% > 50% (prev 0.12%; Δ -0.12% > 0%)
Interest Coverage Ratio: error (cannot be calculated; needs correct EBITDA TTM and Interest Expense TTM)
Altman Z'' -15.00
A: 0.94 (Total Current Assets 253.0m - Total Current Liabilities 6.66m) / Total Assets 261.3m
B: -0.73 (Retained Earnings -191.8m / Total Assets 261.3m)
C: -0.28 (EBIT TTM -65.1m / Avg Total Assets 229.8m)
D: -16.98 (Book Value of Equity -192.1m / Total Liabilities 11.3m)
Altman-Z'' = -15.95 = D
What is the price of CTNM shares?

As of May 24, 2026, the stock is trading at USD 14.37 with a total of 155,132 shares traded.
Over the past week, the price has changed by +1.02%, over one month by +6.94%, over three months by -11.38% and over the past year by +254.48%.

Is CTNM a buy, sell or hold?

Contineum Therapeutics has received a consensus analysts rating of 4.60. Therefore, it is recommended to buy CTNM.

  • StrongBuy: 3
  • Buy: 2
  • Hold: 0
  • Sell: 0
  • StrongSell: 0

What are the forecasts/targets for the CTNM price?
Analysts Target Price 22.3 55.4%
Contineum Therapeutics (CTNM) - Fundamental Data Overview as of 24 May 2026
P/S = 11.147
P/B = 2.174
Revenue TTM = 0.0 USD
EBIT TTM = -65.1m USD
EBITDA TTM = -64.7m USD
Long Term Debt = 4.65m USD (estimated: total debt 6.95m - short term 2.30m)
Short Term Debt = 2.30m USD (from shortTermDebt, last quarter)
Debt = 15.2m USD (from shortLongTermDebtTotal, last quarter) + Leases 8.25m
Net Debt = -231.1m USD (calculated: Debt 15.2m - CCE 246.3m)
Enterprise Value = 281.8m USD (512.9m + Debt 15.2m - CCE 246.3m)
 Interest Coverage Ratio = unknown (Ebit TTM -65.1m / Interest Expense TTM 0.0)
 EV/FCF = -4.89x (Enterprise Value 281.8m / FCF TTM -57.7m)
FCF Yield = -20.46% (FCF TTM -57.7m / Enterprise Value 281.8m)
 FCF Margin = unknown (Revenue TTM is 0 or missing)
 Net Margin = unknown
 Gross Margin = unknown ((Revenue TTM 0.0 - Cost of Revenue TTM 328k) / Revenue TTM)
 Tobins Q-Ratio = 1.08 (Enterprise Value 281.8m / Total Assets 261.3m)
Interest Expense / Debt = 0.0% (Interest Expense 0.0 / Debt 15.2m)
Taxrate = 21.0% (US default 21%)
NOPAT = -51.4m (EBIT -65.1m * (1 - 21.00%)) [loss with tax shield]
Current Ratio = 38.00 (Total Current Assets 253.0m / Total Current Liabilities 6.66m)
Debt / Equity = 0.06 (Debt 15.2m / totalStockholderEquity, last quarter 250.0m)
 Debt / EBITDA = 3.57 (negative EBITDA) (Net Debt -231.1m / EBITDA -64.7m)
 Debt / FCF = 4.01 (negative FCF - burning cash) (Net Debt -231.1m / FCF TTM -57.7m)
 Total Stockholder Equity = 215.7m (last 4 quarters mean from totalStockholderEquity)
RoA = -25.43% (Net Income -58.4m / Total Assets 261.3m)
RoE = -14.34% (Net Income TTM -58.4m / Total Stockholder Equity 407.6m)
RoCE = -15.79% (EBIT -65.1m / Capital Employed (Equity 407.6m + L.T.Debt 4.65m))
 RoIC = -20.14% (negative operating profit) (NOPAT -51.4m / Invested Capital 255.2m)
 WACC = 10.19% (E(512.9m)/V(528.1m) * Re(10.49%) + D(15.2m)/V(528.1m) * Rd(0.0%) * (1-Tc(0.21)))
Discount Rate = 10.49% (= CAPM, Blume Beta Adj.)
Shares (quarterly) Correlation: 98.88 | Cagr: 19.24%
 [DCF] Fair Price = unknown (Cash Flow -57.7m)
 EPS Correlation: N/A | EPS CAGR: N/A | SUE: 0.42 | # QB: 0
Revenue Correlation: N/A | Revenue CAGR: N/A | SUE: N/A | # QB: 0
EPS current Quarter (2026-06-30): EPS=-0.45 | Chg30d=+19.48% | Revisions=-14% | Analysts=7
EPS next Quarter (2026-09-30): EPS=-0.43 | Chg30d=+17.58% | Revisions=-14% | Analysts=7
EPS current Year (2026-12-31): EPS=-1.65 | Chg30d=+19.88% | Revisions=-27% | GrowthEPS=+24.1% | GrowthRev=+0.0%
EPS next Year (2027-12-31): EPS=-1.81 | Chg30d=+16.58% | Revisions=-20% | GrowthEPS=-10.2% | GrowthRev=+0.0%
[Analyst] Revisions Ratio: -27%