(CYTK) Cytokinetics - Overview

Exchange: NASDAQ • Country: United States • Currency: USD • Type: Common Stock • ISIN: US23282W6057

Stock: Cardiac Activator, Cardiac Inhibitor, Skeletal Activator

Total Rating 42
Risk 30
Buy Signal 0.17

EPS (Earnings per Share)

EPS (Earnings per Share) of CYTK over the last years for every Quarter: "2020-12": -0.62, "2021-03": -0.66, "2021-06": -0.86, "2021-09": -0.95, "2021-12": -0.36, "2022-03": -1.02, "2022-06": -0.23, "2022-09": -1.52, "2022-12": -1.45, "2023-03": -1.38, "2023-06": -1.34, "2023-09": -1.35, "2023-12": -1.38, "2024-03": -1.33, "2024-06": -1.31, "2024-09": -1.36, "2024-12": -1.26, "2025-03": -1.36, "2025-06": -1.12, "2025-09": -2.55, "2025-12": 0,

Revenue

Revenue of CYTK over the last years for every Quarter: 2020-12: 6.722, 2021-03: 6.548, 2021-06: 2.843, 2021-09: 5.437, 2021-12: 55.6, 2022-03: 1.148, 2022-06: 88.968, 2022-09: 2.515, 2022-12: 1.957, 2023-03: 4.613, 2023-06: 0.867, 2023-09: 0.378, 2023-12: 1.672, 2024-03: 0.835, 2024-06: 0.249, 2024-09: 0.463, 2024-12: 16.927, 2025-03: 1.579, 2025-06: 66.769, 2025-09: 1.936, 2025-12: null,
Risk 5d forecast
Volatility 54.4%
Relative Tail Risk -14.8%
Reward TTM
Sharpe Ratio 0.84
Alpha 25.96
Character TTM
Beta 0.613
Beta Downside 0.426
Drawdowns 3y
Max DD 72.39%
CAGR/Max DD 0.18

Description: CYTK Cytokinetics January 08, 2026

Cytokinetics Inc. (NASDAQ:CYTK) is a late-stage biopharma focused on small-molecule modulators of muscle contractility. Its pipeline includes the cardiac myosin activator omecamtiv mecarbil (Phase III heart-failure trial), the fast skeletal muscle troponin activator CK-089 (Phase I), the cardiac myosin inhibitor CK-586 (Phase II), and aficamten, an oral cardiac myosin inhibitor now in Phase III for hypertrophic cardiomyopathy (HCM). The company also holds a strategic alliance with Ji Xing Pharmaceuticals for aficamten’s development and commercialization in Japan.

Key quantitative context (as of FY 2023): cash and short-term investments of roughly $380 million, giving a runway of ~2 years at current burn rates; market capitalization around $1.1 billion, reflecting a price-to-sales multiple of ~30× the modest 2022 revenue of $35 million. The U.S. heart-failure therapeutic market is projected to exceed $5 billion by 2028, while HCM prevalence (≈0.2 % of adults) supports a niche market valued at $1–2 billion, both of which are driving investor interest in muscle-targeted therapeutics. Biotech sector R&D intensity remains high, with average R&D spend ≈25 % of revenue, underscoring the importance of cash efficiency for CYTK’s upcoming trial readouts.

For a deeper, data-driven look at CYTK’s valuation dynamics, you might find ValueRay’s analytical platform worth exploring.

Piotroski VR‑10 (Strict, 0-10) 0.0

Net Income: -751.9m TTM > 0 and > 6% of Revenue
FCF/TA: -0.32 > 0.02 and ΔFCF/TA -3.22 > 1.0
NWC/Revenue: 957.7% < 20% (prev 28.2k%; Δ -27.3k% < -1%)
CFO/TA -0.30 > 3% & CFO -432.9m > Net Income -751.9m
Net Debt/EBITDA: error (EBITDA <= 0)
Current Ratio: 6.88 > 1.5 & < 3
Outstanding Shares: last quarter (120.0m) vs 12m ago 1.95% < -2%
Gross Margin: -127.5% > 18% (prev -101.8%; Δ -2578 % > 0.5%)
Asset Turnover: 6.07% > 50% (prev 0.22%; Δ 5.85% > 0%)
Interest Coverage Ratio: -6.82 > 6 (EBITDA TTM -646.2m / Interest Expense TTM 96.1m)

Altman Z'' -8.52

A: 0.58 (Total Current Assets 977.3m - Total Current Liabilities 142.1m) / Total Assets 1.44b
B: -2.30 (Retained Earnings -3.30b / Total Assets 1.44b)
C: -0.46 (EBIT TTM -655.8m / Avg Total Assets 1.44b)
D: -1.69 (Book Value of Equity -3.30b / Total Liabilities 1.96b)
Altman-Z'' Score: -8.52 = D

Beneish M 1.00

DSRI: 0.27 (Receivables 1.81m/244.0k, Revenue 87.2m/3.22m)
GMI: 1.00 (fallback, negative margins)
AQI: 1.10 (AQ_t 0.21 / AQ_t-1 0.19)
SGI: 27.09 (Revenue 87.2m / 3.22m)
TATA: -0.22 (NI -751.9m - CFO -432.9m) / TA 1.44b)
Beneish M-Score: 14.92 (Cap -4..+1) = D

What is the price of CYTK shares?

As of February 10, 2026, the stock is trading at USD 63.36 with a total of 1,051,037 shares traded.
Over the past week, the price has changed by -2.76%, over one month by +1.36%, over three months by +1.86% and over the past year by +50.11%.

Is CYTK a buy, sell or hold?

Cytokinetics has received a consensus analysts rating of 4.29. Therefore, it is recommended to buy CYTK.
  • StrongBuy: 9
  • Buy: 9
  • Hold: 3
  • Sell: 0
  • StrongSell: 0

What are the forecasts/targets for the CYTK price?

Issuer Target Up/Down from current
Wallstreet Target Price 89.4 41.2%
Analysts Target Price 89.4 41.2%
ValueRay Target Price 71.6 13%

CYTK Fundamental Data Overview February 03, 2026

P/S = 88.5888
P/B = 60.3093
P/EG = -0.42
Revenue TTM = 87.2m USD
EBIT TTM = -655.8m USD
EBITDA TTM = -646.2m USD
Long Term Debt = 1.05b USD (from longTermDebt, last quarter)
Short Term Debt = 37.9m USD (from shortTermDebt, last quarter)
Debt = 1.20b USD (from shortLongTermDebtTotal, last quarter)
Net Debt = 968.3m USD (from netDebt column, last quarter)
Enterprise Value = 7.96b USD (7.73b + Debt 1.20b - CCE 962.5m)
Interest Coverage Ratio = -6.82 (Ebit TTM -655.8m / Interest Expense TTM 96.1m)
EV/FCF = -17.56x (Enterprise Value 7.96b / FCF TTM -453.4m)
FCF Yield = -5.70% (FCF TTM -453.4m / Enterprise Value 7.96b)
FCF Margin = -519.9% (FCF TTM -453.4m / Revenue TTM 87.2m)
Net Margin = -862.2% (Net Income TTM -751.9m / Revenue TTM 87.2m)
Gross Margin = -127.5% ((Revenue TTM 87.2m - Cost of Revenue TTM 198.4m) / Revenue TTM)
Gross Margin QoQ = -38.38% (prev none%)
Tobins Q-Ratio = 5.54 (Enterprise Value 7.96b / Total Assets 1.44b)
Interest Expense / Debt = 2.20% (Interest Expense 26.3m / Debt 1.20b)
Taxrate = 21.0% (US default 21%)
NOPAT = -518.1m (EBIT -655.8m * (1 - 21.00%)) [loss with tax shield]
Current Ratio = 6.88 (Total Current Assets 977.3m / Total Current Liabilities 142.1m)
Debt / Equity = -2.30 (negative equity) (Debt 1.20b / totalStockholderEquity, last quarter -521.1m)
Debt / EBITDA = -1.50 (negative EBITDA) (Net Debt 968.3m / EBITDA -646.2m)
Debt / FCF = -2.14 (negative FCF - burning cash) (Net Debt 968.3m / FCF TTM -453.4m)
Total Stockholder Equity = -322.9m (last 4 quarters mean from totalStockholderEquity)
RoA = -52.35% (Net Income -751.9m / Total Assets 1.44b)
RoE = 232.9% (negative equity) (Net Income TTM -751.9m / Total Stockholder Equity -322.9m)
RoCE = -90.41% (EBIT -655.8m / Capital Employed (Equity -322.9m + L.T.Debt 1.05b))
RoIC = -114.1% (out of range, set to none) (NOPAT -518.1m / Invested Capital 454.2m)
WACC = 7.31% (E(7.73b)/V(8.92b) * Re(8.17%) + D(1.20b)/V(8.92b) * Rd(2.20%) * (1-Tc(0.21)))
Discount Rate = 8.17% (= CAPM, Blume Beta Adj.)
Shares Correlation 3-Years: 100.0 | Cagr: 10.05%
Fair Price DCF = unknown (Cash Flow -453.4m)
EPS Correlation: -2.87 | EPS CAGR: 13.59% | SUE: 4.0 | # QB: 1
Revenue Correlation: -18.06 | Revenue CAGR: -59.15% | SUE: -0.18 | # QB: 0
EPS next Quarter (2026-03-31): EPS=-1.57 | Chg30d=+0.020 | Revisions Net=+1 | Analysts=6
EPS next Year (2026-12-31): EPS=-5.95 | Chg30d=-0.126 | Revisions Net=+0 | Growth EPS=+2.8% | Growth Revenue=+52.6%

Additional Sources for CYTK Stock

News: Wall Street Journal | Benzinga | Yahoo Finance
Fund Manager Positions: Dataroma | Stockcircle