(DSGN) Design Therapeutics - Overview

Exchange: NASDAQ • Country: United States • Currency: USD • Type: Common Stock • ISIN: US25056L1035

Stock: GeneTAC, Friedreich, Ataxia, Myotonic, Dystrophy

Total Rating 45
Risk 36
Buy Signal 0.43

EPS (Earnings per Share)

EPS (Earnings per Share) of DSGN over the last years for every Quarter: "2020-12": null, "2021-03": -0.31, "2021-06": -0.14, "2021-09": -0.21, "2021-12": -0.2, "2022-03": -0.24, "2022-06": -0.27, "2022-09": -0.32, "2022-12": -0.31, "2023-03": -0.35, "2023-06": -0.36, "2023-09": -0.28, "2023-12": -0.21, "2024-03": -0.2, "2024-06": -0.21, "2024-09": -0.23, "2024-12": -0.24, "2025-03": -0.31, "2025-06": -0.34, "2025-09": -0.3, "2025-12": 0,

Revenue

Revenue of DSGN over the last years for every Quarter: 2020-12: 0.033, 2021-03: 0, 2021-06: 0, 2021-09: 0, 2021-12: 0, 2022-03: 0, 2022-06: 0, 2022-09: 0, 2022-12: 0, 2023-03: 0, 2023-06: 0, 2023-09: 0, 2023-12: 0.838, 2024-03: 0, 2024-06: 0, 2024-09: 0, 2024-12: 0.588, 2025-03: 0, 2025-06: 0, 2025-09: 0, 2025-12: null,
Risk 5d forecast
Volatility 87.2%
Relative Tail Risk -11.4%
Reward TTM
Sharpe Ratio 1.36
Alpha 95.96
Character TTM
Beta 0.975
Beta Downside 0.924
Drawdowns 3y
Max DD 75.55%
CAGR/Max DD 0.18

Description: DSGN Design Therapeutics January 01, 2026

Design Therapeutics, Inc. (NASDAQ:DSGN) is a clinical-stage biotech that leverages its GeneTAC platform to create small-molecule drugs targeting nucleotide-repeat expansion disorders. Its pipeline focuses on four monogenic diseases-Friedreich’s Ataxia, Myotonic Dystrophy Type-1, Fuchs Endothelial Corneal Dystrophy, and Huntington’s Disease-each of which involves mitochondrial dysfunction or neuro-muscular degeneration. The company, incorporated in 2017 and based in Carlsbad, California, is positioned as a pure-play genetics-focused therapeutic developer within the U.S. biotechnology sub-industry.

As of the most recent 10-Q, DSGN reported a cash balance of roughly $55 million, giving it an estimated 12-month runway at current burn rates (~$4.5 million per quarter). The market values the firm at approximately $140 million, reflecting a price-to-sales multiple of ~12× for its pre-revenue pipeline-a premium that aligns with investor appetite for rare-disease assets. Sector-wide, the gene-repeat expansion niche has attracted $1.2 billion of venture capital in the past 12 months, and the FDA’s recent guidance on accelerated pathways for neurodegenerative indications could shorten time-to-market for DSGN’s lead candidates.

For a deeper quantitative view, consider reviewing ValueRay’s analyst platform to explore DSGN’s financials and comparable peer metrics.

Piotroski VR‑10 (Strict, 0-10) 0.0

Net Income: -67.4m TTM > 0 and > 6% of Revenue
FCF/TA: -0.25 > 0.02 and ΔFCF/TA -7.01 > 1.0
NWC/Revenue: 33.6k% < 20% (prev 29.8k%; Δ 3839 % < -1%)
CFO/TA -0.25 > 3% & CFO -52.3m > Net Income -67.4m
Net Debt/EBITDA: error (EBITDA <= 0)
Current Ratio: 18.71 > 1.5 & < 3
Outstanding Shares: last quarter (57.0m) vs 12m ago 0.58% < -2%
Gross Margin: error (current vs previous; cannot be calculated due to missing/invalid data or negative margin)
Asset Turnover: 0.25% > 50% (prev 0.32%; Δ -0.07% > 0%)
Interest Coverage Ratio: -12.74 > 6 (EBITDA TTM -72.6m / Interest Expense TTM -5.75m)

Altman Z'' -15.00

A: 0.93 (Total Current Assets 209.0m - Total Current Liabilities 11.2m) / Total Assets 211.8m
B: -1.33 (Retained Earnings -281.0m / Total Assets 211.8m)
C: -0.31 (EBIT TTM -73.2m / Avg Total Assets 236.7m)
D: -23.29 (Book Value of Equity -280.6m / Total Liabilities 12.1m)
Altman-Z'' Score: -24.73 = D

Beneish M -3.36

DSRI: 1.67 (Receivables 1.38m/1.18m, Revenue 588.0k/838.0k)
GMI: 1.00 (fallback, negative margins)
AQI: 0.0 (AQ_t 0.0 / AQ_t-1 0.00)
SGI: 0.70 (Revenue 588.0k / 838.0k)
TATA: -0.07 (NI -67.4m - CFO -52.3m) / TA 211.8m)
Beneish M-Score: -3.36 (Cap -4..+1) = AA

What is the price of DSGN shares?

As of February 09, 2026, the stock is trading at USD 10.27 with a total of 246,779 shares traded.
Over the past week, the price has changed by -1.34%, over one month by +11.87%, over three months by +38.22% and over the past year by +141.08%.

Is DSGN a buy, sell or hold?

Design Therapeutics has received a consensus analysts rating of 3.33. Therefor, it is recommend to hold DSGN.
  • StrongBuy: 0
  • Buy: 1
  • Hold: 2
  • Sell: 0
  • StrongSell: 0

What are the forecasts/targets for the DSGN price?

Issuer Target Up/Down from current
Wallstreet Target Price 14.4 40.2%
Analysts Target Price 14.4 40.2%
ValueRay Target Price 11.5 11.6%

DSGN Fundamental Data Overview February 03, 2026

P/S = 22642.0122
P/B = 3.0148
Revenue TTM = 588.0k USD
EBIT TTM = -73.2m USD
EBITDA TTM = -72.6m USD
Long Term Debt = 1.74m USD (from capitalLeaseObligations, last quarter)
Short Term Debt = 866.0k USD (from shortTermDebt, last quarter)
Debt = 1.74m USD (from shortLongTermDebtTotal, last quarter)
Net Debt = -13.3m USD (from netDebt column, last quarter)
Enterprise Value = 377.4m USD (581.6m + Debt 1.74m - CCE 206.0m)
Interest Coverage Ratio = -12.74 (Ebit TTM -73.2m / Interest Expense TTM -5.75m)
EV/FCF = -7.20x (Enterprise Value 377.4m / FCF TTM -52.4m)
FCF Yield = -13.89% (FCF TTM -52.4m / Enterprise Value 377.4m)
FCF Margin = -8913 % (FCF TTM -52.4m / Revenue TTM 588.0k)
Net Margin = -11.5k% (Net Income TTM -67.4m / Revenue TTM 588.0k)
Gross Margin = unknown ((Revenue TTM 588.0k - Cost of Revenue TTM 15.0m) / Revenue TTM)
Tobins Q-Ratio = 1.78 (Enterprise Value 377.4m / Total Assets 211.8m)
Interest Expense / Debt = 7.40% (Interest Expense 129.0k / Debt 1.74m)
Taxrate = 21.0% (US default 21%)
NOPAT = -57.8m (EBIT -73.2m * (1 - 21.00%)) [loss with tax shield]
Current Ratio = 18.71 (Total Current Assets 209.0m / Total Current Liabilities 11.2m)
Debt / Equity = 0.01 (Debt 1.74m / totalStockholderEquity, last quarter 199.7m)
Debt / EBITDA = 0.18 (negative EBITDA) (Net Debt -13.3m / EBITDA -72.6m)
Debt / FCF = 0.25 (negative FCF - burning cash) (Net Debt -13.3m / FCF TTM -52.4m)
Total Stockholder Equity = 220.7m (last 4 quarters mean from totalStockholderEquity)
RoA = -28.49% (Net Income -67.4m / Total Assets 211.8m)
RoE = -30.56% (Net Income TTM -67.4m / Total Stockholder Equity 220.7m)
RoCE = -32.90% (EBIT -73.2m / Capital Employed (Equity 220.7m + L.T.Debt 1.74m))
RoIC = -26.20% (negative operating profit) (NOPAT -57.8m / Invested Capital 220.7m)
WACC = 9.50% (E(581.6m)/V(583.3m) * Re(9.51%) + D(1.74m)/V(583.3m) * Rd(7.40%) * (1-Tc(0.21)))
Discount Rate = 9.51% (= CAPM, Blume Beta Adj.)
Shares Correlation 3-Years: 100.0 | Cagr: 0.71%
Fair Price DCF = unknown (Cash Flow -52.4m)
EPS Correlation: 37.57 | EPS CAGR: 29.38% | SUE: 4.0 | # QB: 1
Revenue Correlation: 17.73 | Revenue CAGR: 0.0% | SUE: 0.0 | # QB: 0
EPS next Quarter (2026-03-31): EPS=-0.35 | Chg30d=-0.010 | Revisions Net=+1 | Analysts=4
EPS next Year (2026-12-31): EPS=-1.30 | Chg30d=+0.016 | Revisions Net=-1 | Growth EPS=+0.5% | Growth Revenue=+0.0%

Additional Sources for DSGN Stock

News: Wall Street Journal | Benzinga | Yahoo Finance
Fund Manager Positions: Dataroma | Stockcircle