EXEL Stock Analysis: Exelixis | NASDAQ

Biotechnology | NASDAQ, USA | Market Cap: 14.582m USD | 12M Return: 55.2% | US30161Q1040 | Charts, Fundamentals & Technical Analysis

Total Rating 76
Safety 91
Buy Signal 1.09
Biotechnology
Industry Rotation: -19.5
Market Cap: 14.6B
Avg Turnover: 122M
Risk 3d forecast
Volatility37.3%
VaR 5th Pctl5.36%
VaR vs Median-9.57%
Reward TTM
Sharpe Ratio1.27
Rel. Str. IBD85.2
Rel. Str. Peer Group70.3
Character TTM
Beta0.875
Beta Downside0.156
Hurst Exponent0.331
Drawdowns 3y
Max DD25.34%
CAGR/Max DD1.64
CAGR/Mean DD6.50
EPS (Earnings per Share) EPS (Earnings per Share) of EXEL over the last years for every Quarter: "2021-09": 0.2, "2021-12": 0.35, "2022-03": 0.26, "2022-06": 0.28, "2022-09": 0.31, "2022-12": -0.03, "2023-03": 0.16, "2023-06": 0.31, "2023-09": 0.1, "2023-12": 0.33, "2024-03": 0.17, "2024-06": 0.84, "2024-09": 0.47, "2024-12": 0.55, "2025-03": 0.62, "2025-06": 0.75, "2025-09": 0.78, "2025-12": 0.94, "2026-03": 0.87, "2026-06": 0.82,
EPS CAGR: 87.14%
EPS Trend: 95.0%
Last SUE: 0.50
Qual. Beats: 0
Revenue Revenue of EXEL over the last years for every Quarter: 2021-09: 328.423, 2021-12: 451.14, 2022-03: 355.98, 2022-06: 419.427, 2022-09: 411.738, 2022-12: 423.917, 2023-03: 408.788, 2023-06: 469.848, 2023-09: 471.92, 2023-12: 479.652, 2024-03: 425.226, 2024-06: 637.178, 2024-09: 539.542, 2024-12: 566.755, 2025-03: 555.447, 2025-06: 568.261, 2025-09: 597.755, 2025-12: 598.663, 2026-03: 610.812, 2026-06: 628.69,
Rev. CAGR: 12.36%
Rev. Trend: 96.3%
Last SUE: -0.03
Qual. Beats: 0

Warnings

No concerns identified

Tailwinds

Shakeout

Seasonality 11.7 years of data

Jan -1.4% 19
Feb +0.1% 7
Mar +4.9% 8
Apr -1.8% 8
May +0.3% 7
Jun +2.8% 19
Jul -2.0% 19
Aug -0.3% 5
Sep -3.0% 14
Oct -7.9% 40
Nov +5.2% 42
Dec +2.5% 12

How good or bad each month usually is (without trend). The score below shows how much you can trust it: 0 = pure chance, >40 gets interesting and >55 is strong.

Description: EXEL Exelixis

Exelixis, Inc. is a U.S.-based oncology biopharmaceutical company headquartered in Alameda, California, focused on discovering, developing, and commercializing treatments for difficult-to-treat cancers. The companys commercial portfolio is anchored by CABOMETYX and COMETRIQ, both derived from its lead compound cabozantinib, an inhibitor of multiple tyrosine kinases including MET, AXL, RET, and VEGF receptors. Additional marketed products include COTELLIC, a MEK inhibitor used in combination therapy for advanced melanoma, and MINNEBRO, a mineralocorticoid receptor blocker for hypertension that is sold in Japan through a partner.

Beyond its approved medicines, Exelixis maintains a pipeline of oncology therapies in earlier stages of development, including zanzalintinib (an oral kinase inhibitor), XL309 (a USP1 inhibitor targeting BRCA-mutated tumors), and several antibody-drug conjugates and bispecific antibody candidates such as XB010, XB628, and XB371. The company operates a hybrid business model common to mid-to-large biotechnology firms, combining direct commercialization of its lead products in the United States with licensing and collaboration agreements covering international markets. It has research, development, and commercialization partnerships with major pharmaceutical companies including Ipsen, Takeda, Roche/Genentech, Bristol-Myers Squibb, and Daiichi Sankyo, which extend the reach of its approved products and support pipeline development. Exelixis was incorporated in 1994 and completed its IPO in 2000.

Headlines to Watch Out For
  • CABOMETYX franchise revenue growth sustains US oncology sales
  • Zanzalintinib and ADC pipeline readouts diversify beyond cabozantinib
  • Renal cell carcinoma competition intensifies from IO-TKI combinations
Piotroski VR-10 (Strict) 6.5
Net Income: 860.6m TTM > 0 and > 6% of Revenue
FCF/TA: 0.46 > 0.02 and ΔFCF/TA 19.44 > 1.0
NWC/Revenue: 36.49% < 20% (prev 37.88%; Δ -1.39% < -1%)
CFO/TA 0.47 > 3% & CFO 1.18b > Net Income 860.6m
Net Debt (-673.5m) to EBITDA (1.03b): -0.65 < 3
Current Ratio: 3.46 > 1.5 & < 3
Outstanding Shares: last quarter (259.7m) vs 12m ago -8.69% < -2%
Gross Margin: error (current vs previous; cannot be calculated due to missing/invalid data or negative margin)
Asset Turnover: 94.19% > 50% (prev 83.27%; Δ 10.92% > 0%)
Interest Coverage Ratio: error (cannot be calculated; needs correct EBIT TTM and Interest Expense TTM)
Altman Z'' 7.58
A: 0.36 (Total Current Assets 1.25b - Total Current Liabilities 361.9m) / Total Assets 2.49b
B: -0.11 (Retained Earnings -262.5m / Total Assets 2.49b)
C: 0.39 (EBIT TTM 1.00b / Avg Total Assets 2.59b)
D: 2.83 (Book Value of Equity 1.84b / Total Liabilities 650.5m)
Altman-Z'' = 7.58 = AAA
Beneish M -2.99
DSRI: 1.05 (Receivables 334.6m/292.4m, Revenue 2.44b/2.23b)
GMI: 1.00 (GM 96.59% / 96.48%)
AQI: 0.90 (AQ_t 0.36 / AQ_t-1 0.40)
SGI: 1.09 (Revenue 2.44b / 2.23b)
TATA: -0.13 (NI 860.6m - CFO 1.18b) / TA 2.49b)
Beneish M = -2.99 (Cap -4..+1) = A
What is the price of EXEL shares?

As of October 10, 2026, the stock is trading at USD 59.86 with a total of 2,665,498 shares traded. Over the past week, the price has changed by +2.52%, over one month by +2.62%, over three months by +4.83% and over the past year by +55.20%.

Current recommended Stop Loss: 55.40 (which is 7.5% or 2.6 ATR below the current price).

Is EXEL a buy, sell or hold?

Exelixis has received a consensus analysts rating of 3.67. Therefore, it is recommended to hold EXEL.

  • StrongBuy: 6
  • Buy: 1
  • Hold: 10
  • Sell: 1
  • StrongSell: 0

What are the forecasts/targets for the EXEL price?
Analysts Target Price 53.9 -9.9%
Exelixis (EXEL) - Fundamental Data Overview as of 07 October 2026
Market Cap USD = 14.6b (14.6b USD * 1.0 USD.USD)
P/E Trailing = 18.5647
P/E Forward = 13.5501
P/S = 5.9862
P/B = 7.8154
P/EG = 2.2685
Revenue TTM = 2.44b USD
EBIT TTM = 1.00b USD
EBITDA TTM = 1.03b USD
 Long Term Debt = unknown (none)
 Short Term Debt = unknown (none)
 Debt = 165.9m USD (from shortLongTermDebtTotal, last quarter) (leases 165.9m already included)
Net Debt = -673.5m USD (calculated: Debt 165.9m - CCE 839.4m)
Enterprise Value = 13.9b USD (14.6b + Debt 165.9m - CCE 839.4m)
 Interest Coverage Ratio = unknown (Ebit TTM 1.00b / Interest Expense TTM 0.0)
 EV/FCF = 12.01x (Enterprise Value 13.9b / FCF TTM 1.16b)
FCF Yield = 8.33% (FCF TTM 1.16b / Enterprise Value 13.9b)
FCF Margin = 47.55% (FCF TTM 1.16b / Revenue TTM 2.44b)
Net Margin = 35.33% (Net Income TTM 860.6m / Revenue TTM 2.44b)
 Gross Margin = unknown ((Revenue TTM 2.44b - Cost of Revenue TTM 85.7m) / Revenue TTM)
 Tobins Q-Ratio = 5.58 (Enterprise Value 13.9b / Total Assets 2.49b)
Interest Expense / Debt = 0.0% (Interest Expense 0.0 / Debt 165.9m)
Taxrate = 16.89% (174.8m / 1.04b)
NOPAT = 834.8m (EBIT 1.00b * (1 - 16.89%))
Current Ratio = 3.46 (Total Current Assets 1.25b / Total Current Liabilities 361.9m)
Debt / Equity = 0.09 (Debt 165.9m / totalStockholderEquity, last quarter 1.84b)
Debt / EBITDA = -0.65 (Net Debt -673.5m / EBITDA 1.03b)
Debt / FCF = -0.58 (Net Debt -673.5m / FCF TTM 1.16b)
Total Stockholder Equity = 2.03b (last 4 quarters mean from totalStockholderEquity)
RoA = 33.28% (Net Income 860.6m / Total Assets 2.49b)
RoE = 42.49% (Net Income TTM 860.6m / Total Stockholder Equity 2.03b)
RoCE = 47.11% (EBIT 1.00b / Capital Employed (Total Assets 2.49b - Current Liab 361.9m))
RoIC = 41.52% (NOPAT 834.8m / Invested Capital 2.01b)
WACC = 8.96% (E(14.6b)/V(14.7b) * Re(9.06%) + D(165.9m)/V(14.7b) * Rd(0.0%) * (1-Tc(0.17)))
Discount Rate = 9.06% (= CAPM, Blume Beta Adj.)
Shares (quarterly) Correlation: -92.66 | Cagr: -6.97%
[DCF] Terminal Value 76.02% ; FCFF base≈984.0m ; Y1≈1.13b ; Y5≈1.66b
[DCF] Fair Price = 93.80 (EV 22.6b - Net Debt -673.5m = Equity 23.2b / Shares 247.8m; r=8.96% [WACC]; 5y FCF grow 15.0% → 2.50% )
EPS Correlation: 95.02 | EPS CAGR: 87.14% | SUE: 0.50 | # QB: 0
Revenue Correlation: 96.27 | Revenue CAGR: 12.36% | SUE: -0.03 | # QB: 0
EPS current Quarter (2026-09-30): EPS=0.90 | Chg30d=-0.66% | Revisions=+25% | Analysts=9
EPS current Year (2026-12-31): EPS=3.59 | Chg30d=+0.17% | Revisions=+8% | GrowthEPS=+16.5% | GrowthRev=+10.1%
EPS next Year (2027-12-31): EPS=4.25 | Chg30d=-0.14% | Revisions=-7% | GrowthEPS=+18.6% | GrowthRev=+13.8%
[Analyst] Revisions Ratio: +9% (up=16, down=13)