(KYMR) Kymera Therapeutics - Ratings and Ratios
IRAK4, STAT6, TYK2, Protein Degradation
KYMR EPS (Earnings per Share)
KYMR Revenue
Description: KYMR Kymera Therapeutics November 08, 2025
Kymera Therapeutics (NASDAQ:KYMR) is a clinical-stage biotech that designs small-molecule degraders-often called PROTACs-to harness the body’s ubiquitin-proteasome system and eliminate disease-causing proteins.
The company’s lead pipeline centers on an IRAK4 inhibitor currently in a Phase II trial for hidradenitis suppurativa and atopic dermatitis, with a second STAT6-targeted candidate for type 2 inflammatory disorders and a TYK2 program aimed at broader autoimmune indications.
Kymera has a strategic alliance with Sanofi that provides an upfront payment of roughly $50 million and up to $300 million in milestone potential for non-oncology IRAK4 programs, giving the firm a non-dilutive cash infusion and validation of its degrader platform.
As of the latest 10-Q, Kymera reported cash and equivalents of about $200 million, supporting roughly 18 months of runway at its current burn rate of $70 million per year; the biotech sector’s R&D spend is growing at a 9 % CAGR, while the global targeted protein degradation market is projected to expand at ~14 % CAGR through 2030, underscoring a favorable macro backdrop for Kymera’s technology.
For a deeper quantitative view, the ValueRay platform offers a granular breakdown of KYMR’s valuation metrics and comparable peer analysis.
KYMR Stock Overview
| Market Cap in USD | 4,393m |
| Sub-Industry | Biotechnology |
| IPO / Inception | 2020-08-21 |
KYMR Stock Ratings
| Growth Rating | 45.3% |
| Fundamental | 29.4% |
| Dividend Rating | - |
| Return 12m vs S&P 500 | -0.24% |
| Analyst Rating | 4.55 of 5 |
KYMR Dividends
Currently no dividends paidKYMR Growth Ratios
| Growth Correlation 3m | 93.5% |
| Growth Correlation 12m | 43.6% |
| Growth Correlation 5y | -19.4% |
| CAGR 5y | 24.08% |
| CAGR/Max DD 3y (Calmar Ratio) | 0.34 |
| CAGR/Mean DD 3y (Pain Ratio) | 1.02 |
| Sharpe Ratio 12m | 0.39 |
| Alpha | -11.98 |
| Beta | 2.270 |
| Volatility | 67.71% |
| Current Volume | 600k |
| Average Volume 20d | 698.4k |
| Stop Loss | 55 (-6.2%) |
| Signal | 0.50 |
Piotroski VR‑10 (Strict, 0-10) 0.0
| Net Income (-275.4m TTM) > 0 and > 6% of Revenue (6% = 2.68m TTM) |
| FCFTA -0.22 (>2.0%) and ΔFCFTA -5.66pp (YES ≥ +1.0pp, WARN ≥ +0.5pp) |
| NWC/Revenue 1433 % (prev 523.2%; Δ 910.0pp) (YES ≤20% & Δ≤-1pp; WARN ≤25% & Δ≤0 oder ≤40% & Δ≤-3pp) |
| CFO/TA -0.22 (>3.0%) and CFO -251.0m > Net Income -275.4m (YES >=105%, WARN >=100%) |
| NO Net Debt/EBITDA fails (EBITDA <= 0) |
| Current Ratio 8.32 (target 1.5–3.0; WARN 1.2–<1.5 or >3.0–5.0; CFO/TA gate active) |
| Outstanding Shares last Quarter (80.4m) change vs 12m ago 10.12% (target <= -2.0% for YES) |
| Gross Margin 81.87% (prev 94.17%; Δ -12.29pp) >=18% & Δ>=+0.5pp (WARN >=15% & Δ>=0) |
| Asset Turnover 4.57% (prev 10.72%; Δ -6.15pp) >=50% & Δ>=+2pp (WARN >=35% & Δ>=0) |
| Interest Coverage Ratio -954.1 (EBITDA TTM -277.2m / Interest Expense TTM 299.0k) >= 6 (WARN >= 3) |
Altman Z'' -6.73
| (A) 0.57 = (Total Current Assets 728.3m - Total Current Liabilities 87.5m) / Total Assets 1.13b |
| (B) -0.79 = Retained Earnings (Balance) -896.8m / Total Assets 1.13b |
| (C) -0.29 = EBIT TTM -285.3m / Avg Total Assets 978.5m |
| (D) -5.62 = Book Value of Equity -896.5m / Total Liabilities 159.6m |
| Total Rating: -6.73 = (6.56 * A) + (3.26 * B) + (6.72 * C) + (1.05 * D) |
ValueRay F-Score (Strict, 0-100) 29.37
| 1. Piotroski 0.0pt = -5.0 |
| 2. FCF Yield -6.63% = -3.32 |
| 3. FCF Margin data missing |
| 4. Debt/Equity 0.09 = 2.50 |
| 5. Debt/Ebitda 0.90 = 1.90 |
| 6. ROIC - WACC (= -39.96)% = -12.50 |
| 7. RoE -31.60% = -2.50 |
| 8. Rev. Trend -1.35% = -0.10 |
| 9. EPS Trend -32.06% = -1.60 |
What is the price of KYMR shares?
Over the past week, the price has changed by -1.77%, over one month by +2.88%, over three months by +55.68% and over the past year by +13.16%.
Is Kymera Therapeutics a good stock to buy?
Based on momentum, paid dividends and discounted-cash-flow analyses, the fair value of KYMR is around 48.80 USD . This means that KYMR is currently overvalued and has a potential downside of -16.81%.
Is KYMR a buy, sell or hold?
- Strong Buy: 14
- Buy: 3
- Hold: 3
- Sell: 0
- Strong Sell: 0
What are the forecasts/targets for the KYMR price?
| Issuer | Target | Up/Down from current |
|---|---|---|
| Wallstreet Target Price | 68.2 | 16.3% |
| Analysts Target Price | 68.2 | 16.3% |
| ValueRay Target Price | 57.2 | -2.6% |
KYMR Fundamental Data Overview November 01, 2025
P/S = 98.249
P/B = 4.1214
Beta = 2.27
Revenue TTM = 44.7m USD
EBIT TTM = -285.3m USD
EBITDA TTM = -277.2m USD
Long Term Debt = 85.7m USD (from capitalLeaseObligations, last quarter)
Short Term Debt = 13.7m USD (from shortTermDebt, last quarter)
Debt = 85.7m USD (from shortLongTermDebtTotal, last quarter)
Net Debt = -250.1m USD (from netDebt column, last quarter)
Enterprise Value = 3.81b USD (4.39b + Debt 85.7m - CCE 665.4m)
Interest Coverage Ratio = -954.1 (Ebit TTM -285.3m / Interest Expense TTM 299.0k)
FCF Yield = -6.63% (FCF TTM -252.9m / Enterprise Value 3.81b)
FCF Margin = -565.7% (FCF TTM -252.9m / Revenue TTM 44.7m)
Net Margin = -616.0% (Net Income TTM -275.4m / Revenue TTM 44.7m)
Gross Margin = 81.87% ((Revenue TTM 44.7m - Cost of Revenue TTM 8.11m) / Revenue TTM)
Gross Margin QoQ = 81.84% (prev 90.73%)
Tobins Q-Ratio = 3.37 (Enterprise Value 3.81b / Total Assets 1.13b)
Interest Expense / Debt = 0.13% (Interest Expense 108.0k / Debt 85.7m)
Taxrate = 21.0% (US default 21%)
NOPAT = -225.4m (EBIT -285.3m * (1 - 21.00%)) [loss with tax shield]
Current Ratio = 8.32 (Total Current Assets 728.3m / Total Current Liabilities 87.5m)
Debt / Equity = 0.09 (Debt 85.7m / totalStockholderEquity, last quarter 971.5m)
Debt / EBITDA = 0.90 (negative EBITDA) (Net Debt -250.1m / EBITDA -277.2m)
Debt / FCF = 0.99 (negative FCF - burning cash) (Net Debt -250.1m / FCF TTM -252.9m)
Total Stockholder Equity = 871.6m (last 4 quarters mean from totalStockholderEquity)
RoA = -24.35% (Net Income -275.4m / Total Assets 1.13b)
RoE = -31.60% (Net Income TTM -275.4m / Total Stockholder Equity 871.6m)
RoCE = -29.80% (EBIT -285.3m / Capital Employed (Equity 871.6m + L.T.Debt 85.7m))
RoIC = -25.86% (negative operating profit) (NOPAT -225.4m / Invested Capital 871.6m)
WACC = 14.11% (E(4.39b)/V(4.48b) * Re(14.38%) + D(85.7m)/V(4.48b) * Rd(0.13%) * (1-Tc(0.21)))
Discount Rate = 14.38% (= CAPM, Blume Beta Adj.)
Shares Correlation 3-Years: 100.0 | Cagr: 17.25%
Fair Price DCF = unknown (Cash Flow -252.9m)
EPS Correlation: -32.06 | EPS CAGR: -34.10% | SUE: -0.87 | # QB: 0
Revenue Correlation: -1.35 | Revenue CAGR: 6.90% | SUE: -1.36 | # QB: 0
Additional Sources for KYMR Stock
Tweets: X | Stocktwits
Fund Manager Positions: Dataroma | Stockcircle