MGTX Stock Analysis: MeiraGTx Holdings | NASDAQ

Biotechnology | NASDAQ, USA | Market Cap: 1.228m USD | 12M Return: 78% | KYG596651029 | Charts, Fundamentals & Technical Analysis

Gene Therapy, Ocular Treatments, Neurodegenerative Therapies, Cell Therapy
Total Rating 72
Safety 32
Buy Signal 0.15
Biotechnology
Industry Rotation: -3.5
Market Cap: 1.23B
Avg Turnover: 10.0M
Risk 3d forecast
Volatility60.9%
VaR 5th Pctl10.0%
VaR vs Median-0.11%
Reward TTM
Sharpe Ratio1.19
Rel. Str. IBD93.3
Rel. Str. Peer Group70.8
Character TTM
Beta1.606
Beta Downside1.353
Hurst Exponent0.550
Drawdowns 3y
Max DD47.07%
CAGR/Max DD0.78
CAGR/Mean DD2.05
EPS (Earnings per Share) EPS (Earnings per Share) of MGTX over the last years for every Quarter: "2021-09": -0.59, "2021-12": -0.22, "2022-03": -0.7, "2022-06": -0.76, "2022-09": -0.83, "2022-12": -0.6, "2023-03": -0.62, "2023-06": -0.53, "2023-09": -0.74, "2023-12": -0.42, "2024-03": -0.77, "2024-06": -0.76, "2024-09": -0.55, "2024-12": -0.5, "2025-03": -0.51, "2025-06": -0.48, "2025-09": -0.62, "2025-12": 0.19, "2026-03": -0.57, "2026-06": 1.71,
Last SUE: 4.00
Qual. Beats: 1
Revenue Revenue of MGTX over the last years for every Quarter: 2021-09: 6.947, 2021-12: 21.043, 2022-03: 5.633, 2022-06: 10.759, 2022-09: 4.816, 2022-12: -5.288, 2023-03: 3.334, 2023-06: 3.54, 2023-09: 5.103, 2023-12: 2.04, 2024-03: 0.697, 2024-06: 0.282, 2024-09: 10.91, 2024-12: 21.39, 2025-03: 1.926, 2025-06: 3.691, 2025-09: 0.41, 2025-12: 75.364, 2026-03: 0.293, 2026-06: 321.434,
Rev. CAGR: 221.39%
Rev. Trend: 90.8%
Last SUE: 4.00
Qual. Beats: 1

Warnings

Earnings Expected To Drop (P/E To P/E Forward)
Strong Share Dilution
Beneish M-Score Likely Earnings Manipulation
Below Avwap Earnings

Tailwinds

Rs Leader
Confidence

Seasonality 8.1 years of data

Jan -6.2% 23
Feb +1.4% 9
Mar -4.8% 24
Apr +1.7% 21
May +2.4% 9
Jun +3.9% 0
Jul +3.4% 2
Aug -8.2% 10
Sep +3.1% 26
Oct -3.8% 6
Nov +9.4% 7
Dec +6.2% 10

How good or bad each month usually is (without trend). The score below shows how much you can trust it: 0 = pure chance, >40 gets interesting and >55 is strong.

Description: MGTX MeiraGTx Holdings

MeiraGTx Holdings plc is a clinical-stage genetic medicines company developing gene therapies for serious diseases, with its lead programs targeting ocular disorders, neurodegenerative conditions, and xerostomia. Its clinical pipeline spans multiple Phase 1/2 and Phase 2 trials-including AAV-AQP1 for radiation-induced xerostomia and Sjogrens syndrome, AAV-GAD for Parkinsons disease, AAV-RPE65 for RPE65-associated retinal dystrophy, and AAV-CNGB3/AAV-CNGA3 for achromatopsia-while preclinical work addresses additional inherited retinal diseases, amyotrophic lateral sclerosis, Alzheimers disease, and age-related macular degeneration. The company also operates a riboswitch platform for metabolic peptide delivery and a cell therapy program aimed at oncology, autoimmune disease, and intractable pain.

The business model relies on a partnership-driven approach, with notable collaborations including Johnson & Johnson Innovative Medicine for inherited retinal disease gene therapies and Hologen Limited for CNS-focused programs such as AAV-GAD (Parkinsons) and AAV-BDNF (genetic obesity). Founded in 2015 and headquartered in New York, MeiraGTx is classified within the Biotechnology sub-industry, a sector where pre-revenue companies typically depend on capital raises, milestone payments, and strategic alliances to fund costly late-stage clinical development before reaching commercialization.

Headlines to Watch Out For
  • Johnson & Johnson partnership catalyzes retinal gene therapy milestones
  • Phase 2 readouts pending across AAV-AQP1 xerostomia and AAV-GAD Parkinson programs
  • In-house GMP manufacturing supports clinical supply and partnership economics
Piotroski VR-10 (Strict) 4.5
Net Income: 79.0m TTM > 0 and > 6% of Revenue
FCF/TA: 0.02 > 0.02 and ΔFCF/TA 69.01 > 1.0
NWC/Revenue: 40.31% < 20% (prev -16.75%; Δ 57.07% < -1%)
CFO/TA 0.03 > 3% & CFO 13.7m > Net Income 79.0m
Net Debt (-18.5m) to EBITDA (196.2m): -0.09 < 3
Current Ratio: 3.76 > 1.5 & < 3
Outstanding Shares: last quarter (93.8m) vs 12m ago 16.40% < -2%
Gross Margin: error (current vs previous; cannot be calculated due to missing/invalid data or negative margin)
Asset Turnover: 133.6% > 50% (prev 19.08%; Δ 114.5% > 0%)
Interest Coverage Ratio: 14.75 > 6 (EBIT TTM 184.0m / Interest Expense TTM 12.5m)
Altman Z'' 2.29
A: 0.40 (Total Current Assets 218.3m - Total Current Liabilities 58.1m) / Total Assets 396.4m
B: -1.77 (Retained Earnings -701.8m / Total Assets 396.4m)
C: 0.62 (EBIT TTM 184.0m / Avg Total Assets 297.6m)
D: 1.19 (Book Value of Equity 215.6m / Total Liabilities 180.7m)
Altman-Z'' = 2.29 = BBB
Beneish M 1.00
DSRI: 0.62 (Receivables 44.3m/6.79m, Revenue 397.5m/37.9m)
GMI: 0.27 (GM 26.56% / 97.19%)
AQI: 2.03 (AQ_t 0.11 / AQ_t-1 0.05)
SGI: 10.48 (Revenue 397.5m / 37.9m)
TATA: 0.16 (NI 79.0m - CFO 13.7m) / TA 396.4m)
Beneish M = 3.43 (Cap -4..+1) = D
What is the price of MGTX shares?

As of September 18, 2026, the stock is trading at USD 13.05 with a total of 953,000 shares traded. Over the past week, the price has changed by +1.56%, over one month by -5.23%, over three months by +25.36% and over the past year by +78.04%.

Current recommended Stop Loss: 12.10 (which is 7.3% or 1.6 ATR below the current price).

Is MGTX a buy, sell or hold?

MeiraGTx Holdings has received a consensus analysts rating of 4.60. Therefore, it is recommended to buy MGTX.

  • StrongBuy: 3
  • Buy: 2
  • Hold: 0
  • Sell: 0
  • StrongSell: 0

What are the forecasts/targets for the MGTX price?
Analysts Target Price 29.4 125.5%
MeiraGTx Holdings (MGTX) - Fundamental Data Overview as of 14 September 2026
Market Cap USD = 1.23b (1.23b USD * 1.0 USD.USD)
P/E Trailing = 14.7011
P/E Forward = 64.1026
P/S = 3.0903
P/B = 5.7005
Revenue TTM = 397.5m USD
EBIT TTM = 184.0m USD
EBITDA TTM = 196.2m USD
Long Term Debt = 100.0m USD (from longTermDebt, last quarter)
Short Term Debt = 2.30m USD (from shortTermDebt, last quarter)
Debt = 124.6m USD (from shortLongTermDebtTotal, last quarter) + Leases 12.3m
Net Debt = -18.5m USD (calculated: Debt 124.6m - CCE 143.2m)
Enterprise Value = 1.21b USD (1.23b + Debt 124.6m - CCE 143.2m)
Interest Coverage Ratio = 14.75 (Ebit TTM 184.0m / Interest Expense TTM 12.5m)
EV/FCF = 191.8x (Enterprise Value 1.21b / FCF TTM 6.31m)
FCF Yield = 0.52% (FCF TTM 6.31m / Enterprise Value 1.21b)
FCF Margin = 1.59% (FCF TTM 6.31m / Revenue TTM 397.5m)
Net Margin = 19.87% (Net Income TTM 79.0m / Revenue TTM 397.5m)
 Gross Margin = unknown ((Revenue TTM 397.5m - Cost of Revenue TTM 11.2m) / Revenue TTM)
 Tobins Q-Ratio = 3.05 (Enterprise Value 1.21b / Total Assets 396.4m)
Interest Expense / Debt = 10.01% (Interest Expense 12.5m / Debt 124.6m)
Taxrate = 1.45% (2.36m / 163.0m)
NOPAT = 181.4m (EBIT 184.0m * (1 - 1.45%))
Current Ratio = 3.76 (Total Current Assets 218.3m / Total Current Liabilities 58.1m)
Debt / Equity = 0.58 (Debt 124.6m / totalStockholderEquity, last quarter 215.6m)
Debt / EBITDA = -0.09 (Net Debt -18.5m / EBITDA 196.2m)
Debt / FCF = -2.94 (Net Debt -18.5m / FCF TTM 6.31m)
Total Stockholder Equity = 27.8m (last 4 quarters mean from totalStockholderEquity)
RoA = 26.54% (Net Income 79.0m / Total Assets 396.4m)
RoE = 284.4% (Net Income TTM 79.0m / Total Stockholder Equity 27.8m)
RoCE = 144.0% (EBIT 184.0m / Capital Employed (Equity 27.8m + L.T.Debt 100.0m))
RoIC = 56.54% (NOPAT 181.4m / Invested Capital 320.8m)
WACC = 11.47% (E(1.23b)/V(1.35b) * Re(11.63%) + D(124.6m)/V(1.35b) * Rd(10.01%) * (1-Tc(0.01)))
Discount Rate = 11.63% (= CAPM, Blume Beta Adj.)
Shares (quarterly) Correlation: 93.77 | Cagr: 18.47%
[DCF] Terminal Value 65.33% ; FCFF base≈6.31m ; Y1≈6.34m ; Y5≈6.71m
[DCF] Fair Price = 0.90 (EV 68.2m - Net Debt -18.5m = Equity 86.7m / Shares 96.0m; r=11.47% [WACC]; 5y FCF grow 0.0% → 2.50% )
EPS Correlation: N/A | EPS CAGR: N/A | SUE: 4.0 | # QB: 1
Revenue Correlation: 90.79 | Revenue CAGR: 221.4% | SUE: 4.0 | # QB: 1
EPS current Quarter (2026-09-30): EPS=-0.46 | Chg30d=+6.76% | Revisions=+40% | Analysts=2
EPS current Year (2026-12-31): EPS=0.51 | Chg30d=+135.37% | Revisions=+40% | GrowthEPS=+135.9% | GrowthRev=+314.7%
EPS next Year (2027-12-31): EPS=-1.39 | Chg30d=-1.70% | Revisions=+40% | GrowthEPS=-372.5% | GrowthRev=-80.0%
[Analyst] Revisions Ratio: +67% (up=6, down=0)