ODTX Stock Analysis: Odyssey Therapeutics | NASDAQ

Biotechnology | NASDAQ, USA | Market Cap: 807m USD | 12M Return: -3.1% | Charts, Fundamentals & Technical Analysis

Autoimmune Therapies, Inflammatory Treatments, Small Molecules, Protein Therapeutics
Total Rating 18
Safety 36
Buy Signal -1.04
Biotechnology
Industry Rotation: +30.9
Market Cap: 807M
Avg Turnover: 5.82M
Risk 3d forecast
Volatility66.0%
VaR 5th Pctl13.9%
VaR vs Median16.0%
Reward TTM
Sharpe Ratio-1.13
Rel. Str. IBD19.8
Rel. Str. Peer Group9.8
Character TTM
Beta
Beta Downside
Hurst Exponent0.520
Drawdowns 3y
Max DD16.57%
CAGR/Max DD-3.26
CAGR/Mean DD-11.26
EPS (Earnings per Share) EPS (Earnings per Share) of ODTX over the last years for every Quarter: "2022-12": null, "2023-12": null, "2024-12": null, "2025-03": null, "2025-12": null, "2026-03": -6.7459,
Revenue Revenue of ODTX over the last years for every Quarter: 2022-12: 0, 2023-12: 1.037, 2024-12: 1.755, 2025-03: 1.918, 2025-12: 2.976, 2026-03: 0,
Rev. CAGR: 69.41%
Rev. Trend: 69.9%
Qual. Beats: 0

Warnings

Negative Equity With Losses: Insolvent Profile
Interest Coverage Ratio Critical
Altman Z'' In Financial Distress Zone
Below Avwap Earnings
Below Sma 200d

Tailwinds

No distinct edge detected

Seasonality 0.1 years of data

Jan - -
Feb - -
Mar - -
Apr - -
May - -
Jun - -
Jul - -
Aug - -
Sep - -
Oct - -
Nov - -
Dec - -

How good or bad each month usually is (without trend). The score below shows how much you can trust it: 0 = pure chance, >40 gets interesting and >55 is strong.

Description: ODTX Odyssey Therapeutics

Odyssey Therapeutics, Inc. (NASDAQ: ODTX) is a clinical-stage biopharmaceutical company headquartered in Boston, Massachusetts, that develops medicines for autoimmune and inflammatory diseases. The company was incorporated in 2021 and operates from the Boston/Cambridge biotech cluster, a major hub for immunology research and biopharma venture funding.

Its pipeline is built around small-molecule and protein-based candidates targeting innate immune and inflammatory pathways. The lead asset, OD-001, is an oral small-molecule inhibitor of RIPK2 currently in a Phase 2a trial for ulcerative colitis. Additional programs include OD-002, an oral SLC15A4 inhibitor aimed at blocking TLR7/8/9-driven IRF5 activation; OD-003, a protein therapeutic designed to selectively agonize TNFR2 on regulatory T cells; a TSLP/IL-33 bispecific antagonist; an oral small-molecule IRAK4 scaffolding inhibitor; and a small-molecule IRF5 inhibitor.

As a clinical-stage biotechnology company, Odyssey does not yet have approved products or commercial revenue, and its operations are funded primarily through capital markets and R&D partnerships. Autoimmune and inflammatory diseases remain a large and active therapeutic area, with several kinase and innate-immune targets (such as IRAK4, RIPK2, and IRF5) being pursued by multiple drug developers.

Headlines to Watch Out For
  • OD-001 Phase 2a ulcerative colitis data readout approaches
  • Cash burn accelerates as clinical trials expand across pipeline
  • Big pharma partnership or acquisition interest in inflammation assets
Piotroski VR-10 (Strict) 1.0
Net Income: -76.7m TTM > 0 and > 6% of Revenue
FCF/TA: -0.30 > 0.02 and ΔFCF/TA 29.45 > 1.0
NWC/Revenue: 8.49k% < 20% (prev 2.39k%; Δ 6.10k% < -1%)
CFO/TA -0.35 > 3% & CFO -79.7m > Net Income -76.7m
Net Debt/EBITDA: error (EBITDA <= 0)
Current Ratio: 8.33 > 1.5 & < 3
Outstanding Shares: last fiscal year (27.6m) vs prev -41.58% < -2%
Gross Margin: error (current vs previous; cannot be calculated due to missing/invalid data or negative margin)
Asset Turnover: 0.90% > 50% (prev 2.27%; Δ -1.37% > 0%)
Interest Coverage Ratio: -7.05k > 6 (EBIT TTM -84.6m / Interest Expense TTM 12.0k)
Altman Z'' -7.36
A: 0.71 (Total Current Assets 185.1m - Total Current Liabilities 22.2m) / Total Assets 229.1m
B: -2.65 (Retained Earnings -606.4m / Total Assets 229.1m)
C: -0.40 (EBIT TTM -84.6m / Avg Total Assets 213.3m)
D: -0.70 (Book Value of Equity -523.7m / Total Liabilities 752.8m)
Altman-Z'' = -7.36 = D
What is the price of ODTX shares?

As of July 08, 2026, the stock is trading at USD 15.91 with a total of 229,207 shares traded. Over the past week, the price has changed by -15.78%, over one month by -7.07%, over three months by -3.11% and over the past year by -3.11%.

Current recommended Stop Loss: 13.80 (which is 13.3% or 1.6 ATR below the current price).

Is ODTX a buy, sell or hold?

Odyssey Therapeutics has no consensus analysts rating.

Odyssey Therapeutics (ODTX) - Fundamental Data Overview as of 05 July 2026
Market Cap USD = 806.9m (806.9m USD * 1.0 USD.USD)
P/S = 762.6901
Revenue TTM = 1.92m USD
EBIT TTM = -84.6m USD
EBITDA TTM = -82.1m USD
Long Term Debt = 20.8m USD (estimated: total debt 26.1m - short term 5.37m)
Short Term Debt = 5.37m USD (from shortTermDebt, last quarter)
Debt = 26.1m USD (from shortLongTermDebtTotal, last quarter) (leases 26.1m already included)
Net Debt = -149.6m USD (calculated: Debt 26.1m - CCE 175.7m)
Enterprise Value = 657.3m USD (806.9m + Debt 26.1m - CCE 175.7m)
Interest Coverage Ratio = -7.05k (Ebit TTM -84.6m / Interest Expense TTM 12.0k)
EV/FCF = -9.43x (Enterprise Value 657.3m / FCF TTM -69.7m)
FCF Yield = -10.61% (FCF TTM -69.7m / Enterprise Value 657.3m)
 FCF Margin = -3.64k% (FCF TTM -69.7m / Revenue TTM 1.92m)
 Net Margin = -4.00k% (Net Income TTM -76.7m / Revenue TTM 1.92m)
 Gross Margin = unknown ((Revenue TTM 1.92m - Cost of Revenue TTM 0.0) / Revenue TTM)
 Tobins Q-Ratio = 2.87 (Enterprise Value 657.3m / Total Assets 229.1m)
Interest Expense / Debt = 0.05% (Interest Expense 12.0k / Debt 26.1m)
Taxrate = 21.0% (US federal default 21%)
NOPAT = -66.8m (EBIT -84.6m * (1 - 21.00%)) [loss with tax shield]
Current Ratio = 6.08 (Total Current Assets 185.1m / Total Current Liabilities 30.4m)
 Debt / Equity = -0.05 (negative equity) (Debt 26.1m / totalStockholderEquity, last quarter -523.7m)
 Debt / EBITDA = 1.82 (negative EBITDA) (Net Debt -149.6m / EBITDA -82.1m)
 Debt / FCF = 2.15 (negative FCF - burning cash) (Net Debt -149.6m / FCF TTM -69.7m)
 Total Stockholder Equity = -488.3m (last fiscal year from totalStockholderEquity)
RoA = -35.97% (Net Income -76.7m / Total Assets 229.1m)
 RoE = 15.71% (negative equity) (Net Income TTM -76.7m / Total Stockholder Equity -488.3m)
 RoCE = 18.09% (negative capital employed) (EBIT -84.6m / Capital Employed (Equity -488.3m + L.T.Debt 20.8m))
 RoIC = -31.50% (negative operating profit) (NOPAT -66.8m / Invested Capital 212.1m)
 WACC = 0.00% (E(806.9m)/V(833.1m) * Re(0.0%) + D(26.1m)/V(833.1m) * Rd(0.05%) * (1-Tc(0.21)))
Discount Rate = 5.29% (= Risk Free + ERP)
Shares (yearly) Correlation: 0.0 | Cagr: 0.0%
 [DCF] Fair Price = unknown (Cash Flow -69.7m)
 Revenue Correlation: 69.89 | Revenue CAGR: 69.41% | SUE: N/A | # QB: 0
EPS current Quarter (2026-06-30): EPS=-0.85 | Chg30d=N/A | Revisions=+0% | Analysts=2
EPS next Quarter (2026-09-30): EPS=-0.89 | Chg30d=N/A | Revisions=+0% | Analysts=2
EPS current Year (2026-12-31): EPS=-4.55 | Chg30d=N/A | Revisions=+0% | GrowthEPS=+0.0% | GrowthRev=+0.0%
EPS next Year (2027-12-31): EPS=-3.88 | Chg30d=N/A | Revisions=+0% | GrowthEPS=+14.7% | GrowthRev=+0.0%
[Analyst] Revisions Ratio: +0% (up=0, down=0)