(ORKA) Oruka Therapeutics - Ratings and Ratios

Exchange: NASDAQ • Country: United States • Currency: USD • Type: Common Stock • ISIN: US6876041087

ORKA: Monoclonal, Antibody, Therapeutics, Psoriasis, Arthritis

Oruka Therapeutics, Inc. (NASDAQ:ORKA) is a clinical-stage biopharmaceutical company specializing in the development of innovative monoclonal antibody therapeutics for psoriasis (PsO) and other inflammatory and immunology (I&I) conditions. The companys pipeline includes multiple candidates targeting key pathways in inflammation. Its lead product, ORKA-001, is a monoclonal antibody targeting the p19 subunit of interleukin-23 (IL-23), a pathway critical in chronic inflammatory diseases, and is currently in Phase 1 clinical trials for PsO. ORKA-002, another monoclonal antibody, targets both interleukin-17A (IL-17A) and interleukin-17F (IL-17F), addressing PsO, psoriatic arthritis, and other I&I conditions. The company also has ORKA-003 in development, targeting an undisclosed pathway, and ORKA-021, a sequential combination regimen of ORKA-002 and ORKA-001, designed to leverage the complementary mechanisms of these two antibodies. Headquartered in Menlo Park, California, Oruka Therapeutics operates in a strategic biotechnology hub, enabling access to cutting-edge research and collaboration opportunities.

Based on and , Oruka Therapeutics, Inc. (NASDAQ:ORKA) is trading at $10.71 with a 20-day average volume of 226,050 shares. The stock is below its 200-day simple moving average (SMA) of $18.66 but above its 50-day SMA of $10.18. The average true range (ATR) of 0.97 indicates moderate volatility. From a perspective, the company has a market capitalization of $888.26 million, reflecting its position as a mid-sized clinical-stage biotech firm. The lack of reported P/E, P/B, and P/S ratios suggests the company is pre-revenue, focusing on advancing its pipeline. Investors should monitor clinical trial progress and regulatory updates, as these will likely drive near-term valuation changes. The stocks technical setup, with support near the 50-day SMA and resistance at the 200-day SMA, may influence short-term trading decisions.

Additional Sources for ORKA Stock

News: Wall Street Journal | Benzinga | Yahoo Finance
Tweets: X | Stocktwits
Fund Manager Positions: Dataroma | Stockcircle

ORKA Stock Overview

Market Cap in USD 888m
Sector Healthcare
Industry Biotechnology
GiC Sub-Industry Biotechnology
IPO / Inception 1997-08-08

ORKA Stock Ratings

Growth Rating -71.0
Fundamental -
Dividend Rating 40.0
Rel. Strength -34.6
Analysts 4.86 of 5
Fair Price Momentum 8.92 USD
Fair Price DCF -

ORKA Dividends

Dividend Yield 12m 121.27%
Yield on Cost 5y 42.06%
Annual Growth 5y -100.00%
Payout Consistency 100.0%
Payout Ratio %

ORKA Growth Ratios

Growth Correlation 3m 31.7%
Growth Correlation 12m -75.1%
Growth Correlation 5y -54.2%
CAGR 5y -22.84%
CAGR/Max DD 5y -0.26
Sharpe Ratio 12m -0.25
Alpha -57.00
Beta 1.574
Volatility 79.15%
Current Volume 131k
Average Volume 20d 137.2k
What is the price of ORKA shares?
As of June 16, 2025, the stock is trading at USD 12.56 with a total of 130,970 shares traded.
Over the past week, the price has changed by +0.16%, over one month by +32.77%, over three months by +5.63% and over the past year by -39.56%.
Is Oruka Therapeutics a good stock to buy?
No, based on ValueRay´s Analyses, Oruka Therapeutics (NASDAQ:ORKA) is currently (June 2025) a stock to sell. It has a ValueRay Growth Rating of -70.97 and therefor a clear technical negative rating according to historical growth.
Based on momentum, paid dividends and discounted-cash-flow analyses, the fair value of ORKA is around 8.92 USD . This means that ORKA is currently overvalued and has a potential downside of -28.98%.
Is ORKA a buy, sell or hold?
Oruka Therapeutics has received a consensus analysts rating of 4.86. Therefor, it is recommend to buy ORKA.
  • Strong Buy: 6
  • Buy: 1
  • Hold: 0
  • Sell: 0
  • Strong Sell: 0
What are the forecasts for ORKA share price target?
According to our own proprietary Forecast Model, ORKA Oruka Therapeutics will be worth about 10.6 in June 2026. The stock is currently trading at 12.56. This means that the stock has a potential downside of -15.84%.
Issuer Target Up/Down from current
Wallstreet Target Price 41.3 228.4%
Analysts Target Price 41.3 228.4%
ValueRay Target Price 10.6 -15.8%