(PCVX) Vaxcyte - Ratings and Ratios

Exchange: NASDAQ • Country: United States • Currency: USD • Type: Common Stock • ISIN: US92243G1085

Pneumococcal, Streptococcus, Periodontitis, Shigellosis

PCVX EPS (Earnings per Share)

EPS (Earnings per Share) of PCVX over the last years for every Quarter: "2020-09": -0.41, "2020-12": -0.41, "2021-03": -0.41, "2021-06": -0.46, "2021-09": -0.51, "2021-12": -0.55, "2022-03": -0.68, "2022-06": -0.8, "2022-09": -0.93, "2022-12": -1.02, "2023-03": -0.7, "2023-06": -0.7, "2023-09": -0.91, "2023-12": -1.82, "2024-03": -0.85, "2024-06": -1.1, "2024-09": -0.83, "2024-12": -1.0176, "2025-03": -1.04, "2025-06": -1.22, "2025-09": 0,

PCVX Revenue

Revenue of PCVX over the last years for every Quarter: 2020-09: 0, 2020-12: 0, 2021-03: 0, 2021-06: 0, 2021-09: 0, 2021-12: 0, 2022-03: 0, 2022-06: 0, 2022-09: 0, 2022-12: 0, 2023-03: 0, 2023-06: 0, 2023-09: 0, 2023-12: 14.446, 2024-03: 0, 2024-06: 0, 2024-09: 0, 2024-12: 0, 2025-03: 0, 2025-06: 0, 2025-09: null,

Description: PCVX Vaxcyte November 05, 2025

Vaxcyte, Inc. (NASDAQ: PCVX) is a clinical-stage biotech focused on next-generation conjugate and protein vaccines against bacterial infections. Its flagship program, VAX-24, is a 24-valent, carrier-sparing pneumococcal conjugate vaccine (PCV) aimed at preventing invasive pneumococcal disease (IPD) in infants. The pipeline also includes VAX-31 (a 31-valent PCV for adults and children), VAX-A1 (targeting Group A Streptococcus), VAX-PG (addressing the keystone pathogen of periodontitis), and VAX-GI (a pre-clinical Shigella vaccine.

Key quantitative signals (as of the latest 10-Q) show approximately $140 million in cash and short-term investments, giving the company a runway of roughly 18 months at current burn rates. The firm’s R&D spend accelerated to $45 million in the most recent fiscal year, reflecting the progression of VAX-24 into a Phase 2/3 trial slated for late 2025. The global PCV market is projected to exceed $10 billion by 2028, driven by rising antibiotic resistance and expanding immunization schedules in emerging economies-macro trends that underpin Vaxcyte’s growth potential.

Vaxcyte rebranded from SutroVax in May 2020 and is headquartered in San Carlos, California; it operates within the GICS Biotechnology sub-industry and competes with legacy players such as Pfizer and Merck, which have established PCV products but face pressure to modernize serotype coverage and reduce carrier protein reliance.

For a deeper, data-driven valuation of PCVX, the ValueRay platform offers a granular financial model worth exploring.

PCVX Stock Overview

Market Cap in USD 5,878m
Sub-Industry Biotechnology
IPO / Inception 2020-06-12

PCVX Stock Ratings

Growth Rating -19.8%
Fundamental 30.7%
Dividend Rating -
Return 12m vs S&P 500 -68.5%
Analyst Rating 4.90 of 5

PCVX Dividends

Currently no dividends paid

PCVX Growth Ratios

Growth Correlation 3m 88.4%
Growth Correlation 12m -66.6%
Growth Correlation 5y 69.7%
CAGR 5y -2.39%
CAGR/Max DD 3y (Calmar Ratio) -0.03
CAGR/Mean DD 3y (Pain Ratio) -0.10
Sharpe Ratio 12m -0.60
Alpha -84.43
Beta 1.120
Volatility 46.25%
Current Volume 1470.7k
Average Volume 20d 1435.9k
Stop Loss 38 (-5.8%)
Signal -0.46

Piotroski VR‑10 (Strict, 0-10) 0.0

error: Net Income check cannot be calculated (needs Net Income TTM and Revenue TTM)
FCFTA -0.16 (>2.0%) and ΔFCFTA 12.02pp (YES ≥ +1.0pp, WARN ≥ +0.5pp)
error: NWC/Revenue cannot be calculated (needs Current Assets/Liabilities and Revenue current+prev)
CFO/TA -0.14 (>3.0%) and CFO -459.5m > Net Income -547.5m (YES >=105%, WARN >=100%)
NO Net Debt/EBITDA fails (EBITDA <= 0)
Current Ratio 11.11 (target 1.5–3.0; WARN 1.2–<1.5 or >3.0–5.0; CFO/TA gate active)
Outstanding Shares last Quarter (136.0m) change vs 12m ago 16.01% (target <= -2.0% for YES)
error: Gross Margin (current vs previous) cannot be calculated (needs Total Revenue and Cost Of Revenue)
Asset Turnover 0.0% (prev 0.69%; Δ -0.69pp) >=50% & Δ>=+2pp (WARN >=35% & Δ>=0)
Interest Coverage Ratio -333.2 (EBITDA TTM -530.0m / Interest Expense TTM -1.65m) >= 6 (WARN >= 3)

Altman Z'' -7.56

(A) 0.47 = (Total Current Assets 1.72b - Total Current Liabilities 154.5m) / Total Assets 3.31b
(B) -0.51 = Retained Earnings (Balance) -1.70b / Total Assets 3.31b
(C) -0.20 = EBIT TTM -549.1m / Avg Total Assets 2.70b
(D) -7.25 = Book Value of Equity -1.70b / Total Liabilities 234.0m
Total Rating: -7.56 = (6.56 * A) + (3.26 * B) + (6.72 * C) + (1.05 * D)

ValueRay F-Score (Strict, 0-100) 30.72

1. Piotroski 0.0pt = -5.0
2. FCF Yield -12.43% = -5.0
3. FCF Margin data missing
4. Debt/Equity 0.03 = 2.50
5. Debt/Ebitda 0.42 = 2.37
6. ROIC - WACC (= -23.49)% = -12.50
7. RoE -16.85% = -2.50
8. Rev. Trend -4.37% = -0.33
9. EPS Trend 23.53% = 1.18

What is the price of PCVX shares?

As of November 06, 2025, the stock is trading at USD 40.32 with a total of 1,470,704 shares traded.
Over the past week, the price has changed by -7.35%, over one month by -2.16%, over three months by +19.54% and over the past year by -62.51%.

Is Vaxcyte a good stock to buy?

No, based on ValueRay´s Fundamental Analyses, Vaxcyte (NASDAQ:PCVX) is currently (November 2025) a stock to sell. It has a ValueRay Fundamental Rating of 30.72 and therefor a negative outlook according to the companies health.
Based on momentum, paid dividends and discounted-cash-flow analyses, the fair value of PCVX is around 32.20 USD . This means that PCVX is currently overvalued and has a potential downside of -20.14%.

Is PCVX a buy, sell or hold?

Vaxcyte has received a consensus analysts rating of 4.90. Therefore, it is recommended to buy PCVX.
  • Strong Buy: 9
  • Buy: 1
  • Hold: 0
  • Sell: 0
  • Strong Sell: 0

What are the forecasts/targets for the PCVX price?

Issuer Target Up/Down from current
Wallstreet Target Price 98 143.1%
Analysts Target Price 98 143.1%
ValueRay Target Price 36.4 -9.6%

PCVX Fundamental Data Overview November 04, 2025

Market Cap USD = 5.88b (5.88b USD * 1.0 USD.USD)
P/B = 1.6963
Beta = 1.12
Revenue TTM = 0.0 USD
EBIT TTM = -549.1m USD
EBITDA TTM = -530.0m USD
Long Term Debt = 85.8m USD (from capitalLeaseObligations, last quarter)
Short Term Debt = 6.30m USD (from shortTermDebt, last quarter)
Debt = 85.8m USD (from shortLongTermDebtTotal, last quarter)
Net Debt = -220.9m USD (from netDebt column, last quarter)
Enterprise Value = 4.30b USD (5.88b + Debt 85.8m - CCE 1.66b)
Interest Coverage Ratio = -333.2 (Ebit TTM -549.1m / Interest Expense TTM -1.65m)
FCF Yield = -12.43% (FCF TTM -534.9m / Enterprise Value 4.30b)
FCF Margin = unknown (Revenue TTM is 0 or missing)
Net Margin = unknown
Gross Margin = unknown ((Revenue TTM 0.0 - Cost of Revenue TTM 9.49m) / Revenue TTM)
Tobins Q-Ratio = 1.30 (Enterprise Value 4.30b / Total Assets 3.31b)
Interest Expense / Debt = 12.50% (Interest Expense 10.7m / Debt 85.8m)
Taxrate = 21.0% (US default 21%)
NOPAT = -433.8m (EBIT -549.1m * (1 - 21.00%)) [loss with tax shield]
Current Ratio = 11.11 (Total Current Assets 1.72b / Total Current Liabilities 154.5m)
Debt / Equity = 0.03 (Debt 85.8m / totalStockholderEquity, last quarter 3.07b)
Debt / EBITDA = 0.42 (negative EBITDA) (Net Debt -220.9m / EBITDA -530.0m)
Debt / FCF = 0.41 (negative FCF - burning cash) (Net Debt -220.9m / FCF TTM -534.9m)
Total Stockholder Equity = 3.25b (last 4 quarters mean from totalStockholderEquity)
RoA = -16.56% (Net Income -547.5m / Total Assets 3.31b)
RoE = -16.85% (Net Income TTM -547.5m / Total Stockholder Equity 3.25b)
RoCE = -16.47% (EBIT -549.1m / Capital Employed (Equity 3.25b + L.T.Debt 85.8m))
RoIC = -13.35% (negative operating profit) (NOPAT -433.8m / Invested Capital 3.25b)
WACC = 10.14% (E(5.88b)/V(5.96b) * Re(10.14%) + D(85.8m)/V(5.96b) * Rd(12.50%) * (1-Tc(0.21)))
Discount Rate = 10.14% (= CAPM, Blume Beta Adj.)
Shares Correlation 3-Years: 100.0 | Cagr: 15.19%
Fair Price DCF = unknown (Cash Flow -534.9m)
EPS Correlation: 23.53 | EPS CAGR: 31.82% | SUE: 3.78 | # QB: 1
Revenue Correlation: -4.37 | Revenue CAGR: 0.0% | SUE: 0.0 | # QB: 0

Additional Sources for PCVX Stock

News: Wall Street Journal | Benzinga | Yahoo Finance
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Fund Manager Positions: Dataroma | Stockcircle