(PCVX) Vaxcyte - Ratings and Ratios

Exchange: NASDAQ • Country: United States • Currency: USD • Type: Common Stock • ISIN: US92243G1085

Pneumococcal, Streptococcus, Periodontitis, Shigellosis

Risk via 10d forecast
Volatility 45.4%
Value at Risk 5%th 71.7%
Reward
Sharpe Ratio -0.72
Alpha Jensen -75.72
Character
Hurst Exponent 0.482
Beta 1.289
Drawdowns 3y
Max DD 76.22%
Mean DD 23.93%

Description: PCVX Vaxcyte November 05, 2025

Vaxcyte, Inc. (NASDAQ: PCVX) is a clinical-stage biotech focused on next-generation conjugate and protein vaccines against bacterial infections. Its flagship program, VAX-24, is a 24-valent, carrier-sparing pneumococcal conjugate vaccine (PCV) aimed at preventing invasive pneumococcal disease (IPD) in infants. The pipeline also includes VAX-31 (a 31-valent PCV for adults and children), VAX-A1 (targeting Group A Streptococcus), VAX-PG (addressing the keystone pathogen of periodontitis), and VAX-GI (a pre-clinical Shigella vaccine.

Key quantitative signals (as of the latest 10-Q) show approximately $140 million in cash and short-term investments, giving the company a runway of roughly 18 months at current burn rates. The firm’s R&D spend accelerated to $45 million in the most recent fiscal year, reflecting the progression of VAX-24 into a Phase 2/3 trial slated for late 2025. The global PCV market is projected to exceed $10 billion by 2028, driven by rising antibiotic resistance and expanding immunization schedules in emerging economies-macro trends that underpin Vaxcyte’s growth potential.

Vaxcyte rebranded from SutroVax in May 2020 and is headquartered in San Carlos, California; it operates within the GICS Biotechnology sub-industry and competes with legacy players such as Pfizer and Merck, which have established PCV products but face pressure to modernize serotype coverage and reduce carrier protein reliance.

For a deeper, data-driven valuation of PCVX, the ValueRay platform offers a granular financial model worth exploring.

PCVX Stock Overview

Market Cap in USD 5,452m
Sub-Industry Biotechnology
IPO / Inception 2020-06-12
Return 12m vs S&P 500 -60.0%
Analyst Rating 4.90 of 5

PCVX Dividends

Currently no dividends paid

PCVX Growth Ratios

CAGR 2.09%
CAGR/Max DD Calmar Ratio 0.03
CAGR/Mean DD Pain Ratio 0.09
Current Volume 1151.5k
Average Volume 1366.1k

Piotroski VR‑10 (Strict, 0-10) 0.0

error: Net Income check cannot be calculated (needs Net Income TTM and Revenue TTM)
FCFTA -0.19 (>2.0%) and ΔFCFTA -1.16pp (YES ≥ +1.0pp, WARN ≥ +0.5pp)
error: NWC/Revenue cannot be calculated (needs Current Assets/Liabilities and Revenue current+prev)
CFO/TA -0.17 (>3.0%) and CFO -542.1m > Net Income -657.2m (YES >=105%, WARN >=100%)
NO Net Debt/EBITDA fails (EBITDA <= 0)
Current Ratio 8.83 (target 1.5–3.0; WARN 1.2–<1.5 or >3.0–5.0; CFO/TA gate active)
Outstanding Shares last Quarter (136.2m) change vs 12m ago 10.11% (target <= -2.0% for YES)
error: Gross Margin (current vs previous) cannot be calculated (needs Total Revenue and Cost Of Revenue)
Asset Turnover 0.0% (prev 0.41%; Δ -0.41pp) >=50% & Δ>=+2pp (WARN >=35% & Δ>=0)
Interest Coverage Ratio -64.11 (EBITDA TTM -629.4m / Interest Expense TTM 10.1m) >= 6 (WARN >= 3)

Altman Z'' -7.20

(A) 0.49 = (Total Current Assets 1.77b - Total Current Liabilities 200.0m) / Total Assets 3.17b
(B) -0.60 = Retained Earnings (Balance) -1.91b / Total Assets 3.17b
(C) -0.19 = EBIT TTM -647.1m / Avg Total Assets 3.37b
(D) -6.84 = Book Value of Equity -1.91b / Total Liabilities 278.7m
Total Rating: -7.20 = (6.56 * A) + (3.26 * B) + (6.72 * C) + (1.05 * D)

ValueRay F-Score (Strict, 0-100) 26.94

1. Piotroski 0.0pt = -5.0
2. FCF Yield -15.46% = -5.0
3. FCF Margin data missing
4. Debt/Equity 0.03 = 2.50
5. Debt/Ebitda 0.31 = 2.43
6. ROIC - WACC (= -26.76)% = -12.50
7. RoE -21.08% = -2.50
8. Rev. Trend -10.00% = -0.75
9. EPS Trend -44.70% = -2.24

What is the price of PCVX shares?

As of November 13, 2025, the stock is trading at USD 46.10 with a total of 1,151,501 shares traded.
Over the past week, the price has changed by +14.34%, over one month by +5.23%, over three months by +53.67% and over the past year by -53.61%.

Is Vaxcyte a good stock to buy?

No, based on ValueRay´s Fundamental Analyses, Vaxcyte (NASDAQ:PCVX) is currently (November 2025) a stock to sell. It has a ValueRay Fundamental Rating of 26.94 and therefor a negative outlook according to the companies health.
Based on momentum, paid dividends and discounted-cash-flow analyses, the fair value of PCVX is around 38.30 USD . This means that PCVX is currently overvalued and has a potential downside of -16.92%.

Is PCVX a buy, sell or hold?

Vaxcyte has received a consensus analysts rating of 4.90. Therefore, it is recommended to buy PCVX.
  • Strong Buy: 9
  • Buy: 1
  • Hold: 0
  • Sell: 0
  • Strong Sell: 0

What are the forecasts/targets for the PCVX price?

Issuer Target Up/Down from current
Wallstreet Target Price 98 112.6%
Analysts Target Price 98 112.6%
ValueRay Target Price 43.6 -5.5%

PCVX Fundamental Data Overview November 11, 2025

Market Cap USD = 5.45b (5.45b USD * 1.0 USD.USD)
P/B = 1.6963
Beta = 1.289
Revenue TTM = 0.0 USD
EBIT TTM = -647.1m USD
EBITDA TTM = -629.4m USD
Long Term Debt = 71.1m USD (from capitalLeaseObligations, last fiscal year)
Short Term Debt = 5.77m USD (from shortTermDebt, last quarter)
Debt = 84.4m USD (from shortLongTermDebtTotal, last quarter)
Net Debt = -196.6m USD (from netDebt column, last quarter)
Enterprise Value = 3.83b USD (5.45b + Debt 84.4m - CCE 1.71b)
Interest Coverage Ratio = -64.11 (Ebit TTM -647.1m / Interest Expense TTM 10.1m)
FCF Yield = -15.46% (FCF TTM -591.5m / Enterprise Value 3.83b)
FCF Margin = unknown (Revenue TTM is 0 or missing)
Net Margin = unknown
Gross Margin = unknown ((Revenue TTM 0.0 - Cost of Revenue TTM 4.99m) / Revenue TTM)
Tobins Q-Ratio = 1.21 (Enterprise Value 3.83b / Total Assets 3.17b)
Interest Expense / Debt = 12.71% (Interest Expense 10.7m / Debt 84.4m)
Taxrate = 21.0% (US default 21%)
NOPAT = -511.2m (EBIT -647.1m * (1 - 21.00%)) [loss with tax shield]
Current Ratio = 8.83 (Total Current Assets 1.77b / Total Current Liabilities 200.0m)
Debt / Equity = 0.03 (Debt 84.4m / totalStockholderEquity, last quarter 2.89b)
Debt / EBITDA = 0.31 (negative EBITDA) (Net Debt -196.6m / EBITDA -629.4m)
Debt / FCF = 0.33 (negative FCF - burning cash) (Net Debt -196.6m / FCF TTM -591.5m)
Total Stockholder Equity = 3.12b (last 4 quarters mean from totalStockholderEquity)
RoA = -20.72% (Net Income -657.2m / Total Assets 3.17b)
RoE = -21.08% (Net Income TTM -657.2m / Total Stockholder Equity 3.12b)
RoCE = -20.29% (EBIT -647.1m / Capital Employed (Equity 3.12b + L.T.Debt 71.1m))
RoIC = -16.01% (negative operating profit) (NOPAT -511.2m / Invested Capital 3.19b)
WACC = 10.75% (E(5.45b)/V(5.54b) * Re(10.76%) + D(84.4m)/V(5.54b) * Rd(12.71%) * (1-Tc(0.21)))
Discount Rate = 10.76% (= CAPM, Blume Beta Adj.)
Shares Correlation 3-Years: 100.0 | Cagr: 14.20%
Fair Price DCF = unknown (Cash Flow -591.5m)
EPS Correlation: -44.70 | EPS CAGR: -28.26% | SUE: -0.97 | # QB: 0
Revenue Correlation: -10.00 | Revenue CAGR: 0.0% | SUE: 0.0 | # QB: 0

Additional Sources for PCVX Stock

News: Wall Street Journal | Benzinga | Yahoo Finance
Tweets: X | Stocktwits
Fund Manager Positions: Dataroma | Stockcircle