(PCVX) Vaxcyte - Overview

Sector: Healthcare | Industry: Biotechnology | Exchange: NASDAQ (USA) | Market Cap: 6.811m USD | Total Return: 39.5% in 12m

Pneumococcal Vaccines, Conjugate Vaccines, Protein Vaccines
Total Rating 21
Safety 30
Buy Signal -1.04
Biotechnology
Industry Rotation: -8.2
Market Cap: 6.81B
Avg Turnover: 73.8M
Risk 3d forecast
Volatility50.3%
VaR 5th Pctl8.56%
VaR vs Median3.44%
Reward TTM
Sharpe Ratio0.86
Rel. Str. IBD48.1
Rel. Str. Peer Group30.8
Character TTM
Beta0.958
Beta Downside0.973
Hurst Exponent0.552
Drawdowns 3y
Max DD76.22%
CAGR/Max DD-0.01
CAGR/Mean DD-0.03
EPS (Earnings per Share) EPS (Earnings per Share) of PCVX over the last years for every Quarter: "2021-03": -0.41, "2021-06": -0.46, "2021-09": -0.51, "2021-12": -0.55, "2022-03": -0.68, "2022-06": -0.8, "2022-09": -0.93, "2022-12": -1.02, "2023-03": -0.7, "2023-06": -0.7, "2023-09": -0.91, "2023-12": -1.82, "2024-03": -0.85, "2024-06": -1.1, "2024-09": -0.83, "2024-12": -1.0176, "2025-03": -1.04, "2025-06": -1.22, "2025-09": -1.56, "2025-12": -1.8, "2026-03": -2.3,
Last SUE: -2.16
Qual. Beats: -3
Revenue Revenue of PCVX over the last years for every Quarter: 2021-03: 0, 2021-06: 0, 2021-09: 0, 2021-12: 0, 2022-03: 0, 2022-06: 0, 2022-09: 0, 2022-12: 0, 2023-03: 0, 2023-06: 0, 2023-09: 0, 2023-12: 14.446, 2024-03: 0, 2024-06: 0, 2024-09: 0, 2024-12: 0, 2025-03: 0, 2025-06: 0, 2025-09: 0, 2025-12: 0, 2026-03: 0,
Last SUE: 0.00
Qual. Beats: 0

Warnings

Altman Z'' -8.67 < 1.0 - financial distress zone

Below Avwap Earnings

Tailwinds

No distinct edge detected

Description: PCVX Vaxcyte

Vaxcyte, Inc. is a clinical-stage biotechnology firm specializing in the development of conjugate and protein vaccines targeting bacterial infections. Its primary focus is the pneumococcal conjugate vaccine (PCV) market, led by candidates VAX-24 and VAX-31, which aim to prevent invasive pneumococcal disease across pediatric and adult populations. The company utilizes a proprietary cell-free protein synthesis platform designed to overcome the carrier suppression limitations often found in traditional vaccine manufacturing.

The vaccine sector is characterized by high barriers to entry and long development cycles, often requiring extensive clinical trials to meet stringent safety and efficacy standards for public health use. Vaxcyte’s pipeline extends beyond respiratory pathogens to include candidates for Group A Streptococcus, periodontitis, and Shigella. Examining the historical performance of similar clinical-stage biotechs on ValueRay can provide useful context for evaluating its current trajectory.

Headquartered in San Carlos, California, the company transitioned from its original name, SutroVax, in 2020. Its business model relies on advancing its investigational candidates through the regulatory pipeline to address unmet needs in the global infectious disease landscape.

Headlines to Watch Out For
  • Clinical trial data for VAX-31 and VAX-24 determines competitive positioning against Pfizer
  • Regulatory approval timelines for infant pneumococcal vaccines dictate long-term market entry
  • Manufacturing scalability and production costs impact future gross margins for conjugate vaccines
  • Market share competition with established incumbents Pfizer and Merck drives valuation
  • Capital expenditure requirements for late-stage clinical trials influence future equity financing needs
Piotroski VR‑10 (Strict) 0.0
Net Income: error (cannot be calculated; needs Net Income TTM and Revenue TTM)
FCF/TA: -0.23 > 0.02 and ΔFCF/TA -5.29 > 1.0
NWC/Revenue: error (cannot be calculated; needs Current Assets/Liabilities and Revenue current+prev)
CFO/TA -0.23 > 3% & CFO -769.9m > Net Income -946.5m
Net Debt/EBITDA: error (EBITDA <= 0)
Current Ratio: 7.49 > 1.5 & < 3
Outstanding Shares: last quarter (139.5m) vs 12m ago 2.81% < -2%
Gross Margin: error (current vs previous; cannot be calculated due to missing/invalid data or negative margin)
Asset Turnover: 0.0% > 50% (prev 0.0%; Δ 0.0% > 0%)
Interest Coverage Ratio: error (cannot be calculated; needs correct EBITDA TTM and Interest Expense TTM)
Altman Z'' -8.67
A: 0.47 (Total Current Assets 1.81b - Total Current Liabilities 242.1m) / Total Assets 3.35b
B: -0.74 (Retained Earnings -2.48b / Total Assets 3.35b)
C: -0.29 (EBIT TTM -971.8m / Avg Total Assets 3.36b)
D: -7.05 (Book Value of Equity -2.48b / Total Liabilities 352.3m)
Altman-Z'' = -8.67 = D
What is the price of PCVX shares? As of May 22, 2026, the stock is trading at USD 47.39 with a total of 1,112,761 shares traded.
Over the past week, the price has changed by -11.47%, over one month by -21.73%, over three months by -21.36% and over the past year by +39.51%.
Is PCVX a buy, sell or hold? Vaxcyte has received a consensus analysts rating of 4.90. Therefore, it is recommended to buy PCVX.
  • StrongBuy: 9
  • Buy: 1
  • Hold: 0
  • Sell: 0
  • StrongSell: 0
What are the forecasts/targets for the PCVX price?
Analysts Target Price 109 130%
Vaxcyte (PCVX) - Fundamental Data Overview as of 22 May 2026
P/B = 2.2734
Revenue TTM = 0.0 USD
EBIT TTM = -971.8m USD
EBITDA TTM = -945.9m USD
Long Term Debt = 110.2m USD (estimated: total debt 116.3m - short term 6.08m)
Short Term Debt = 6.08m USD (from shortTermDebt, last quarter)
Debt = 116.3m USD (from shortLongTermDebtTotal, last quarter) (leases 116.3m already included)
Net Debt = -1.62b USD (calculated: Debt 116.3m - CCE 1.74b)
Enterprise Value = 5.19b USD (6.81b + Debt 116.3m - CCE 1.74b)
 Interest Coverage Ratio = unknown (Ebit TTM -971.8m / Interest Expense TTM 0.0)
 EV/FCF = -6.73x (Enterprise Value 5.19b / FCF TTM -771.7m)
FCF Yield = -14.87% (FCF TTM -771.7m / Enterprise Value 5.19b)
 FCF Margin = unknown (Revenue TTM is 0 or missing)
 Net Margin = unknown
 Gross Margin = unknown ((Revenue TTM 0.0 - Cost of Revenue TTM 5.85m) / Revenue TTM)
 Tobins Q-Ratio = 1.55 (Enterprise Value 5.19b / Total Assets 3.35b)
Interest Expense / Debt = 0.0% (Interest Expense 0.0 / Debt 116.3m)
Taxrate = 21.0% (US default 21%)
NOPAT = -767.7m (EBIT -971.8m * (1 - 21.00%)) [loss with tax shield]
Current Ratio = 7.49 (Total Current Assets 1.81b / Total Current Liabilities 242.1m)
Debt / Equity = 0.04 (Debt 116.3m / totalStockholderEquity, last quarter 3.00b)
 Debt / EBITDA = 1.71 (negative EBITDA) (Net Debt -1.62b / EBITDA -945.9m)
 Debt / FCF = 2.10 (negative FCF - burning cash) (Net Debt -1.62b / FCF TTM -771.7m)
 Total Stockholder Equity = 2.91b (last 4 quarters mean from totalStockholderEquity)
RoA = -28.14% (Net Income -946.5m / Total Assets 3.35b)
RoE = -17.57% (Net Income TTM -946.5m / Total Stockholder Equity 5.39b)
RoCE = -17.68% (EBIT -971.8m / Capital Employed (Equity 5.39b + L.T.Debt 110.2m))
 RoIC = -55.83% (negative operating profit) (NOPAT -767.7m / Invested Capital 1.38b)
 WACC = 9.19% (E(6.81b)/V(6.93b) * Re(9.35%) + D(116.3m)/V(6.93b) * Rd(0.0%) * (1-Tc(0.21)))
Discount Rate = 9.35% (= CAPM, Blume Beta Adj.)
Shares (quarterly) Correlation: 91.11 | Cagr: 13.74%
 [DCF] Fair Price = unknown (Cash Flow -771.7m)
 EPS Correlation: N/A | EPS CAGR: N/A | SUE: -2.16 | # QB: -3
Revenue Correlation: N/A | Revenue CAGR: N/A | SUE: 0.0 | # QB: 0
EPS current Quarter (2026-06-30): EPS=-2.10 | Chg30d=-13.48% | Revisions=-50% | Analysts=7
EPS next Quarter (2026-09-30): EPS=-2.16 | Chg30d=-9.86% | Revisions=-50% | Analysts=7
EPS current Year (2026-12-31): EPS=-8.48 | Chg30d=-14.79% | Revisions=-56% | GrowthEPS=-50.7% | GrowthRev=+0.0%
EPS next Year (2027-12-31): EPS=-7.42 | Chg30d=-1.83% | Revisions=-33% | GrowthEPS=+12.5% | GrowthRev=+0.0%
[Analyst] Revisions Ratio: -56%