(PCVX) Vaxcyte - Ratings and Ratios

Exchange: NASDAQ • Country: United States • Currency: USD • Type: Common Stock • ISIN: US92243G1085

PCVX: Pneumococcal, Streptococcal, Periodontitis, Gastrointestinal, Vaccines

Vaxcyte, Inc. (NASDAQ:PCVX) is a clinical-stage biotechnology company specializing in the development of conjugate and novel protein vaccines to address unmet needs in bacterial infectious diseases. The companys lead candidate, VAX-24, is a 24-valent, carrier-sparing pneumococcal conjugate vaccine (PCV) designed to prevent invasive pneumococcal disease (IPD). This vaccine candidate is notable for its broader serotype coverage compared to existing PCVs, potentially offering enhanced protection against pneumococcal infections. VAX-24 is currently in Phase 2 clinical trials, with a focus on demonstrating its immunogenicity and safety.

Complementing VAX-24, Vaxcyte is advancing VAX-31, a 31-valent PCV, which is in preclinical development. This candidate aims to further expand serotype coverage, addressing a broader range of pneumococcal strains. The company also has VAX-A1, a conjugate vaccine targeting Group A Streptococcus (GAS), a major cause of infectious diseases worldwide. Additionally, Vaxcyte is developing VAX-PG, a novel protein vaccine for periodontitis, and VAX-GI, aimed at preventing shigellosis and dysentery caused by Shigella and enterotoxigenic Escherichia coli (ETEC).

Originally founded in 2013 as SutroVax, Inc., the company rebranded as Vaxcyte, Inc. in May 2020 to reflect its expanded focus on vaccine development. Headquartered in San Carlos, California, Vaxcyte operates in the biotechnology sector with a market capitalization of approximately $3.89 billion USD as of the latest data. The companys stock is listed on the NASDAQ exchange under the ticker symbol PCVX.

From a technical perspective, Vaxcytes stock has shown recent price fluctuations, with a last price of $32.92 and a 20-day average volume of 2,710,706 shares. The stocks short-term moving averages (SMA 20: $33.62, SMA 50: $58.74) indicate a recent downtrend, while the long-term SMA 200 ($85.09) reflects a steeper decline over the past year. The Average True Range (ATR) of $4.23 suggests moderate volatility in recent trading sessions.

On the fundamental side, Vaxcytes price-to-book (P/B) ratio of 1.25 indicates that the stock is trading near its book value. However, the return on equity (RoE) of -14.03% highlights the companys current operating losses, typical for a clinical-stage biotech firm. With no P/E or P/S ratios available due to the absence of earnings or sales, investors are likely focusing on the companys pipeline progress and long-term growth potential.

Based on and , Vaxcytes stock (PCVX) is expected to remain volatile over the next three months. The 20-day average volume of 2.71 million shares suggests moderate liquidity, while the ATR of $4.23 indicates potential price swings. The decline in SMA 20 and SMA 50 relative to SMA 200 suggests bearish momentum, which may persist unless positive catalysts emerge. From a perspective, Vaxcytes market cap of $3.89 billion USD and P/B ratio of 1.25 suggest that investors are pricing in the companys pipeline potential. The negative RoE of -14.03% reflects ongoing R&D investments without revenue generation. In the next three months, key catalysts for PCVX may include updates on VAX-24s Phase 2 trial results, progress with VAX-31s preclinical development, or partnerships/licensing agreements. Positive developments in any of these areas could drive upward momentum, while delays or setbacks may exacerbate the stocks recent downtrend.

Additional Sources for PCVX Stock

PCVX Stock Overview

Market Cap in USD 4,565m
Sector Healthcare
Industry Biotechnology
GiC Sub-Industry Biotechnology
IPO / Inception 2020-06-12

PCVX Stock Ratings

Growth Rating 25.4
Fundamental -
Dividend Rating 0.0
Rel. Strength -46.3
Analysts 4.9/5
Fair Price Momentum 23.38 USD
Fair Price DCF -

PCVX Dividends

No Dividends Paid

PCVX Growth Ratios

Growth Correlation 3m -86.2%
Growth Correlation 12m -13.8%
Growth Correlation 5y 73.2%
CAGR 5y 3.83%
CAGR/Max DD 5y 0.05
Sharpe Ratio 12m -0.06
Alpha -69.41
Beta 1.908
Volatility 96.49%
Current Volume 3169.9k
Average Volume 20d 1953.3k
What is the price of PCVX stocks?
As of May 09, 2025, the stock is trading at USD 31.45 with a total of 3,169,856 shares traded.
Over the past week, the price has changed by -10.75%, over one month by +4.14%, over three months by -63.40% and over the past year by -52.91%.
Is Vaxcyte a good stock to buy?
Neither. Based on ValueRay Analyses, Vaxcyte is currently (May 2025) neither a good nor a bad stock to buy. It has a ValueRay Growth Rating of 25.36 and therefor a technical neutral rating according to historical growth.
Based on ValueRays Analyses, Dividends and Discounted-Cash-Flow, the Fair Value of PCVX as of May 2025 is 23.38. This means that PCVX is currently overvalued and has a potential downside of -25.66%.
Is PCVX a buy, sell or hold?
Vaxcyte has received a consensus analysts rating of 4.90. Therefor, it is recommend to buy PCVX.
  • Strong Buy: 9
  • Buy: 1
  • Hold: 0
  • Sell: 0
  • Strong Sell: 0
What are the forecast for PCVX stock price target?
According to ValueRays Forecast Model, PCVX Vaxcyte will be worth about 27.9 in May 2026. The stock is currently trading at 31.45. This means that the stock has a potential downside of -11.22%.
Issuer Forecast Upside
Wallstreet Target Price 132 319.7%
Analysts Target Price 132 319.7%
ValueRay Target Price 27.9 -11.2%