PRAX Stock Analysis: Praxis Precision Medicines | NASDAQ

Biotechnology | NASDAQ, USA | Market Cap: 7.063m USD | 12M Return: 43.9% | US74006W2070 | Charts, Fundamentals & Technical Analysis

Ulixacaltamide, Relutrigine, Vormatrigine, Elsunersen
Total Rating 31
Safety 57
Buy Signal -0.70
Biotechnology
Industry Rotation: -0.3
Market Cap: 7.06B
Avg Turnover: 137M
Risk 3d forecast
Volatility79.3%
VaR 5th Pctl12.3%
VaR vs Median-5.51%
Reward TTM
Sharpe Ratio0.80
Rel. Str. IBD28
Rel. Str. Peer Group31.3 pctl
Character TTM
Beta2.058
Beta Downside2.516
Hurst Exponent0.532
Choppyness46.6%
Drawdowns 3y
Max DD68.64%
CAGR/Max DD2.35
CAGR/Mean DD8.10
EPS (Earnings per Share) EPS (Earnings per Share) of PRAX over the last years for every Quarter: "2021-09": -15, "2021-12": -19.5, "2022-03": -1.51, "2022-06": -19.8, "2022-09": -14.4, "2022-12": -13.05, "2023-03": -10.65, "2023-06": -7.35, "2023-09": -2.7, "2023-12": -2.97, "2024-03": -2.84, "2024-06": -1.74, "2024-09": -2.75, "2024-12": -2.94, "2025-03": -3.29, "2025-06": -3.31, "2025-09": -3.36, "2025-12": -3.5, "2026-03": -3.2, "2026-06": -2.87,
Last SUE: 1.65
Qual. Beats: 2
Revenue Revenue of PRAX over the last years for every Quarter: 2021-09: 0, 2021-12: 0, 2022-03: 0, 2022-06: 0, 2022-09: 0, 2022-12: 0, 2023-03: 0.683, 2023-06: 0.781, 2023-09: 0.468, 2023-12: 0.515, 2024-03: 0.431, 2024-06: 0.357, 2024-09: 0.302, 2024-12: 7.463, 2025-03: 0, 2025-06: 0, 2025-09: 0, 2025-12: 0, 2026-03: 0, 2026-06: 0,
Last SUE: 0.00
Qual. Beats: 0

Warnings

Strong Share Dilution
Below Avwap Earnings
Below Sma 200d

Tailwinds

No distinct edge detected

Seasonality 5.9 years of data

Jan +2.0% 9
Feb -8.4% 29
Mar -10.5% 11
Apr -7.4% 11
May +1.5% 10
Jun -10.5% 11
Jul +19.2% 11
Aug +0.1% 9
Sep +0.5% 9
Oct +7.7% 27
Nov +2.9% 10
Dec +23.1% 31

How good or bad each month usually is (without trend). The score below shows how much you can trust it: 0 = pure chance, >40 gets interesting and >55 is strong.

Description: PRAX Praxis Precision Medicines

Praxis Precision Medicines (PRAX) is a U.S.-based, clinical-stage biopharmaceutical company headquartered in Boston, Massachusetts, focused on developing precision therapies for central nervous system (CNS) disorders driven by neuronal excitation-inhibition imbalance. The company operates two technology platforms-Cerebrum for orally bioavailable small molecules and Solidus for antisense oligonucleotide (ASO) discovery-and is advancing a pipeline led by ulixacaltamide (NDA-stage for essential tremor), relutrigine (NDA-stage for SCN2A/SCN8A DEEs; Phase 3 for broad DEEs), vormatrigine (Phase 3 focal epilepsy), and Elsunersen (Phase 3 SCN2A-DEE), alongside earlier preclinical candidates including PRAX-020, PRAX-080, PRAX-090, and PRAX-100.

As is typical for clinical-stage biopharmas, Praxis relies on capital markets and partnership milestones rather than product revenue, supporting discovery, clinical development, and NDA-enabling activities. The company maintains external collaborations with RogCon, Ionis Pharmaceuticals, and an unnamed iontophoretic transdermal patch developer for ulixacaltamide delivery. The GICS sub-industry classification is Biotechnology, and the stock trades on NASDAQ as a mid-cap (~$8.25B USD market cap), having gone public in October 2020.

Headlines to Watch Out For
  • Ulixacaltamide NDA decision for essential tremor approaches
  • Phase 3 relutrigine DEE and vormatrigine epilepsy data readouts
  • Cash runway and capital raises fund late-stage CNS pipeline
Piotroski VR-10 (Strict) 0.0
Net Income: error (cannot be calculated; needs Net Income TTM and Revenue TTM)
FCF/TA: -0.22 > 0.02 and ΔFCF/TA 20.19 > 1.0
NWC/Revenue: error (cannot be calculated; needs Current Assets/Liabilities and Revenue current+prev)
CFO/TA -0.22 > 3% & CFO -305.7m > Net Income -339.1m
Net Debt/EBITDA: error (EBITDA <= 0)
Current Ratio: 15.73 > 1.5 & < 3
Outstanding Shares: last quarter (29.1m) vs 12m ago 35.65% < -2%
Gross Margin: error (current vs previous; cannot be calculated due to missing/invalid data or negative margin)
Asset Turnover: 0.0% > 50% (prev 1.71%; Δ -1.71% > 0%)
Interest Coverage Ratio: error (cannot be calculated; needs correct EBIT TTM and Interest Expense TTM)
Altman Z'' 10.00
A: 0.52 (Total Current Assets 771.9m - Total Current Liabilities 49.1m) / Total Assets 1.39b
B: -0.95 (Retained Earnings -1.32b / Total Assets 1.39b)
C: -0.37 (EBIT TTM -339.1m / Avg Total Assets 921.5m)
D: 27.34 (Book Value of Equity 1.34b / Total Liabilities 49.1m)
Altman-Z'' = 26.55 = AAA
What is the price of PRAX shares?

As of October 28, 2026, the stock is trading at USD 267.59 with a total of 382,295 shares traded. Over the past week, the price has changed by +1.17%, over one month by -6.32%, over three months by -15.27% and over the past year by +43.91%.

Current recommended Stop Loss: 251.30 (which is 6.1% or 1.2 ATR below the current price).

Is PRAX a buy, sell or hold?

Praxis Precision Medicines has received a consensus analysts rating of 4.52. Therefore, it is recommended to buy PRAX.

  • StrongBuy: 15
  • Buy: 4
  • Hold: 1
  • Sell: 0
  • StrongSell: 1

What are the forecasts/targets for the PRAX price?
Analysts Target Price 650 142.9%
Praxis Precision Medicines (PRAX) - Fundamental Data Overview as of 27 October 2026
Market Cap USD = 7.06b (7.06b USD * 1.0 USD.USD)
P/S = 144.694
P/B = 6.8867
Revenue TTM = 0.0 USD
EBIT TTM = -339.1m USD
EBITDA TTM = -339.0m USD
 Long Term Debt = unknown (0.0)
 Short Term Debt = 1.09m USD (from shortTermDebt, last quarter)
Debt = 1.09m USD (from shortLongTermDebtTotal, last quarter) (leases 1.09m already included)
Net Debt = -757.5m USD (calculated: Debt 1.09m - CCE 758.6m)
Enterprise Value = 6.31b USD (7.06b + Debt 1.09m - CCE 758.6m)
 Interest Coverage Ratio = unknown (Ebit TTM -339.1m / Interest Expense TTM 0.0)
 EV/FCF = -20.61x (Enterprise Value 6.31b / FCF TTM -306.0m)
FCF Yield = -4.85% (FCF TTM -306.0m / Enterprise Value 6.31b)
 FCF Margin = unknown (Revenue TTM is 0 or missing)
 Net Margin = unknown
 Gross Margin = unknown ((Revenue TTM 0.0 - Cost of Revenue TTM 140k) / Revenue TTM)
 Tobins Q-Ratio = 4.54 (Enterprise Value 6.31b / Total Assets 1.39b)
Interest Expense / Debt = 0.0% (Interest Expense 0.0 / Debt 1.09m)
Taxrate = 21.0% (US federal default 21%)
NOPAT = -267.9m (EBIT -339.1m * (1 - 21.00%)) [loss with tax shield]
Current Ratio = 15.73 (Total Current Assets 771.9m / Total Current Liabilities 49.1m)
Debt / Equity = 0.00 (Debt 1.09m / totalStockholderEquity, last quarter 1.34b)
 Debt / EBITDA = 2.23 (negative EBITDA) (Net Debt -757.5m / EBITDA -339.0m)
 Debt / FCF = 2.48 (negative FCF - burning cash) (Net Debt -757.5m / FCF TTM -306.0m)
 Total Stockholder Equity = 993.2m (last 4 quarters mean from totalStockholderEquity)
RoA = -36.80% (Net Income -339.1m / Total Assets 1.39b)
RoE = -34.15% (Net Income TTM -339.1m / Total Stockholder Equity 993.2m)
RoCE = -34.15% (EBIT -339.1m / Capital Employed (Equity 993.2m + L.T.Debt 0.0))
 RoIC = -19.96% (negative operating profit) (NOPAT -267.9m / Invested Capital 1.34b)
 WACC = 12.54% (E(7.06b)/V(7.06b) * Re(12.54%) + D(1.09m)/V(7.06b) * Rd(0.0%) * (1-Tc(0.21)))
Discount Rate = 12.54% (= CAPM, Blume Beta Adj.)
Shares (quarterly) Correlation: 93.15 | Cagr: 38.92%
 [DCF] Fair Price = unknown (Cash Flow -306.0m)
 EPS Correlation: N/A | EPS CAGR: N/A | SUE: 1.65 | # QB: 2
Revenue Correlation: N/A | Revenue CAGR: N/A | SUE: 0.0 | # QB: 0
EPS current Quarter (2026-09-30): EPS=-3.63 | Chg30d=-0.08% | Revisions=+42% | Analysts=19
EPS current Year (2026-12-31): EPS=-14.02 | Chg30d=-0.64% | Revisions=+74% | GrowthEPS=-4.0% | GrowthRev=+0.0%
EPS next Year (2027-12-31): EPS=-9.50 | Chg30d=-2.24% | Revisions=+0% | GrowthEPS=+32.2% | GrowthRev=+41442.6%
[Analyst] Revisions Ratio: +59% (up=28, down=6)