(PRTA) Prothena - Ratings and Ratios

Exchange: NASDAQ • Country: Ireland • Currency: USD • Type: Common Stock • ISIN: IE00B91XRN20

Birtamimab, Prasinezumab, Amyloidosis, Parkinsons, Alzheimers

PRTA EPS (Earnings per Share)

EPS (Earnings per Share) of PRTA over the last years for every Quarter: "2020-03": -0.59, "2020-06": -0.66, "2020-09": -0.77, "2020-12": -0.77, "2021-03": -0.91, "2021-06": 0.58, "2021-09": 2.13, "2021-12": -0.71, "2022-03": -0.78, "2022-06": -0.88, "2022-09": -0.97, "2022-12": 0.12, "2023-03": -0.89, "2023-06": -1.03, "2023-09": 0.38, "2023-12": -1.26, "2024-03": -1.34, "2024-06": 1.22, "2024-09": -1.1, "2024-12": -1.08, "2025-03": -1.12,

PRTA Revenue

Revenue of PRTA over the last years for every Quarter: 2020-03: 0.141, 2020-06: 0.195, 2020-09: 0.157, 2020-12: 0.36, 2021-03: 0.16, 2021-06: 60.071, 2021-09: 139.174, 2021-12: 1.172, 2022-03: 1.153, 2022-06: 1.312, 2022-09: 1.517, 2022-12: 49.923, 2023-03: 2.169, 2023-06: 4.019, 2023-09: 84.866, 2023-12: 0.316, 2024-03: 0.05, 2024-06: 132.014, 2024-09: 0.97, 2024-12: 2.123, 2025-03: 2.828,

Description: PRTA Prothena

Prothena Corporation plc is a late-stage clinical biotechnology company that focuses on developing novel therapies for diseases caused by protein dysregulation. The companys product pipeline is diverse, with multiple investigational antibodies and vaccines targeting various neurodegenerative diseases, including AL amyloidosis, Parkinsons disease, Alzheimers disease, and transthyretin amyloidosis.

The companys lead product, birtamimab, is in Phase 3 clinical trials for AL amyloidosis, while Prasinezumab, a humanized monoclonal antibody, is in Phase 2b clinical trials for Parkinsons disease and other synucleinopathies. Additionally, Prothena is developing Coramitug, BMS-986446, PRX012, PRX123, and PRX019, which are in various stages of clinical trials for different neurodegenerative diseases.

Prothena has established strategic partnerships with major pharmaceutical companies, including F. Hoffmann-La Roche Ltd. and Bristol Myers Squibb, to develop and commercialize its antibodies. These collaborations not only provide financial support but also leverage the expertise of these companies to accelerate the development of Prothenas product pipeline.

Analyzing the technical data, the stocks current price is $7.43, significantly lower than its 52-week high of $24.79. The short-term and long-term moving averages (SMA20: $8.95, SMA50: $11.40, SMA200: $15.73) indicate a downtrend, suggesting that the stock has been under selling pressure. However, the Average True Range (ATR) of 0.77, representing a 10.40% volatility, indicates that the stock is experiencing significant price fluctuations.

From a fundamental perspective, Prothenas market capitalization is approximately $469.37 million, with a forward P/E ratio of 64.10, indicating that investors are willing to pay a premium for the companys growth potential. The negative Return on Equity (RoE) of -23.24% is expected, given the companys focus on R&D and lack of commercialized products.

Based on the technical and fundamental data, a forecast for Prothena Corporation plc can be made. The stocks current price is near its 52-week low, and the ATR indicates significant volatility. If the companys ongoing clinical trials yield positive results, particularly for birtamimab and Prasinezumab, the stock price could experience a significant upward movement. Conversely, if the trials fail or the company faces regulatory hurdles, the stock price could decline further. Therefore, a potential price target for PRTA could be in the range of $12-$18, representing a 60%-140% increase from the current price, assuming positive clinical trial results and successful commercialization of its product pipeline.

Additional Sources for PRTA Stock

News: Wall Street Journal | Benzinga | Yahoo Finance
Tweets: X | Stocktwits
Fund Manager Positions: Dataroma | Stockcircle

PRTA Stock Overview

Market Cap in USD 333m
Sector Healthcare
Industry Biotechnology
GiC Sub-Industry Biotechnology
IPO / Inception 2012-12-21

PRTA Stock Ratings

Growth Rating -43.1
Fundamental -
Dividend Rating 0.0
Rel. Strength -65.1
Analysts 4.3 of 5
Fair Price Momentum 4.62 USD
Fair Price DCF -

PRTA Dividends

Currently no dividends paid

PRTA Growth Ratios

Growth Correlation 3m -83.2%
Growth Correlation 12m -94.5%
Growth Correlation 5y -13.6%
CAGR 5y -9.63%
CAGR/Max DD 5y -0.10
Sharpe Ratio 12m 0.06
Alpha -85.63
Beta 1.272
Volatility 63.83%
Current Volume 636.8k
Average Volume 20d 1502.5k
What is the price of PRTA shares?
As of July 07, 2025, the stock is trading at USD 6.44 with a total of 636,811 shares traded.
Over the past week, the price has changed by +6.01%, over one month by +18.95%, over three months by -40.64% and over the past year by -68.11%.
Is Prothena a good stock to buy?
Probably not. Based on ValueRay´s Analyses, Prothena (NASDAQ:PRTA) is currently (July 2025) not a good stock to buy. It has a ValueRay Growth Rating of -43.06 and therefor a somwhat technical negative rating according to historical growth.
Based on momentum, paid dividends and discounted-cash-flow analyses, the fair value of PRTA is around 4.62 USD . This means that PRTA is currently overvalued and has a potential downside of -28.26%.
Is PRTA a buy, sell or hold?
Prothena has received a consensus analysts rating of 4.30. Therefore, it is recommended to buy PRTA.
  • Strong Buy: 5
  • Buy: 3
  • Hold: 2
  • Sell: 0
  • Strong Sell: 0
What are the forecasts for PRTA share price target?
According to our own proprietary Forecast Model, PRTA Prothena will be worth about 5.5 in July 2026. The stock is currently trading at 6.44. This means that the stock has a potential downside of -13.98%.
Issuer Target Up/Down from current
Wallstreet Target Price 24.3 277.2%
Analysts Target Price 49 660.9%
ValueRay Target Price 5.5 -14%