(PTGX) Protagonist Therapeutics - Ratings and Ratios

Exchange: NASDAQ • Country: United States • Currency: USD • Type: Common Stock • ISIN: US74366E1029

Peptide Therapeutics, Injectable Hepcidin Mimetic, Oral Integrin Antagonist

PTGX EPS (Earnings per Share)

EPS (Earnings per Share) of PTGX over the last years for every Quarter: "2020-03": -0.72, "2020-06": -0.59, "2020-09": -0.21, "2020-12": -0.48, "2021-03": -0.54, "2021-06": -0.69, "2021-09": -0.7, "2021-12": -0.77, "2022-03": -0.43, "2022-06": -0.83, "2022-09": -0.61, "2022-12": -0.64, "2023-03": -0.62, "2023-06": -0.68, "2023-09": -0.58, "2023-12": 0.44, "2024-03": 3.26, "2024-06": -0.5, "2024-09": -0.54, "2024-12": 1.98, "2025-03": -0.19,

PTGX Revenue

Revenue of PTGX over the last years for every Quarter: 2020-03: 3.647, 2020-06: 6.217, 2020-09: 13.114, 2020-12: 5.65, 2021-03: 6.189, 2021-06: 2.265, 2021-09: 10.286, 2021-12: 8.617, 2022-03: 25.722, 2022-06: 0.859, 2022-09: 0, 2022-12: 0, 2023-03: 0, 2023-06: 0, 2023-09: 0, 2023-12: 60, 2024-03: 254.953, 2024-06: 4.167, 2024-09: 4.675, 2024-12: 170.638, 2025-03: 28.321,

Description: PTGX Protagonist Therapeutics

Protagonist Therapeutics, Inc. is a biopharmaceutical company that specializes in developing innovative peptide therapeutics for treating hematology and blood disorders, as well as inflammatory and immunomodulatory diseases. With a robust pipeline, the company is advancing multiple promising candidates, including Rusfertide, a hepcidin mimetic in Phase 3 trials for polycythemia vera, and Icotrokinra, an orally delivered investigational drug in Phase 3 trials targeting pathways currently addressed by injectable antibody drugs.

The companys diverse portfolio also includes PN-943, an orally delivered, gut-restricted alpha4 beta7 specific integrin antagonist that has completed Phase 2 trials in patients with moderate to severe ulcerative colitis, demonstrating its potential in treating inflammatory bowel diseases. Additionally, Protagonist Therapeutics is developing IL-17 oral peptide antagonist PN-88, an oral metabolic/obesity peptide program, and an oral hepcidin mimetic/ferroportin blocker, currently in pre-clinical stages, showcasing its commitment to exploring novel therapeutic approaches.

From a technical analysis perspective, PTGX has shown a strong upward trend, with its last price of $56.32 exceeding its SMA20, SMA50, and SMA200, indicating a positive momentum. The Average True Range (ATR) of 1.88, equivalent to 3.34%, suggests moderate volatility. Given the current technical setup, a potential forecast could be that PTGX continues its upward trajectory, potentially reaching towards its 52-week high of $59.76, driven by positive developments in its clinical trials and the overall growth in the biotech sector.

Fundamentally, Protagonist Therapeutics has a market capitalization of $2.94 billion, with a P/E ratio of 60.86 and a forward P/E of 26.39, indicating high growth expectations. The companys Return on Equity (RoE) stands at 9.22%, suggesting a decent return for shareholders. Combining fundamental and technical insights, a forecast for PTGX could be that it maintains its growth trajectory, driven by successful clinical trial outcomes and strategic development of its pipeline, potentially leading to a revaluation of its stock price in line with its growth prospects.

Looking ahead, if Protagonist Therapeutics successfully advances its pipeline, particularly with Rusfertide and Icotrokinra in Phase 3 trials, and achieves positive results, this could significantly enhance its valuation. A potential target could be a 15-20% increase in stock price over the next quarter, driven by positive clinical updates and continued investor confidence in the companys innovative approach to treating significant unmet medical needs.

Additional Sources for PTGX Stock

News: Wall Street Journal | Benzinga | Yahoo Finance
Tweets: X | Stocktwits
Fund Manager Positions: Dataroma | Stockcircle

PTGX Stock Overview

Market Cap in USD 3,426m
Sector Healthcare
Industry Biotechnology
GiC Sub-Industry Biotechnology
IPO / Inception 2016-08-11

PTGX Stock Ratings

Growth Rating 51.3
Fundamental -
Dividend Rating 0.0
Rel. Strength 57.9
Analysts 4.4 of 5
Fair Price Momentum 49.94 USD
Fair Price DCF 81.64 USD

PTGX Dividends

Currently no dividends paid

PTGX Growth Ratios

Growth Correlation 3m 74.2%
Growth Correlation 12m 47%
Growth Correlation 5y 36.5%
CAGR 5y 22.93%
CAGR/Max DD 5y 0.27
Sharpe Ratio 12m 0.20
Alpha 36.63
Beta 0.559
Volatility 61.71%
Current Volume 1219.4k
Average Volume 20d 932.9k
What is the price of PTGX shares?
As of July 03, 2025, the stock is trading at USD 50.69 with a total of 1,219,430 shares traded.
Over the past week, the price has changed by -6.89%, over one month by +1.08%, over three months by +5.17% and over the past year by +46.55%.
Is Protagonist Therapeutics a good stock to buy?
Partly, yes. Based on ValueRay´s Analyses, Protagonist Therapeutics (NASDAQ:PTGX) is currently (July 2025) ok to buy, but has to be watched. It has a Growth Technical Rating of 51.31 and therefor an somewhat technical positive rating according to historical growth.
Based on momentum, paid dividends and discounted-cash-flow analyses, the fair value of PTGX is around 49.94 USD . This means that PTGX is currently overvalued and has a potential downside of -1.48%.
Is PTGX a buy, sell or hold?
Protagonist Therapeutics has received a consensus analysts rating of 4.40. Therefore, it is recommended to buy PTGX.
  • Strong Buy: 5
  • Buy: 4
  • Hold: 1
  • Sell: 0
  • Strong Sell: 0
What are the forecasts for PTGX share price target?
According to our own proprietary Forecast Model, PTGX Protagonist Therapeutics will be worth about 56.3 in July 2026. The stock is currently trading at 50.69. This means that the stock has a potential upside of +11.05%.
Issuer Target Up/Down from current
Wallstreet Target Price 69 36.1%
Analysts Target Price 68.7 35.5%
ValueRay Target Price 56.3 11%