RLAY Stock Analysis: Relay Therapeutics | NASDAQ

Biotechnology | NASDAQ, USA | Market Cap: 4.172m USD | 12M Return: 358% | US75943R1023 | Charts, Fundamentals & Technical Analysis

Oncology, Genetic Disease, PI3K Inhibitor, Chaperone Therapy
Total Rating 46
Safety 58
Buy Signal -0.10
Biotechnology
Industry Rotation: -10.0
Market Cap: 4.17B
Avg Turnover: 50.3M
Risk 3d forecast
Volatility64.2%
VaR 5th Pctl10.6%
VaR vs Median-0.17%
Reward TTM
Sharpe Ratio2.50
Rel. Str. IBD99.1
Rel. Str. Peer Group90.8
Character TTM
Beta1.744
Beta Downside0.753
Hurst Exponent0.591
Drawdowns 3y
Max DD83.43%
CAGR/Max DD0.32
CAGR/Mean DD0.68
EPS (Earnings per Share) EPS (Earnings per Share) of RLAY over the last years for every Quarter: "2021-09": -0.63, "2021-12": -0.62, "2022-03": -0.57, "2022-06": -0.71, "2022-09": -0.76, "2022-12": -0.56, "2023-03": -0.78, "2023-06": -0.81, "2023-09": -0.54, "2023-12": -0.67, "2024-03": -0.62, "2024-06": -0.69, "2024-09": -0.63, "2024-12": -0.45, "2025-03": -0.46, "2025-06": -0.41, "2025-09": -0.43, "2025-12": -0.32, "2026-03": -0.41, "2026-06": -0.41,
Last SUE: 0.00
Qual. Beats: 0
Revenue Revenue of RLAY over the last years for every Quarter: 2021-09: 0.666, 2021-12: 0.567, 2022-03: 0.419, 2022-06: 0.365, 2022-09: 0.344, 2022-12: 0.253, 2023-03: 0.226, 2023-06: 0.119, 2023-09: 25.202, 2023-12: -0.001, 2024-03: 10.007, 2024-06: 0, 2024-09: 0, 2024-12: 0, 2025-03: 7.679, 2025-06: 0.677, 2025-09: 0, 2025-12: 7, 2026-03: 3, 2026-06: 0.35,
Rev. CAGR: -35.84%
Rev. Trend: -68.7%
Last SUE: -0.12
Qual. Beats: 0

Warnings

Strong Share Dilution
Below Avwap Earnings

Tailwinds

Rs Leader
Idiosyncratic Leader

Seasonality 6 years of data

Jan -7.4% 10
Feb +9.3% 11
Mar -8.7% 13
Apr -13.4% 11
May -0.7% 9
Jun +14.3% 54
Jul +7.0% 20
Aug +3.8% 10
Sep +3.6% 10
Oct -1.7% 10
Nov -6.9% 11
Dec +2.1% 10

How good or bad each month usually is (without trend). The score below shows how much you can trust it: 0 = pure chance, >40 gets interesting and >55 is strong.

Description: RLAY Relay Therapeutics

Relay Therapeutics is a clinical-stage precision medicines company that leverages computational analysis of protein motion to discover small molecule therapeutics, with a primary focus on targeted oncology and genetic diseases. Its drug discovery platform is built around long collaboration with D. E. Shaw Research, whose high-performance computing capabilities model protein dynamics to inform compound design. The company is headquartered in Cambridge, Massachusetts, was incorporated in 2015, and completed its IPO on NASDAQ in July 2020.

The companys lead clinical programs include RLY-2608, a pan-mutant and isoform-selective PI3Kα inhibitor being developed for breast cancer, solid tumors, and vascular malformations; lirafugratinib (RLY-4008), a receptor tyrosine kinase inhibitor for cancer; RLY-8161, an oncogene driver candidate targeting the RAS family; and an alpha-Galactosidase A (aGal) chaperone for Fabry disease. RLAY-2608 is being advanced in combination with fulvestrant and atirmociclib under a collaboration with Pfizer, while RLY-4008 is being developed and commercialized in partnership with Elevar Therapeutics.

Operating within the GICS Biotechnology sub-industry, Relay Therapeutics fits the typical clinical-stage biotech profile: it has no approved products on the market and its valuation is primarily driven by pipeline progress and partnership milestones rather than recurring revenue. Mid-cap status and a recent IPO reflect a company still pre-commercial, with cash runway and clinical readouts serving as the key near-term catalysts for shareholders.

Headlines to Watch Out For
  • RLY-2608 breast cancer data readout remains primary stock catalyst
  • Cash burn from clinical-stage operations risks future equity dilution
  • Pfizer partnership validates RLY-2608 combination development strategy
Piotroski VR-10 (Strict) 1.0
Net Income: -286.0m TTM > 0 and > 6% of Revenue
FCF/TA: -0.22 > 0.02 and ΔFCF/TA 14.02 > 1.0
NWC/Revenue: 8.48k% < 20% (prev 7.75k%; Δ 722.8% < -1%)
CFO/TA -0.22 > 3% & CFO -212.2m > Net Income -286.0m
Net Debt/EBITDA: error (EBITDA <= 0)
Current Ratio: 18.27 > 1.5 & < 3
Outstanding Shares: last quarter (202.8m) vs 12m ago 18.44% < -2%
Gross Margin: 65.63% > 18% (prev -3.68k%; Δ 3.74k% > 0.5%)
Asset Turnover: 1.22% > 50% (prev 1.15%; Δ 0.07% > 0%)
Interest Coverage Ratio: error (cannot be calculated; needs correct EBIT TTM and Interest Expense TTM)
Altman Z'' 8.43
A: 0.91 (Total Current Assets 928.1m - Total Current Liabilities 50.8m) / Total Assets 967.5m
B: -2.24 (Retained Earnings -2.17b / Total Assets 967.5m)
C: -0.34 (EBIT TTM -286.0m / Avg Total Assets 848.1m)
D: 11.49 (Book Value of Equity 890.0m / Total Liabilities 77.4m)
Altman-Z'' = 8.43 = AAA
What is the price of RLAY shares?

As of September 17, 2026, the stock is trading at USD 18.87 with a total of 4,164,326 shares traded. Over the past week, the price has changed by -0.74%, over one month by -5.60%, over three months by +32.51% and over the past year by +358.01%.

Current recommended Stop Loss: 17.20 (which is 8.9% or 1.8 ATR below the current price).

Is RLAY a buy, sell or hold?

Relay Therapeutics has received a consensus analysts rating of 4.31. Therefore, it is recommended to buy RLAY.

  • StrongBuy: 6
  • Buy: 5
  • Hold: 2
  • Sell: 0
  • StrongSell: 0

What are the forecasts/targets for the RLAY price?
Analysts Target Price 27.1 43.5%
Relay Therapeutics (RLAY) - Fundamental Data Overview as of 14 September 2026
Market Cap USD = 4.17b (4.17b USD * 1.0 USD.USD)
P/S = 403.1359
P/B = 4.5601
Revenue TTM = 10.3m USD
EBIT TTM = -286.0m USD
EBITDA TTM = -283.8m USD
Long Term Debt = 26.6m USD (estimated: total debt 30.7m - short term 4.01m)
Short Term Debt = 4.01m USD (from shortTermDebt, last quarter)
Debt = 30.7m USD (from shortLongTermDebtTotal, last quarter) (leases 30.7m already included)
Net Debt = -880.3m USD (calculated: Debt 30.7m - CCE 910.9m)
Enterprise Value = 3.29b USD (4.17b + Debt 30.7m - CCE 910.9m)
 Interest Coverage Ratio = unknown (Ebit TTM -286.0m / Interest Expense TTM 0.0)
 EV/FCF = -15.51x (Enterprise Value 3.29b / FCF TTM -212.2m)
FCF Yield = -6.45% (FCF TTM -212.2m / Enterprise Value 3.29b)
 FCF Margin = -2.05k% (FCF TTM -212.2m / Revenue TTM 10.3m)
 Net Margin = -2.76k% (Net Income TTM -286.0m / Revenue TTM 10.3m)
 Gross Margin = 65.63% ((Revenue TTM 10.3m - Cost of Revenue TTM 3.56m) / Revenue TTM)
Gross Margin QoQ = none% (prev 83.20%)
Tobins Q-Ratio = 3.40 (Enterprise Value 3.29b / Total Assets 967.5m)
Interest Expense / Debt = 0.0% (Interest Expense 0.0 / Debt 30.7m)
Taxrate = 21.0% (US federal default 21%)
NOPAT = -226.0m (EBIT -286.0m * (1 - 21.00%)) [loss with tax shield]
Current Ratio = 18.27 (Total Current Assets 928.1m / Total Current Liabilities 50.8m)
Debt / Equity = 0.03 (Debt 30.7m / totalStockholderEquity, last quarter 890.0m)
 Debt / EBITDA = 3.10 (negative EBITDA) (Net Debt -880.3m / EBITDA -283.8m)
 Debt / FCF = 4.15 (negative FCF - burning cash) (Net Debt -880.3m / FCF TTM -212.2m)
 Total Stockholder Equity = 676.7m (last 4 quarters mean from totalStockholderEquity)
RoA = -33.72% (Net Income -286.0m / Total Assets 967.5m)
RoE = -42.27% (Net Income TTM -286.0m / Total Stockholder Equity 676.7m)
RoCE = -40.67% (EBIT -286.0m / Capital Employed (Equity 676.7m + L.T.Debt 26.6m))
 RoIC = -24.56% (negative operating profit) (NOPAT -226.0m / Invested Capital 920.1m)
 WACC = 12.03% (E(4.17b)/V(4.20b) * Re(12.12%) + D(30.7m)/V(4.20b) * Rd(0.0%) * (1-Tc(0.21)))
Discount Rate = 12.12% (= CAPM, Blume Beta Adj.)
Shares (quarterly) Correlation: 93.28 | Cagr: 21.52%
 [DCF] Fair Price = unknown (Cash Flow -212.2m)
 EPS Correlation: N/A | EPS CAGR: N/A | SUE: 0.0 | # QB: 0
Revenue Correlation: -68.70 | Revenue CAGR: -35.84% | SUE: -0.12 | # QB: 0
EPS current Quarter (2026-09-30): EPS=-0.40 | Chg30d=-3.68% | Revisions=-10% | Analysts=12
EPS current Year (2026-12-31): EPS=-1.62 | Chg30d=-5.86% | Revisions=-58% | GrowthEPS=-0.4% | GrowthRev=-31.4%
EPS next Year (2027-12-31): EPS=-1.64 | Chg30d=+0.21% | Revisions=+25% | GrowthEPS=-1.3% | GrowthRev=+57.2%
[Analyst] Revisions Ratio: -35% (up=5, down=12)