(RLAY) Relay Therapeutics - Overview

Exchange: NASDAQ • Country: United States • Currency: USD • Type: Common Stock • ISIN: US75943R1023

Stock: RLY-2608, RLY-4008, RLY-8161, RLY-1013, AGAL Chaperone

Total Rating 53
Risk 67
Buy Signal 0.92

EPS (Earnings per Share)

EPS (Earnings per Share) of RLAY over the last years for every Quarter: "2020-12": 0.7, "2021-03": -0.47, "2021-06": -2.1, "2021-09": -0.66, "2021-12": -0.62, "2022-03": -0.57, "2022-06": -0.71, "2022-09": -0.76, "2022-12": -0.56, "2023-03": -0.78, "2023-06": -0.81, "2023-09": -0.54, "2023-12": -0.67, "2024-03": -0.62, "2024-06": -0.69, "2024-09": -0.63, "2024-12": -0.45, "2025-03": -0.4554, "2025-06": -0.41, "2025-09": -0.43, "2025-12": 0,

Revenue

Revenue of RLAY over the last years for every Quarter: 2020-12: 82.654, 2021-03: 0.952, 2021-06: 0.844, 2021-09: 0.666, 2021-12: 0.567, 2022-03: 0.419, 2022-06: 0.365, 2022-09: 0.344, 2022-12: 0.253, 2023-03: 0.226, 2023-06: 0.119, 2023-09: 25.202, 2023-12: -0.001, 2024-03: 10.007, 2024-06: 0, 2024-09: 0, 2024-12: 0, 2025-03: 7.679, 2025-06: 0.677, 2025-09: 0, 2025-12: null,
Risk 5d forecast
Volatility 73.6%
Relative Tail Risk -9.20%
Reward TTM
Sharpe Ratio 1.22
Alpha 61.16
Character TTM
Beta 1.816
Beta Downside 1.705
Drawdowns 3y
Max DD 89.78%
CAGR/Max DD -0.26

Description: RLAY Relay Therapeutics December 26, 2025

Relay Therapeutics (NASDAQ:RLAY) is a clinical-stage precision-medicine firm that leverages computational protein-motion modeling to discover small-molecule therapeutics for oncology and genetic diseases. Its lead pipeline includes RLY-2608, a pan-mutant PI3Kα inhibitor being evaluated in breast cancer, solid tumors, and vascular malformations; aGal chaperone for Fabry disease; RLY-8161 targeting RAS-driven cancers; RLY-1013, an estrogen-receptor-alpha degrader; and lirafugratinib (RLY-4008), a receptor-tyrosine-kinase inhibitor. The company partners with D.E. Shaw Research for advanced modeling, Elevar Therapeutics for RLY-4008 commercialization, and Pfizer on a RLY-2608 + fulvestrant/atiraciclib combo.

Key recent metrics: as of Q3 2024, Relay reported cash and equivalents of roughly $350 million, giving it an estimated 18-month runway at current burn (~$20 million per quarter). The PI3K inhibitor market is projected to exceed $6 billion by 2028, providing a sizable addressable space for RLY-2608. Additionally, the biotech sector’s R&D intensity remains high, with average R&D spend as a % of revenue at ~45 % for comparable clinical-stage firms, underscoring the importance of efficient discovery platforms like Relay’s.

For a deeper, data-driven view of Relay’s valuation and risk profile, check out the ValueRay analysis.

Piotroski VR‑10 (Strict, 0-10) 1.0

Net Income: -297.6m TTM > 0 and > 6% of Revenue
FCF/TA: -0.37 > 0.02 and ΔFCF/TA -6.76 > 1.0
NWC/Revenue: 7078 % < 20% (prev 8177 %; Δ -1099 % < -1%)
CFO/TA -0.37 > 3% & CFO -248.5m > Net Income -297.6m
Net Debt/EBITDA: error (EBITDA <= 0)
Current Ratio: 19.14 > 1.5 & < 3
Outstanding Shares: last quarter (172.4m) vs 12m ago 22.93% < -2%
Gross Margin: 63.09% > 18% (prev 0.45%; Δ 6264 % > 0.5%)
Asset Turnover: 1.04% > 50% (prev 1.08%; Δ -0.03% > 0%)
Interest Coverage Ratio: -13.80 > 6 (EBITDA TTM -316.6m / Interest Expense TTM -23.3m)

Altman Z'' -15.00

A: 0.88 (Total Current Assets 624.0m - Total Current Liabilities 32.6m) / Total Assets 670.0m
B: -2.93 (Retained Earnings -1.96b / Total Assets 670.0m)
C: -0.40 (EBIT TTM -320.8m / Avg Total Assets 800.1m)
D: -31.45 (Book Value of Equity -1.96b / Total Liabilities 62.3m)
Altman-Z'' Score: -39.47 = D

What is the price of RLAY shares?

As of February 07, 2026, the stock is trading at USD 8.92 with a total of 3,455,733 shares traded.
Over the past week, the price has changed by +16.45%, over one month by +9.18%, over three months by +36.60% and over the past year by +97.78%.

Is RLAY a buy, sell or hold?

Relay Therapeutics has received a consensus analysts rating of 4.31. Therefore, it is recommended to buy RLAY.
  • StrongBuy: 6
  • Buy: 5
  • Hold: 2
  • Sell: 0
  • StrongSell: 0

What are the forecasts/targets for the RLAY price?

Issuer Target Up/Down from current
Wallstreet Target Price 14.6 63.1%
Analysts Target Price 14.6 63.1%
ValueRay Target Price 9.8 9.4%

RLAY Fundamental Data Overview February 03, 2026

P/S = 158.9048
P/B = 2.189
Revenue TTM = 8.36m USD
EBIT TTM = -320.8m USD
EBITDA TTM = -316.6m USD
Long Term Debt = 33.3m USD (from capitalLeaseObligations, last quarter)
Short Term Debt = 3.64m USD (from shortTermDebt, last quarter)
Debt = 33.3m USD (from shortLongTermDebtTotal, last quarter)
Net Debt = -58.2m USD (from netDebt column, last quarter)
Enterprise Value = 764.5m USD (1.33b + Debt 33.3m - CCE 596.4m)
Interest Coverage Ratio = -13.80 (Ebit TTM -320.8m / Interest Expense TTM -23.3m)
EV/FCF = -3.07x (Enterprise Value 764.5m / FCF TTM -248.9m)
FCF Yield = -32.55% (FCF TTM -248.9m / Enterprise Value 764.5m)
FCF Margin = -2978 % (FCF TTM -248.9m / Revenue TTM 8.36m)
Net Margin = -3561 % (Net Income TTM -297.6m / Revenue TTM 8.36m)
Gross Margin = 63.09% ((Revenue TTM 8.36m - Cost of Revenue TTM 3.08m) / Revenue TTM)
Gross Margin QoQ = none% (prev -48.01%)
Tobins Q-Ratio = 1.14 (Enterprise Value 764.5m / Total Assets 670.0m)
Interest Expense / Debt = 20.82% (Interest Expense 6.94m / Debt 33.3m)
Taxrate = 21.0% (US default 21%)
NOPAT = -253.5m (EBIT -320.8m * (1 - 21.00%)) [loss with tax shield]
Current Ratio = 19.14 (Total Current Assets 624.0m / Total Current Liabilities 32.6m)
Debt / Equity = 0.05 (Debt 33.3m / totalStockholderEquity, last quarter 607.7m)
Debt / EBITDA = 0.18 (negative EBITDA) (Net Debt -58.2m / EBITDA -316.6m)
Debt / FCF = 0.23 (negative FCF - burning cash) (Net Debt -58.2m / FCF TTM -248.9m)
Total Stockholder Equity = 693.1m (last 4 quarters mean from totalStockholderEquity)
RoA = -37.20% (Net Income -297.6m / Total Assets 670.0m)
RoE = -42.94% (Net Income TTM -297.6m / Total Stockholder Equity 693.1m)
RoCE = -44.17% (EBIT -320.8m / Capital Employed (Equity 693.1m + L.T.Debt 33.3m))
RoIC = -36.57% (negative operating profit) (NOPAT -253.5m / Invested Capital 693.1m)
WACC = 12.70% (E(1.33b)/V(1.36b) * Re(12.61%) + D(33.3m)/V(1.36b) * Rd(20.82%) * (1-Tc(0.21)))
Discount Rate = 12.61% (= CAPM, Blume Beta Adj.)
Shares Correlation 3-Years: 100.0 | Cagr: 18.59%
Fair Price DCF = unknown (Cash Flow -248.9m)
EPS Correlation: 69.53 | EPS CAGR: 32.87% | SUE: 4.0 | # QB: 1
Revenue Correlation: 11.13 | Revenue CAGR: -54.64% | SUE: -0.02 | # QB: 0
EPS next Quarter (2026-03-31): EPS=-0.43 | Chg30d=-0.003 | Revisions Net=+1 | Analysts=6
EPS next Year (2026-12-31): EPS=-1.64 | Chg30d=-0.032 | Revisions Net=+1 | Growth EPS=+6.0% | Growth Revenue=-25.1%

Additional Sources for RLAY Stock

News: Wall Street Journal | Benzinga | Yahoo Finance
Fund Manager Positions: Dataroma | Stockcircle