(SPRO) Spero Therapeutics - Ratings and Ratios

Exchange: NASDAQ • Country: United States • Currency: USD • Type: Common Stock • ISIN: US84833T1034

SPRO EPS (Earnings per Share)

This chart shows the EPS (Earnings per Share) of SPRO over the last 5 years for every Quarter.

SPRO Revenue

This chart shows the Revenue of SPRO over the last 5 years for every Quarter.

SPRO: Antibiotics, Infection Treatments, Pulmonary Disease Treatments

Spero Therapeutics, Inc. is a clinical-stage biopharmaceutical company that focuses on developing innovative treatments for multi-drug resistant bacterial infections and rare diseases. With a pipeline of promising product candidates, the company is poised to address significant unmet medical needs in the US market. Its lead candidate, Tebipenem HBr, is an oral carbapenem-class antibiotic in Phase 3 development for complicated urinary tract infections, including pyelonephritis in adult patients.

The companys product portfolio also includes SPR720, a novel first-line treatment for nontuberculous mycobacterial pulmonary disease, and SPR206, which is being developed in partnership with Everest Medicines for the Greater China, South Korea, and Southeast Asian markets. Speros strategic partnerships, including its license agreement with Meiji Seika Pharma Co., Ltd. for Tebipenem HBr and with Vertex Pharmaceuticals Incorporated for SPR720, underscore its commitment to advancing its pipeline and bringing new treatments to market.

From a technical analysis perspective, Spero Therapeutics stock has shown a relatively stable trading pattern, with its 20-day simple moving average (SMA) at $0.66 and 50-day SMA at $0.70. The stocks current price of $0.68 is near its 52-week low of $0.56, suggesting potential for a rebound. The average true range (ATR) of 9.12% indicates moderate volatility, and a break above the 50-day SMA could signal a bullish trend.

Fundamentally, Spero Therapeutics has a market capitalization of $36.40M USD, with no price-to-earnings ratio due to its current loss-making status. The companys return on equity is -123.50%, reflecting the significant investment in its pipeline. However, as the company advances its product candidates through clinical trials, a successful outcome could lead to a significant increase in valuation. Based on the current technical and fundamental data, a forecast for Spero Therapeutics could be a potential price target of $1.20-$1.50 in the next 6-12 months, driven by positive clinical trial results and strategic partnerships. This represents a potential upside of 76%-121% from current levels.

Additional Sources for SPRO Stock

News: Wall Street Journal | Benzinga | Yahoo Finance
Tweets: X | Stocktwits
Fund Manager Positions: Dataroma | Stockcircle

SPRO Stock Overview

Market Cap in USD 154m
Sector Healthcare
Industry Biotechnology
GiC Sub-Industry Biotechnology
IPO / Inception 2017-11-02

SPRO Stock Ratings

Growth Rating -75.4
Fundamental -32.2
Dividend Rating 0.0
Rel. Strength 131
Analysts 3.33 of 5
Fair Price Momentum 1.86 USD
Fair Price DCF -

SPRO Dividends

Currently no dividends paid

SPRO Growth Ratios

Growth Correlation 3m 25.1%
Growth Correlation 12m -65.1%
Growth Correlation 5y -79.8%
CAGR 5y -24.93%
CAGR/Max DD 5y -0.26
Sharpe Ratio 12m -0.49
Alpha 91.22
Beta 1.537
Volatility 76.55%
Current Volume 2078.6k
Average Volume 20d 2093.2k
What is the price of SPRO shares?
As of June 14, 2025, the stock is trading at USD 2.83 with a total of 2,078,598 shares traded.
Over the past week, the price has changed by +13.20%, over one month by +310.14%, over three months by +263.52% and over the past year by +106.57%.
Is Spero Therapeutics a good stock to buy?
Probably not. Based on ValueRay´s Fundamental Analyses, Spero Therapeutics (NASDAQ:SPRO) is currently (June 2025) not a good stock to buy. It has a ValueRay Fundamental Rating of -32.23 and therefor a somewhat negative outlook according to the companies health.
Based on momentum, paid dividends and discounted-cash-flow analyses, the fair value of SPRO is around 1.86 USD . This means that SPRO is currently overvalued and has a potential downside of -34.28%.
Is SPRO a buy, sell or hold?
Spero Therapeutics has received a consensus analysts rating of 3.33. Therefor, it is recommend to hold SPRO.
  • Strong Buy: 0
  • Buy: 1
  • Hold: 2
  • Sell: 0
  • Strong Sell: 0
What are the forecasts for SPRO share price target?
According to our own proprietary Forecast Model, SPRO Spero Therapeutics will be worth about 2.2 in June 2026. The stock is currently trading at 2.83. This means that the stock has a potential downside of -22.26%.
Issuer Target Up/Down from current
Wallstreet Target Price 5 76.7%
Analysts Target Price 5 76.7%
ValueRay Target Price 2.2 -22.3%