(SRRK) Scholar Rock Holding - Ratings and Ratios

Exchange: NASDAQ • Country: United States • Currency: USD • Type: Common Stock • ISIN: US80706P1030

Monoclonal Antibodies, Inhibitor, Cancer, Spinal Muscular Atrophy

Risk via 10d forecast
Volatility 80.4%
Value at Risk 5%th 114%
Relative Tail Risk -13.47%
Reward TTM
Sharpe Ratio 0.72
Alpha 29.33
Character TTM
Hurst Exponent 0.592
Beta 1.308
Beta Downside 1.767
Drawdowns 3y
Max DD 65.21%
Mean DD 29.18%
Median DD 28.78%

Description: SRRK Scholar Rock Holding November 09, 2025

Scholar Rock Holding Corp. (NASDAQ: SRRK) is a U.S.-based biopharma that leverages its proprietary platform on the transforming growth factor-beta (TGF-β) superfamily to create monoclonal antibodies that selectively bind growth-factor precursors. The company’s scientific premise is that modulating these upstream signals can treat serious diseases where protein growth-factor signaling is a driver.

Its lead assets include Apitegromab, a myostatin-activation inhibitor currently in a Phase 3 trial for spinal muscular atrophy (SMA), and SRK-181, which has completed Phase 1 testing for cancers that are refractory to checkpoint-inhibitor therapies (e.g., anti-PD-1/PD-L1). The pipeline also targets neuromuscular, cardiometabolic, fibrotic, and iron-restricted anemia indications.

**External context (as of 2024):**
• The global SMA market is projected by industry analysts to exceed **$2.5 billion by 2028**, driven by expanding newborn screening and gene-therapy approvals (source: GlobalData, 2024).
• Biotech R&D spending in the United States is growing at a **~10 % CAGR** (2023-2028), reflecting strong capital inflows and a favorable regulatory environment for novel biologics (source: BIO, 2024).
• Scholar Rock reported **≈ $140 million of cash and cash equivalents** in its latest 10-Q filing (Q2 2024), giving it an estimated 12-18 month runway at current burn rates, though this assumes no major acquisition or partnership outlays.**

If you want a data-rich, unbiased view of SRRK’s valuation metrics and how they compare to sector peers, a quick look at ValueRay’s analyst dashboard can provide the next layer of insight.

SRRK Stock Overview

Market Cap in USD 3,596m
Sub-Industry Biotechnology
IPO / Inception 2018-05-24
Return 12m vs S&P 500 22.0%
Analyst Rating 4.60 of 5

SRRK Dividends

Currently no dividends paid

SRRK Growth Ratios

Metric Value
CAGR 3y 69.45%
CAGR/Max DD Calmar Ratio 1.07
CAGR/Mean DD Pain Ratio 2.38
Current Volume 1938.1k
Average Volume 1715.7k

Piotroski VR‑10 (Strict, 0-10) 0.0

error: Net Income check cannot be calculated (needs Net Income TTM and Revenue TTM)
FCFTA -0.67 (>2.0%) and ΔFCFTA 38.72pp (YES ≥ +1.0pp, WARN ≥ +0.5pp)
error: NWC/Revenue cannot be calculated (needs Current Assets/Liabilities and Revenue current+prev)
CFO/TA -0.67 (>3.0%) and CFO -274.1m > Net Income -353.4m (YES >=105%, WARN >=100%)
NO Net Debt/EBITDA fails (EBITDA <= 0)
Current Ratio 6.30 (target 1.5–3.0; WARN 1.2–<1.5 or >3.0–5.0; CFO/TA gate active)
Outstanding Shares last Quarter (113.7m) change vs 12m ago 17.19% (target <= -2.0% for YES)
error: Gross Margin (current vs previous) cannot be calculated (needs Total Revenue and Cost Of Revenue)
Asset Turnover 0.0% (prev 6.51%; Δ -6.51pp) >=50% & Δ>=+2pp (WARN >=35% & Δ>=0)
Interest Coverage Ratio -100.5 (EBITDA TTM -357.6m / Interest Expense TTM 2.54m) >= 6 (WARN >= 3)

Altman Z'' -17.76

(A) 0.80 = (Total Current Assets 390.7m - Total Current Liabilities 62.0m) / Total Assets 411.7m
(B) -2.94 = Retained Earnings (Balance) -1.21b / Total Assets 411.7m
warn (B) unusual magnitude: -2.94 — check mapping/units
(C) -0.86 = EBIT TTM -255.3m / Avg Total Assets 295.4m
(D) -7.25 = Book Value of Equity -1.21b / Total Liabilities 166.7m
Total Rating: -17.76 = (6.56 * A) + (3.26 * B) + (6.72 * C) + (1.05 * D)

ValueRay F-Score (Strict, 0-100) 22.51

1. Piotroski 0.0pt
2. FCF Yield -8.23%
3. FCF Margin data missing
4. Debt/Equity 0.45
5. Debt/Ebitda 0.49
6. ROIC - WACC (= -67.41)%
7. RoE -122.0%
8. Rev. Trend -48.37%
9. EPS Trend -89.32%

What is the price of SRRK shares?

As of November 21, 2025, the stock is trading at USD 38.02 with a total of 1,938,143 shares traded.
Over the past week, the price has changed by +26.44%, over one month by +36.17%, over three months by +10.52% and over the past year by +36.47%.

Is SRRK a buy, sell or hold?

Scholar Rock Holding has received a consensus analysts rating of 4.60. Therefore, it is recommended to buy SRRK.
  • Strong Buy: 6
  • Buy: 4
  • Hold: 0
  • Sell: 0
  • Strong Sell: 0

What are the forecasts/targets for the SRRK price?

Issuer Target Up/Down from current
Wallstreet Target Price 47.7 25.5%
Analysts Target Price 47.7 25.5%
ValueRay Target Price 36.7 -3.5%

SRRK Fundamental Data Overview November 18, 2025

Market Cap USD = 3.60b (3.60b USD * 1.0 USD.USD)
P/S = 13.1358
P/B = 15.4146
Beta = 0.662
Revenue TTM = 0.0 USD
EBIT TTM = -255.3m USD
EBITDA TTM = -357.6m USD
Long Term Debt = 50.1m USD (from longTermDebt, last fiscal year)
Short Term Debt = 5.33m USD (from shortTermDebt, last quarter)
Debt = 110.1m USD (from shortLongTermDebtTotal, last quarter)
Net Debt = -176.7m USD (from netDebt column, last quarter)
Enterprise Value = 3.34b USD (3.60b + Debt 110.1m - CCE 369.6m)
Interest Coverage Ratio = -100.5 (Ebit TTM -255.3m / Interest Expense TTM 2.54m)
FCF Yield = -8.23% (FCF TTM -274.6m / Enterprise Value 3.34b)
FCF Margin = unknown (Revenue TTM is 0 or missing)
Net Margin = unknown
Gross Margin = unknown ((Revenue TTM 0.0 - Cost of Revenue TTM 812.0k) / Revenue TTM)
Tobins Q-Ratio = 8.10 (Enterprise Value 3.34b / Total Assets 411.7m)
Interest Expense / Debt = 1.21% (Interest Expense 1.33m / Debt 110.1m)
Taxrate = 21.0% (US default 21%)
NOPAT = -201.7m (EBIT -255.3m * (1 - 21.00%)) [loss with tax shield]
Current Ratio = 6.30 (Total Current Assets 390.7m / Total Current Liabilities 62.0m)
Debt / Equity = 0.45 (Debt 110.1m / totalStockholderEquity, last quarter 245.0m)
Debt / EBITDA = 0.49 (negative EBITDA) (Net Debt -176.7m / EBITDA -357.6m)
Debt / FCF = 0.64 (negative FCF - burning cash) (Net Debt -176.7m / FCF TTM -274.6m)
Total Stockholder Equity = 289.8m (last 4 quarters mean from totalStockholderEquity)
RoA = -85.84% (Net Income -353.4m / Total Assets 411.7m)
RoE = -122.0% (Net Income TTM -353.4m / Total Stockholder Equity 289.8m)
RoCE = -75.09% (EBIT -255.3m / Capital Employed (Equity 289.8m + L.T.Debt 50.1m))
RoIC = -56.87% (negative operating profit) (NOPAT -201.7m / Invested Capital 354.6m)
WACC = 10.55% (E(3.60b)/V(3.71b) * Re(10.84%) + D(110.1m)/V(3.71b) * Rd(1.21%) * (1-Tc(0.21)))
Discount Rate = 10.84% (= CAPM, Blume Beta Adj.)
Shares Correlation 3-Years: 100.0 | Cagr: 22.35%
Fair Price DCF = unknown (Cash Flow -274.6m)
EPS Correlation: -89.32 | EPS CAGR: -40.42% | SUE: -0.47 | # QB: 0
Revenue Correlation: -48.37 | Revenue CAGR: -61.68% | SUE: 0.0 | # QB: 0

Additional Sources for SRRK Stock

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Fund Manager Positions: Dataroma | Stockcircle