TECX Stock Analysis: Tectonic Therapeutic | NASDAQ

Biotechnology | NASDAQ, USA | Market Cap: 528m USD | 12M Return: 60.9% | US8789721086 | Charts, Fundamentals & Technical Analysis

TX45, TX2100, Bispecifics, GPCR Modulators
Total Rating 35
Safety 49
Buy Signal -0.69
Biotechnology
Industry Rotation: -19.3
Market Cap: 528M
Avg Turnover: 5.72M
Risk 3d forecast
Volatility75.8%
VaR 5th Pctl10.9%
VaR vs Median-10.1%
Reward TTM
Sharpe Ratio0.94
Rel. Str. IBD40
Rel. Str. Peer Group31
Character TTM
Beta1.661
Beta Downside1.416
Hurst Exponent0.522
Drawdowns 3y
Max DD73.25%
CAGR/Max DD0.13
CAGR/Mean DD0.26

Warnings

Interest Coverage Ratio Critical
Below Avwap Earnings
Below Sma 200d

Tailwinds

Seasonal Tailwind

Seasonality 8.3 years of data

Jan -1.1% 9
Feb -14.2% 7
Mar -2.9% 9
Apr -7.2% 39
May +7.9% 10
Jun -4.1% 18
Jul +5.9% 29
Aug +1.5% 15
Sep -16.9% 42
Oct +10.1% 62
Nov +9.5% 11
Dec +0.8% 6

How good or bad each month usually is (without trend). The score below shows how much you can trust it: 0 = pure chance, >40 gets interesting and >55 is strong.

Description: TECX Tectonic Therapeutic

Tectonic Therapeutic, Inc. (NASDAQ: TECX) is a clinical-stage biotechnology company focused on discovering and developing therapeutic proteins and antibodies that target G protein-coupled receptors (GPCRs), one of the largest and most validated classes of drug targets in human disease. The company leverages its proprietary GEODe technology platform to engineer biologic medicines aimed at GPCRs that have historically been difficult to address with traditional small-molecule approaches. Its lead candidate, TX45, is an Fc-relaxin fusion molecule designed to activate the RXFP1 receptor for the treatment of cardiovascular disease associated with heart failure with preserved ejection fraction (HFpEF).

In addition to TX45, Tectonic is advancing a pipeline that includes TX2100 for hereditary hemorrhagic telangiectasia (HHT), a bispecific GPCR modulator for fibrosis, and other early-stage GPCR-targeted programs. Like many development-stage biotechnology companies, Tectonic is headquartered in Watertown, Massachusetts, a region anchored by the Greater Boston life sciences cluster, and operates as a small-cap company within the broader healthcare sector. Its business model is centered on translating its platform and pipeline candidates into partnerships, licensing agreements, or commercialized products, with revenue largely dependent on future clinical and regulatory milestones rather than current product sales.

Headlines to Watch Out For
  • TX45 Phase 2 pulmonary hypertension data readout approaches
  • Cash runway extension through key clinical milestones
  • Pipeline expansion advances with TX2100 HHT program
  • Partnership deals could validate GEODe GPCR platform
Piotroski VR-10 (Strict) 0.0
Net Income: error (cannot be calculated; needs Net Income TTM and Revenue TTM)
FCF/TA: -0.31 > 0.02 and ΔFCF/TA -8.74 > 1.0
NWC/Revenue: error (cannot be calculated; needs Current Assets/Liabilities and Revenue current+prev)
CFO/TA -0.30 > 3% & CFO -72.1m > Net Income -85.8m
Net Debt/EBITDA: error (EBITDA <= 0)
Current Ratio: 22.29 > 1.5 & < 3
Outstanding Shares: last quarter (19.0m) vs 12m ago 1.52% < -2%
Gross Margin: error (current vs previous; cannot be calculated due to missing/invalid data or negative margin)
Asset Turnover: 0.0% > 50% (prev 0.0%; Δ 0.0% > 0%)
Interest Coverage Ratio: -2.14k > 6 (EBIT TTM -85.4m / Interest Expense TTM 40.0k)
Altman Z'' 10.00
A: 0.93 (Total Current Assets 231.1m - Total Current Liabilities 10.4m) / Total Assets 237.0m
B: -1.14 (Retained Earnings -270.3m / Total Assets 237.0m)
C: -0.32 (EBIT TTM -85.4m / Avg Total Assets 266.2m)
D: 16.97 (Book Value of Equity 223.8m / Total Liabilities 13.2m)
Altman-Z'' = 18.06 = AAA
What is the price of TECX shares?

As of September 25, 2026, the stock is trading at USD 24.12 with a total of 214,408 shares traded. Over the past week, the price has changed by -11.36%, over one month by -33.86%, over three months by -21.48% and over the past year by +60.91%.

Current recommended Stop Loss: 21.90 (which is 9.2% or 1.2 ATR below the current price).

Is TECX a buy, sell or hold?

Tectonic Therapeutic has received a consensus analysts rating of 4.83. Therefore, it is recommended to buy TECX.

  • StrongBuy: 5
  • Buy: 1
  • Hold: 0
  • Sell: 0
  • StrongSell: 0

What are the forecasts/targets for the TECX price?
Analysts Target Price 76.6 217.7%
Tectonic Therapeutic (TECX) - Fundamental Data Overview as of 22 September 2026
Market Cap USD = 527.8m (527.8m USD * 1.0 USD.USD)
P/B = 2.3563
Revenue TTM = 0.0 USD
EBIT TTM = -85.4m USD
EBITDA TTM = -83.8m USD
Long Term Debt = 2.82m USD (estimated: total debt 4.40m - short term 1.58m)
Short Term Debt = 1.58m USD (from shortTermDebt, last quarter)
Debt = 4.40m USD (from shortLongTermDebtTotal, last quarter) (leases 4.40m already included)
Net Debt = -222.7m USD (calculated: Debt 4.40m - CCE 227.1m)
Enterprise Value = 305.2m USD (527.8m + Debt 4.40m - CCE 227.1m)
Interest Coverage Ratio = -2.14k (Ebit TTM -85.4m / Interest Expense TTM 40.0k)
EV/FCF = -4.21x (Enterprise Value 305.2m / FCF TTM -72.4m)
FCF Yield = -23.74% (FCF TTM -72.4m / Enterprise Value 305.2m)
 FCF Margin = unknown (Revenue TTM is 0 or missing)
 Net Margin = unknown
 Gross Margin = unknown ((Revenue TTM 0.0 - Cost of Revenue TTM 0.0) / Revenue TTM)
 Tobins Q-Ratio = 1.29 (Enterprise Value 305.2m / Total Assets 237.0m)
Interest Expense / Debt = 0.91% (Interest Expense 40.0k / Debt 4.40m)
Taxrate = 21.0% (US federal default 21%)
NOPAT = -67.5m (EBIT -85.4m * (1 - 21.00%)) [loss with tax shield]
Current Ratio = 22.29 (Total Current Assets 231.1m / Total Current Liabilities 10.4m)
Debt / Equity = 0.02 (Debt 4.40m / totalStockholderEquity, last quarter 223.8m)
 Debt / EBITDA = 2.66 (negative EBITDA) (Net Debt -222.7m / EBITDA -83.8m)
 Debt / FCF = 3.07 (negative FCF - burning cash) (Net Debt -222.7m / FCF TTM -72.4m)
 Total Stockholder Equity = 243.3m (last 4 quarters mean from totalStockholderEquity)
RoA = -32.23% (Net Income -85.8m / Total Assets 237.0m)
RoE = -35.26% (Net Income TTM -85.8m / Total Stockholder Equity 243.3m)
RoCE = -34.71% (EBIT -85.4m / Capital Employed (Equity 243.3m + L.T.Debt 2.82m))
 RoIC = -29.56% (negative operating profit) (NOPAT -67.5m / Invested Capital 228.2m)
 WACC = 11.74% (E(527.8m)/V(532.2m) * Re(11.83%) + D(4.40m)/V(532.2m) * Rd(0.91%) * (1-Tc(0.21)))
Discount Rate = 11.83% (= CAPM, Blume Beta Adj.)
Shares (quarterly) Correlation: 77.93 | Cagr: 105.9%
 [DCF] Fair Price = unknown (Cash Flow -72.4m)
 EPS Correlation: N/A | EPS CAGR: N/A | SUE: 0.21 | # QB: 0
Revenue Correlation: N/A | Revenue CAGR: N/A | SUE: 0.0 | # QB: 0
EPS current Quarter (2026-09-30): EPS=-1.33 | Chg30d=+2.83% | Revisions=-25% | Analysts=8
EPS current Year (2026-12-31): EPS=-5.09 | Chg30d=-0.03% | Revisions=+25% | GrowthEPS=-25.8% | GrowthRev=+0.0%
EPS next Year (2027-12-31): EPS=-5.38 | Chg30d=+0.50% | Revisions=-25% | GrowthEPS=-5.7% | GrowthRev=+0.0%
[Analyst] Revisions Ratio: -17% (up=1, down=2)