(TNGX) Tango Therapeutics - Overview

Sector: Healthcare | Industry: Biotechnology | Exchange: NASDAQ (USA) | Market Cap: 3.068m USD | Total Return: 985.3% in 12m

Oncology Drugs, PRMT5 Inhibitors, Precision Medicines, Cancer Therapies
Total Rating 46
Safety 72
Buy Signal -0.45
Biotechnology
Industry Rotation: -8.2
Market Cap: 3.07B
Avg Turnover: 69.3M
Risk 3d forecast
Volatility89.4%
VaR 5th Pctl14.2%
VaR vs Median-3.87%
Reward TTM
Sharpe Ratio3.01
Rel. Str. IBD99.3
Rel. Str. Peer Group96.3
Character TTM
Beta1.061
Beta Downside0.042
Hurst Exponent0.486
Drawdowns 3y
Max DD91.46%
CAGR/Max DD1.05
CAGR/Mean DD2.63
EPS (Earnings per Share) EPS (Earnings per Share) of TNGX over the last years for every Quarter: "2021-03": -0.01, "2021-06": -0.16, "2021-09": -0.28, "2021-12": -0.25, "2022-03": -0.29, "2022-06": -0.28, "2022-09": -0.33, "2022-12": -0.33, "2023-03": -0.32, "2023-06": -0.23, "2023-09": -0.23, "2023-12": -0.32, "2024-03": -0.35, "2024-06": -0.24, "2024-09": -0.27, "2024-12": -0.34, "2025-03": -0.36, "2025-06": -0.35, "2025-09": -0.14, "2025-12": -0.29, "2026-03": -0.32,
Last SUE: -0.38
Qual. Beats: 0
Revenue Revenue of TNGX over the last years for every Quarter: 2021-03: 6.386, 2021-06: 18.153, 2021-09: 6.787, 2021-12: 5.716, 2022-03: 5.758, 2022-06: 5.771, 2022-09: 6.92, 2022-12: 6.411, 2023-03: 5.766, 2023-06: 14.598, 2023-09: 10.732, 2023-12: 5.431, 2024-03: 6.471, 2024-06: 19.875, 2024-09: 11.607, 2024-12: 4.117, 2025-03: 5.392, 2025-06: 3.181, 2025-09: 53.811, 2025-12: 0, 2026-03: 0,
Rev. CAGR: 18.74%
Rev. Trend: 55.5%
Last SUE: -0.09
Qual. Beats: 0

Warnings

Share dilution 30.2% YoY

Altman Z'' -15.00 < 1.0 - financial distress zone

Below Avwap Earnings

Tailwinds

Leader

Description: TNGX Tango Therapeutics

Tango Therapeutics, Inc. (TNGX) is a Boston-based biotechnology firm specializing in precision oncology through the discovery and development of targeted therapies. The company’s primary clinical focus centers on methylthioadenosine-cooperative PRMT5 inhibitors, specifically TNG462 for solid tumors and the brain-penetrant TNG456 for glioblastoma. Additionally, the company is advancing TNG260 to address immune evasion in lung cancer patients with STK11 mutations.

The precision oncology sector utilizes a synthetic lethality approach, identifying genetic vulnerabilities in cancer cells to create drugs that spare healthy tissue. This business model typically involves high research and development costs during early-phase clinical trials before seeking regulatory approval or strategic partnerships with larger pharmaceutical entities. Investors may find additional context on these industry trends at ValueRay.

Headlines to Watch Out For
  • Clinical trial results for PRMT5 inhibitor TNG462 drive valuation in pancreatic cancer
  • Glioblastoma data for brain-penetrant TNG456 determines expansion into central nervous system markets
  • Development of TNG260 addresses high unmet need in STK11-mutant lung cancer populations
  • Cash runway and burn rate dictate timing of future dilutive equity offerings
  • Regulatory approval pathways for precision oncology candidates influence long-term revenue projections
Piotroski VR-10 (Strict) 0.0
Net Income: -107.2m TTM > 0 and > 6% of Revenue
FCF/TA: -0.17 > 0.02 and ΔFCF/TA 19.33 > 1.0
NWC/Revenue: 663.2% < 20% (prev 461.1%; Δ 202.1% < -1%)
CFO/TA -0.32 > 3% & CFO -141.5m > Net Income -107.2m
Net Debt/EBITDA: error (EBITDA <= 0)
Current Ratio: 27.38 > 1.5 & < 3
Outstanding Shares: last quarter (143.6m) vs 12m ago 30.17% < -2%
Gross Margin: error (current vs previous; cannot be calculated due to missing/invalid data or negative margin)
Asset Turnover: 16.05% > 50% (prev 14.94%; Δ 1.11% > 0%)
Interest Coverage Ratio: error (cannot be calculated; needs correct EBITDA TTM and Interest Expense TTM)
Altman Z'' -15.00
A: 0.87 (Total Current Assets 392.3m - Total Current Liabilities 14.3m) / Total Assets 435.8m
B: -1.49 (Retained Earnings -648.7m / Total Assets 435.8m)
C: -0.32 (EBIT TTM -115.4m / Avg Total Assets 355.0m)
D: -14.65 (Book Value of Equity -648.6m / Total Liabilities 44.3m)
Altman-Z'' = -16.73 = D
What is the price of TNGX shares?

As of May 24, 2026, the stock is trading at USD 21.62 with a total of 2,499,710 shares traded.
Over the past week, the price has changed by -1.56%, over one month by -24.87%, over three months by +58.99% and over the past year by +985.25%.

Is TNGX a buy, sell or hold?

Tango Therapeutics has received a consensus analysts rating of 4.75. Therefore, it is recommended to buy TNGX.

  • StrongBuy: 6
  • Buy: 2
  • Hold: 0
  • Sell: 0
  • StrongSell: 0

What are the forecasts/targets for the TNGX price?
Analysts Target Price 31.9 47.5%
Tango Therapeutics (TNGX) - Fundamental Data Overview as of 22 May 2026
P/S = 53.8318
P/B = 7.7809
Revenue TTM = 57.0m USD
EBIT TTM = -115.4m USD
EBITDA TTM = -113.3m USD
Long Term Debt = 30.0m USD (estimated: total debt 32.8m - short term 2.83m)
Short Term Debt = 2.83m USD (from shortTermDebt, last quarter)
Debt = 32.8m USD (from shortLongTermDebtTotal, last quarter) (leases 32.8m already included)
Net Debt = -347.1m USD (calculated: Debt 32.8m - CCE 379.8m)
Enterprise Value = 2.72b USD (3.07b + Debt 32.8m - CCE 379.8m)
 Interest Coverage Ratio = unknown (Ebit TTM -115.4m / Interest Expense TTM 0.0)
 EV/FCF = -35.74x (Enterprise Value 2.72b / FCF TTM -76.1m)
FCF Yield = -2.80% (FCF TTM -76.1m / Enterprise Value 2.72b)
 FCF Margin = -133.6% (FCF TTM -76.1m / Revenue TTM 57.0m)
 Net Margin = -188.2% (Net Income TTM -107.2m / Revenue TTM 57.0m)
 Gross Margin = unknown ((Revenue TTM 57.0m - Cost of Revenue TTM 2.12m) / Revenue TTM)
 Tobins Q-Ratio = 6.24 (Enterprise Value 2.72b / Total Assets 435.8m)
Interest Expense / Debt = 0.0% (Interest Expense 0.0 / Debt 32.8m)
Taxrate = 21.0% (US default 21%)
NOPAT = -91.1m (EBIT -115.4m * (1 - 21.00%)) [loss with tax shield]
Current Ratio = 23.41 (Total Current Assets 392.3m / Total Current Liabilities 16.8m)
Debt / Equity = 0.08 (Debt 32.8m / totalStockholderEquity, last quarter 391.5m)
 Debt / EBITDA = 3.06 (negative EBITDA) (Net Debt -347.1m / EBITDA -113.3m)
 Debt / FCF = 4.56 (negative FCF - burning cash) (Net Debt -347.1m / FCF TTM -76.1m)
 Total Stockholder Equity = 258.2m (last 4 quarters mean from totalStockholderEquity)
RoA = -30.20% (Net Income -107.2m / Total Assets 435.8m)
RoE = -11.82% (Net Income TTM -107.2m / Total Stockholder Equity 906.8m)
RoCE = -12.32% (EBIT -115.4m / Capital Employed (Equity 906.8m + L.T.Debt 30.0m))
 RoIC = -51.47% (negative operating profit) (NOPAT -91.1m / Invested Capital 177.1m)
 WACC = 9.61% (E(3.07b)/V(3.10b) * Re(9.71%) + D(32.8m)/V(3.10b) * Rd(0.0%) * (1-Tc(0.21)))
Discount Rate = 9.71% (= CAPM, Blume Beta Adj.)
Shares (quarterly) Correlation: 100.00 | Cagr: 19.70%
 [DCF] Fair Price = unknown (Cash Flow -76.1m)
 EPS Correlation: N/A | EPS CAGR: N/A | SUE: -0.38 | # QB: 0
Revenue Correlation: 55.45 | Revenue CAGR: 18.74% | SUE: -0.09 | # QB: 0
EPS current Quarter (2026-06-30): EPS=-0.33 | Chg30d=+0.00% | Revisions=+0% | Analysts=11
EPS next Quarter (2026-09-30): EPS=-0.34 | Chg30d=-3.00% | Revisions=+0% | Analysts=11
EPS current Year (2026-12-31): EPS=-1.35 | Chg30d=-0.66% | Revisions=-11% | GrowthEPS=-54.8% | GrowthRev=-100.0%
EPS next Year (2027-12-31): EPS=-1.58 | Chg30d=+1.06% | Revisions=+11% | GrowthEPS=-17.5% | GrowthRev=+0.0%
[Analyst] Revisions Ratio: -11%