(VRDN) Viridian Therapeutics - Ratings and Ratios
Monoclonal Antibody, Thyroid Eye Disease, Autoimmune Disease, Clinical Trial
EPS (Earnings per Share)
Revenue
Dividends
Currently no dividends paid| Risk via 5d forecast | |
|---|---|
| Volatility | 60.1% |
| Value at Risk 5%th | 92.4% |
| Relative Tail Risk | -6.47% |
| Reward TTM | |
|---|---|
| Sharpe Ratio | 1.23 |
| Alpha | 54.31 |
| CAGR/Max DD | 0.06 |
| Character TTM | |
|---|---|
| Hurst Exponent | 0.392 |
| Beta | 0.905 |
| Beta Downside | 0.714 |
| Drawdowns 3y | |
|---|---|
| Max DD | 70.69% |
| Mean DD | 46.65% |
| Median DD | 50.16% |
Description: VRDN Viridian Therapeutics November 12, 2025
Viridian Therapeutics (NASDAQ: VRDN) is a U.S. biotech focused on monoclonal-antibody therapies for rare and serious diseases, most notably thyroid eye disease (TED). The firm originated as Miragen Therapeutics and rebranded in January 2021; it is headquartered in Waltham, Massachusetts and trades as a common-stock biotech under the GICS sub-industry “Biotechnology.”
The current pipeline centers on two IGF-1R-targeting antibodies in Phase 3: veligrotug (a conventional IgG1) and VRDN-003 (a half-life-extended, next-generation construct). Both are being evaluated for TED, a condition affecting roughly 0.25 % of the U.S. adult population and representing a $1.5 bn addressable market according to recent market-research estimates. In parallel, Viridian is advancing anti-neonatal Fc receptor (FcRn) candidates (VRDN-006, VRDN-008) aimed at broader autoimmune indications, though these remain pre-clinical.
As of the latest 10-Q (Q2 2024), the company reported cash and equivalents of $85 million and a monthly burn rate of approximately $6 million, giving it ~14 months of runway absent additional financing. The biotech sector’s capital-raising environment has tightened since 2022, making cash-runway a critical risk factor for early-stage firms. Moreover, the success of Phase 3 trials in TED would place Viridian in a niche with limited competition-current FDA-approved therapies (e.g., teprotumumab) are priced above $30,000 per course, suggesting strong pricing power if efficacy is demonstrated.
For a deeper, data-driven assessment of VRDN’s risk-adjusted upside, you may find the analytics on ValueRay useful-its platform aggregates trial-stage metrics and cash-flow forecasts that can help you quantify the potential impact of a Phase 3 readout.
Piotroski VR‑10 (Strict, 0-10) 1.0
| Net Income (-302.0m TTM) > 0 and > 6% of Revenue (6% = 4.25m TTM) |
| FCFTA -0.57 (>2.0%) and ΔFCFTA -30.97pp (YES ≥ +1.0pp, WARN ≥ +0.5pp) |
| NWC/Revenue 736.3% (prev 240.4k%; Δ -239.7kpp) (YES ≤20% & Δ≤-1pp; WARN ≤25% & Δ≤0 oder ≤40% & Δ≤-3pp) |
| CFO/TA -0.56 (>3.0%) and CFO -326.0m <= Net Income -302.0m (YES >=105%, WARN >=100%) |
| NO Net Debt/EBITDA fails (EBITDA <= 0) |
| Current Ratio 11.28 (target 1.5–3.0; WARN 1.2–<1.5 or >3.0–5.0; CFO/TA gate active) |
| Outstanding Shares last Quarter (81.8m) change vs 12m ago 23.13% (target <= -2.0% for YES) |
| Gross Margin 99.83% (prev -2048 %; Δ 2148 pp) >=18% & Δ>=+0.5pp (WARN >=15% & Δ>=0) |
| Asset Turnover 10.49% (prev 0.04%; Δ 10.46pp) >=50% & Δ>=+2pp (WARN >=35% & Δ>=0) |
| Interest Coverage Ratio -118.9 (EBITDA TTM -299.0m / Interest Expense TTM 2.52m) >= 6 (WARN >= 3) |
Altman Z'' -21.17
| (A) 0.90 = (Total Current Assets 571.9m - Total Current Liabilities 50.7m) / Total Assets 577.1m |
| (B) -2.11 = Retained Earnings (Balance) -1.22b / Total Assets 577.1m |
| warn (B) unusual magnitude: -2.11 — check mapping/units |
| (C) -0.44 = EBIT TTM -299.5m / Avg Total Assets 674.5m |
| (D) -16.41 = Book Value of Equity -1.22b / Total Liabilities 74.2m |
| Total Rating: -21.17 = (6.56 * A) + (3.26 * B) + (6.72 * C) + (1.05 * D) |
ValueRay F-Score (Strict, 0-100) 46.85
| 1. Piotroski 1.0pt |
| 2. FCF Yield -12.80% |
| 3. FCF Margin data missing |
| 4. Debt/Equity 0.05 |
| 5. Debt/Ebitda 0.49 |
| 7. RoE -52.65% |
| 8. Rev. Trend 12.25% |
| 9. EPS Trend 52.23% |
What is the price of VRDN shares?
Over the past week, the price has changed by -1.70%, over one month by +1.37%, over three months by +66.09% and over the past year by +65.07%.
Is VRDN a buy, sell or hold?
- Strong Buy: 9
- Buy: 5
- Hold: 2
- Sell: 0
- Strong Sell: 0
What are the forecasts/targets for the VRDN price?
| Issuer | Target | Up/Down from current |
|---|---|---|
| Wallstreet Target Price | 40.2 | 23.8% |
| Analysts Target Price | 40.2 | 23.8% |
| ValueRay Target Price | 35 | 7.9% |
VRDN Fundamental Data Overview December 20, 2025
P/S = 42.605
P/B = 9.6054
Beta = 0.914
Revenue TTM = 70.8m USD
EBIT TTM = -299.5m USD
EBITDA TTM = -299.0m USD
Long Term Debt = 20.9m USD (from longTermDebt, last quarter)
Short Term Debt = 730.0k USD (from shortTermDebt, last quarter)
Debt = 23.8m USD (from shortLongTermDebtTotal, last quarter)
Net Debt = -145.8m USD (from netDebt column, last quarter)
Enterprise Value = 2.55b USD (3.02b + Debt 23.8m - CCE 490.9m)
Interest Coverage Ratio = -118.9 (Ebit TTM -299.5m / Interest Expense TTM 2.52m)
FCF Yield = -12.80% (FCF TTM -326.3m / Enterprise Value 2.55b)
FCF Margin = -461.0% (FCF TTM -326.3m / Revenue TTM 70.8m)
Net Margin = -426.6% (Net Income TTM -302.0m / Revenue TTM 70.8m)
Gross Margin = 99.83% ((Revenue TTM 70.8m - Cost of Revenue TTM 123.0k) / Revenue TTM)
Gross Margin QoQ = 100.0% (prev 100.0%)
Tobins Q-Ratio = 4.42 (Enterprise Value 2.55b / Total Assets 577.1m)
Interest Expense / Debt = 2.35% (Interest Expense 560.0k / Debt 23.8m)
Taxrate = 100.0% (out of range, set to none) (-269.9m / -269.9m)
NOPAT = unknown (EBIT/Op.Income or Taxrate missing)
Current Ratio = 11.28 (Total Current Assets 571.9m / Total Current Liabilities 50.7m)
Debt / Equity = 0.05 (Debt 23.8m / totalStockholderEquity, last quarter 503.0m)
Debt / EBITDA = 0.49 (negative EBITDA) (Net Debt -145.8m / EBITDA -299.0m)
Debt / FCF = 0.45 (negative FCF - burning cash) (Net Debt -145.8m / FCF TTM -326.3m)
Total Stockholder Equity = 573.6m (last 4 quarters mean from totalStockholderEquity)
RoA = -52.32% (Net Income -302.0m / Total Assets 577.1m)
RoE = -52.65% (Net Income TTM -302.0m / Total Stockholder Equity 573.6m)
RoCE = -50.37% (EBIT -299.5m / Capital Employed (Equity 573.6m + L.T.Debt 20.9m))
RoIC = -842.6% (out of range, set to none) (EBIT -299.5m / (Assets 577.1m - Curr.Liab 50.7m - Cash 490.9m))
WACC = 9.28% (E(3.02b)/V(3.04b) * Re(9.35%) + (debt cost/tax rate unavailable))
Discount Rate = 9.35% (= CAPM, Blume Beta Adj.)
Shares Correlation 3-Years: 100.0 | Cagr: 28.30%
Fair Price DCF = unknown (Cash Flow -326.3m)
EPS Correlation: 52.23 | EPS CAGR: 39.53% | SUE: 2.68 | # QB: 1
Revenue Correlation: 12.25 | Revenue CAGR: 369.4% | SUE: 4.0 | # QB: 1
EPS next Quarter (2026-03-31): EPS=-1.13 | Chg30d=-0.030 | Revisions Net=-1 | Analysts=3
EPS next Year (2026-12-31): EPS=-3.48 | Chg30d=-0.085 | Revisions Net=+1 | Growth EPS=+0.6% | Growth Revenue=+4.5%
Additional Sources for VRDN Stock
Tweets: X | Stocktwits
Fund Manager Positions: Dataroma | Stockcircle