(XBI) SPDR S&P Biotech - Ratings and Ratios

Exchange: NYSE ARCA • Country: USA • Currency: USD • Type: Etf • ISIN: US78464A8707

Stocks, Biotech, Small-Cap, Mid-Cap, Equal-Weight

Risk via 10d forecast
Volatility 24.9%
Value at Risk 5%th 42.9%
Relative Tail Risk 2.57%
Reward TTM
Sharpe Ratio 0.46
Alpha 0.27
Character TTM
Hurst Exponent 0.321
Beta 0.925
Beta Downside 0.887
Drawdowns 3y
Max DD 32.99%
Mean DD 10.92%
Median DD 10.15%

Description: XBI SPDR S&P Biotech November 06, 2025

The SPDR S&P Biotech ETF (ticker XBI) aims to replicate the S&P Biotechnology Select Industry Index by using a sampling approach, allocating at least 80 % of its assets to the index’s constituents. The index captures the biotech segment of the broader S&P Total Market Index, providing exposure to a diversified basket of U.S. biotechnology firms.

Key quantitative details (as of the latest filing) include an expense ratio of roughly 0.35 %, about 140 holdings with a median market-cap near $2 billion, and a weighted average dividend yield close to 0 % (reflecting the sector’s growth focus). Recent performance has been driven by a surge in FDA approvals-biotech companies saw a 12 % YoY increase in new drug clearances in 2024-and robust R&D spending, which grew at an annualized 8 % rate, supporting pipeline expansion.

Macro-level drivers such as U.S. healthcare policy stability, the pace of gene-therapy commercialization, and the availability of venture capital continue to shape sector risk-reward dynamics.

For a deeper dive into XBI’s valuation metrics and risk profile, you might explore the analysis on ValueRay.

XBI ETF Overview

Market Cap in USD 6,608m
Category Health
TER 0.35%
IPO / Inception 2006-01-31
Return 12m vs S&P 500 7.26%
Analyst Rating -

XBI Dividends

Dividend Yield 0.04%
Yield on Cost 5y 0.03%
Yield CAGR 5y -17.13%
Payout Consistency 46.7%
Payout Ratio -

XBI Growth Ratios

CAGR 3y 12.26%
CAGR/Max DD Calmar Ratio 0.37
CAGR/Mean DD Pain Ratio 1.12
Current Volume 14432.7k
Average Volume 11352.6k

What is the price of XBI shares?

As of November 17, 2025, the stock is trading at USD 114.01 with a total of 14,432,700 shares traded.
Over the past week, the price has changed by +3.56%, over one month by +5.65%, over three months by +26.42% and over the past year by +24.03%.

Is SPDR S&P Biotech a good stock to buy?

Neither. Based on ValueRay´s Analyses, SPDR S&P Biotech is currently (November 2025) neither a good nor a bad stock to buy. It has a ValueRay Growth Rating of 25.79 and therefor a technical neutral rating according to historical growth.
Based on momentum, paid dividends and discounted-cash-flow analyses, the fair value of XBI is around 108.50 USD . This means that XBI is currently overvalued and has a potential downside of -4.83%.

Is XBI a buy, sell or hold?

SPDR S&P Biotech has no consensus analysts rating.

What are the forecasts/targets for the XBI price?

Issuer Target Up/Down from current
Wallstreet Target Price - -
Analysts Target Price - -
ValueRay Target Price 122 7%

XBI Fundamental Data Overview November 15, 2025

Market Cap USD = 6.61b (6.61b USD * 1.0 USD.USD)
Beta = 1.26
Revenue TTM = 0.0 USD
EBIT TTM = 0.0 USD
EBITDA TTM = 0.0 USD
Long Term Debt = unknown (none)
Short Term Debt = unknown (none)
Debt = unknown
Net Debt = unknown
Enterprise Value = 6.61b USD (6.61b + (null Debt) - (null CCE))
Interest Coverage Ratio = unknown (Ebit TTM 0.0 / Interest Expense TTM 0.0)
FCF Yield = 0.0% (FCF TTM 0.0 / Enterprise Value 6.61b)
FCF Margin = unknown (Revenue TTM is 0 or missing)
Net Margin = unknown
Gross Margin = unknown ((Revenue TTM 0.0 - Cost of Revenue TTM 0.0) / Revenue TTM)
Tobins Q-Ratio = unknown (Enterprise Value 6.61b / Total Assets none)
Interest Expense / Debt = unknown (Interest Expense 0.0 / Debt none)
Taxrate = 21.0% (US default 21%)
NOPAT = 0.0 (EBIT 0.0 * (1 - 21.00%))
Current Ratio = unknown (Total Current Assets none / Total Current Liabilities none)
Debt / Equity = unknown (Debt none)
Debt / EBITDA = unknown (Net Debt none / EBITDA 0.0)
Debt / FCF = unknown (Net Debt none / FCF TTM 0.0)
Total Stockholder Equity = 0.0 (from calculated bookValueOfEquity)
RoA = unknown (Net Income 0.0 / Total Assets none)
RoE = unknown (Net Income TTM 0.0 / Total Stockholder Equity 0.0)
RoCE = unknown (EBIT 0.0 / Capital Employed )
RoIC = unknown (NOPAT 0.0, Invested Capital 0.0, EBIT 0.0)
WACC = 9.42% (E(6.61b)/V(6.61b) * Re(9.42%) + (debt-free company))
Discount Rate = 9.42% (= CAPM, Blume Beta Adj.)
Fair Price DCF = unknown (Cash Flow 0.0)

Additional Sources for XBI ETF

News: Wall Street Journal | Benzinga | Yahoo Finance
Tweets: X | Stocktwits
Fund Manager Positions: Dataroma | Stockcircle