STRO Stock Analysis: Sutro Biopharma | NASDAQ

Biotechnology | NASDAQ, USA | Market Cap: 379m USD | 12M Return: 200.1% | Charts, Fundamentals & Technical Analysis

Antibody Conjugates, Cancer Therapies, Pneumococcal Vaccines
Total Rating 44
Safety 27
Buy Signal -0.97
Biotechnology
Industry Rotation: -21.3
Market Cap: 379M
Avg Turnover: 7.88M
Risk 3d forecast
Volatility92.7%
VaR 5th Pctl14.9%
VaR vs Median-2.58%
Reward TTM
Sharpe Ratio1.62
Rel. Str. IBD95.2
Rel. Str. Peer Group75
Character TTM
Beta1.705
Beta Downside1.858
Hurst Exponent0.535
Drawdowns 3y
Max DD90.72%
CAGR/Max DD-0.20
CAGR/Mean DD-0.35
EPS (Earnings per Share) EPS (Earnings per Share) of STRO over the last years for every Quarter: "2021-06": -1.3, "2021-09": -6.7, "2021-12": -0.83, "2022-03": -8.4, "2022-06": -5.5, "2022-09": -3.7, "2022-12": -8.18, "2023-03": -0.85, "2023-06": -7.69, "2023-09": -8.1, "2023-12": 0.52, "2024-03": -8.9, "2024-06": -5.61, "2024-09": -5.9, "2024-12": -0.6332, "2025-03": -9.1, "2025-06": -0.14, "2025-09": -5.57, "2025-12": -5.4474, "2026-03": -2.94,
Last SUE: 0.10
Qual. Beats: 0
Revenue Revenue of STRO over the last years for every Quarter: 2021-06: 28.049, 2021-09: 8.517, 2021-12: 10.654, 2022-03: 5.897, 2022-06: 28.096, 2022-09: 25.147, 2022-12: 8.632, 2023-03: 12.674, 2023-06: 10.412, 2023-09: 16.924, 2023-12: 113.721, 2024-03: 13.008, 2024-06: 25.706, 2024-09: 8.52, 2024-12: 14.809, 2025-03: 17.399, 2025-06: 63.745, 2025-09: 9.693, 2025-12: 11.647, 2026-03: 14.523,
Rev. CAGR: 6.56%
Rev. Trend: 13.1%
Last SUE: 0.41
Qual. Beats: 0

Warnings

Negative Equity With Losses
Strong Share Dilution
Interest Coverage Ratio Critical
Altman Z'' In Financial Distress Zone

Tailwinds

Seasonal Tailwind
Rs Leader

Seasonality 7.8 years of data

Jan +0.2% 9
Feb -4.3% 23
Mar +1.9% 21
Apr -5.3% 21
May +1.6% 9
Jun -3.4% 22
Jul +0.4% 9
Aug +18.4% 60
Sep +0.1% 6
Oct +11.2% 22
Nov +1.4% 6
Dec +10.8% 10

How good or bad each month usually is (without trend). The score below shows how much you can trust it: 0 = pure chance, >40 gets interesting and >55 is strong.

Description: STRO Sutro Biopharma

Sutro Biopharma is a clinical-stage oncology company headquartered in South San Francisco that develops antibody drug conjugates (ADCs) using its proprietary cell-free protein synthesis platforms, XpressCF and XpressCF+. Its lead candidate, STRO-004, targets tissue factor (TF) for the treatment of multiple TF-expressing solid tumors, including non-small cell lung, head and neck squamous cell, cervical, colorectal, pancreatic, endometrial, and bladder cancers. The pipeline also includes STRO-003, a ROR1-directed ADC for solid and hematological cancers, and pneumococcal conjugate vaccine candidates (VAX-24 and VAX-31) developed with partner Vaxcyte, which are in Phase II/III clinical trials.

Sutro generates revenue primarily through research collaborations and licensing agreements rather than commercial product sales, with notable partners including Tasly Biopharmaceuticals (Greater China rights to STRO-002), Ipsen (STRO-003), and Astellas Pharma (immunostimulatory ADCs). Founded in 2003 and formerly known as Fundamental Applied Biology, the company went public on NASDAQ in September 2018. As a small-cap biotechnology firm, Sutros business model is characteristic of the pre-commercial biotech sector, where value is driven by pipeline progress, clinical trial readouts, and partnership milestones rather than recurring product revenue.

Headlines to Watch Out For
  • STRO-002 luvelta Phase 2 ovarian cancer data readout
  • Vaxcyte collaboration milestones supplement limited product revenue
  • ADC competition from Daiichi AstraZeneca pressures pipeline valuation
Piotroski VR-10 (Strict) 2.0
Net Income: -153.6m TTM > 0 and > 6% of Revenue
FCF/TA: -0.57 > 0.02 and ΔFCF/TA 10.90 > 1.0
NWC/Revenue: 150.8% < 20% (prev 232.4%; Δ -81.60% < -1%)
CFO/TA -0.63 > 3% & CFO -151.6m > Net Income -153.6m
Net Debt/EBITDA: error (EBITDA <= 0)
Current Ratio: 3.12 > 1.5 & < 3
Outstanding Shares: last quarter (13.1m) vs 12m ago 57.42% < -2%
Gross Margin: 93.27% > 18% (prev 89.14%; Δ 4.14% > 0.5%)
Asset Turnover: 35.36% > 50% (prev 20.67%; Δ 14.69% > 0%)
Interest Coverage Ratio: -2.83 > 6 (EBIT TTM -112.8m / Interest Expense TTM 39.9m)
Altman Z'' -12.54
A: 0.62 (Total Current Assets 221.0m - Total Current Liabilities 70.8m) / Total Assets 242.0m
B: -4.20 (Retained Earnings -1.02b / Total Assets 242.0m)
C: -0.40 (EBIT TTM -112.8m / Avg Total Assets 281.7m)
D: -0.22 (Book Value of Equity -66.9m / Total Liabilities 308.9m)
Altman-Z'' = -12.54 = D
Beneish M -1.99
DSRI: 0.61 (Receivables 12.5m/13.6m, Revenue 99.6m/66.4m)
GMI: 0.96 (GM 89.14% / 93.27%)
AQI: 2.74 (AQ_t 0.01 / AQ_t-1 0.00)
SGI: 1.50 (Revenue 99.6m / 66.4m)
TATA: -0.01 (NI -153.6m - CFO -151.6m) / TA 242.0m)
Beneish M = -1.99 (Cap -4..+1) = B
What is the price of STRO shares?

As of August 02, 2026, the stock is trading at USD 24.17 with a total of 163,209 shares traded. Over the past week, the price has changed by +5.64%, over one month by -27.20%, over three months by -34.00% and over the past year by +200.14%.

Current recommended Stop Loss: 21.60 (which is 10.6% or 1.3 ATR below the current price).

Is STRO a buy, sell or hold?

Sutro Biopharma has received a consensus analysts rating of 3.70. Therefore, it is recommended to hold STRO.

  • StrongBuy: 4
  • Buy: 0
  • Hold: 5
  • Sell: 1
  • StrongSell: 0

What are the forecasts/targets for the STRO price?
Analysts Target Price 47.8 97.6%
Sutro Biopharma (STRO) - Fundamental Data Overview as of 27 July 2026
Market Cap USD = 379.1m (379.1m USD * 1.0 USD.USD)
P/E Forward = 10.0301
P/S = 3.8062
P/B = 2.1114
Revenue TTM = 99.6m USD
EBIT TTM = -112.8m USD
EBITDA TTM = -106.1m USD
Long Term Debt = 6.03m USD (estimated: total debt 13.6m - short term 7.60m)
Short Term Debt = 7.60m USD (from shortTermDebt, last quarter)
Debt = 13.6m USD (from shortLongTermDebtTotal, last quarter) (leases 13.6m already included)
Net Debt = -188.9m USD (calculated: Debt 13.6m - CCE 202.6m)
Enterprise Value = 190.2m USD (379.1m + Debt 13.6m - CCE 202.6m)
Interest Coverage Ratio = -2.83 (Ebit TTM -112.8m / Interest Expense TTM 39.9m)
EV/FCF = -1.38x (Enterprise Value 190.2m / FCF TTM -137.4m)
FCF Yield = -72.24% (FCF TTM -137.4m / Enterprise Value 190.2m)
 FCF Margin = -137.9% (FCF TTM -137.4m / Revenue TTM 99.6m)
 Net Margin = -154.2% (Net Income TTM -153.6m / Revenue TTM 99.6m)
Gross Margin = 93.27% ((Revenue TTM 99.6m - Cost of Revenue TTM 6.70m) / Revenue TTM)
Gross Margin QoQ = 91.20% (prev 86.06%)
Tobins Q-Ratio = 0.79 (Enterprise Value 190.2m / Total Assets 242.0m)
 Interest Expense / Debt = 292.3% (Interest Expense 39.9m / Debt 13.6m)
 Taxrate = 21.0% (US federal default 21%)
NOPAT = -89.1m (EBIT -112.8m * (1 - 21.00%)) [loss with tax shield]
Current Ratio = 2.90 (Total Current Assets 221.0m / Total Current Liabilities 76.3m)
 Debt / Equity = -0.20 (negative equity) (Debt 13.6m / totalStockholderEquity, last quarter -66.9m)
 Debt / EBITDA = 1.78 (negative EBITDA) (Net Debt -188.9m / EBITDA -106.1m)
 Debt / FCF = 1.38 (negative FCF - burning cash) (Net Debt -188.9m / FCF TTM -137.4m)
 Total Stockholder Equity = -79.7m (last 4 quarters mean from totalStockholderEquity)
RoA = -54.53% (Net Income -153.6m / Total Assets 242.0m)
 RoE = 192.8% (negative equity) (Net Income TTM -153.6m / Total Stockholder Equity -79.7m)
 RoCE = 153.2% (negative capital employed) (EBIT -112.8m / Capital Employed (Equity -79.7m + L.T.Debt 6.03m))
 RoIC = -51.28% (negative operating profit) (NOPAT -89.1m / Invested Capital 173.8m)
 WACC = 11.56% (E(379.1m)/V(392.8m) * Re(11.98%) + (debt cost/tax rate unavailable))
Discount Rate = 11.98% (= CAPM, Blume Beta Adj.)
Shares (quarterly) Correlation: 79.74 | Cagr: 40.36%
 [DCF] Fair Price = unknown (Cash Flow -137.4m)
 EPS Correlation: N/A | EPS CAGR: N/A | SUE: 0.10 | # QB: 0
Revenue Correlation: 13.08 | Revenue CAGR: 6.56% | SUE: 0.41 | # QB: 0
EPS current Quarter (2026-06-30): EPS=-2.39 | Chg30d=N/A | Revisions=+0% | Analysts=3
EPS next Quarter (2026-09-30): EPS=-2.46 | Chg30d=N/A | Revisions=+0% | Analysts=3
EPS current Year (2026-12-31): EPS=-7.80 | Chg30d=-16.29% | Revisions=-25% | GrowthEPS=+51.8% | GrowthRev=-56.5%
EPS next Year (2027-12-31): EPS=-6.88 | Chg30d=-177.62% | Revisions=-25% | GrowthEPS=+11.8% | GrowthRev=-29.2%
[Analyst] Revisions Ratio: -40% (up=0, down=2)