(XBI) S&P Biotech - Overview

ETF Category: Health | Exchange: NYSE (USA) | Market Cap: 8.150m USD | Total Return: 53.3% in 12m

Biotechnology, Pharmaceuticals, Gene Therapy, Life Sciences
Total Rating 82
Safety 64
Buy Signal -0.26
Health
Category Rotation: +12.5
TER: 0.35%
AUM: 8.15B
Avg Turnover: 1.02B
Risk 3d forecast
Volatility34.9%
VaR 5th Pctl6.34%
VaR vs Median0.97%
Reward TTM
Sharpe Ratio1.70
Rel. Str. IBD71.8
Rel. Str. Peer Group90.5
Character TTM
Beta0.908
Beta Downside0.830
Hurst Exponent0.326
Drawdowns 3y
Max DD32.99%
CAGR/Max DD0.42
CAGR/Mean DD1.43

Warnings

No concerns identified

Tailwinds

No distinct edge detected

Description: XBI S&P Biotech

The SPDR S&P Biotech ETF (XBI) tracks the S&P Biotechnology Select Industry Index, utilizing a sampling strategy to replicate the performance of the biotechnology segment within the broader S&P Total Market Index. The fund maintains a policy of investing at least 80% of its total assets in the constituent securities of its benchmark index. Unlike many market-cap-weighted funds, this ETF follows an equal-weighted methodology, which provides higher exposure to small and mid-cap companies within the sector.

The biotechnology sector is characterized by high research and development (R&D) intensity and a business model often reliant on the clinical trial success of proprietary drug candidates. Companies in this space frequently engage in strategic partnerships or acquisitions with larger pharmaceutical firms to fund late-stage development and commercialization. Investors can utilize ValueRay to further analyze the underlying holdings and valuation metrics of this ETF. Established in 2006, XBI serves as a primary benchmark for liquid exposure to the U.S. biotech industry.

Headlines to Watch Out For
  • Interest rate cuts drive capital flows into small-cap biotech
  • M&A activity increases as pharmaceutical giants face patent cliffs
  • FDA drug approval rates influence speculative clinical-stage valuations
  • Funding environment improves as venture capital and secondary offerings stabilize
What is the price of XBI shares?

As of June 08, 2026, the stock is trading at USD 128.67 with a total of 8,385,179 shares traded.
Over the past week, the price has changed by -5.87%, over one month by -3.73%, over three months by +1.22% and over the past year by +53.25%.

Is XBI a buy, sell or hold?

S&P Biotech has no consensus analysts rating.