XBI ETF Analysis: S&P Biotech | NYSE

Healthcare Equity | NYSE, USA | Market Cap: 10.311m USD | 12M Return: 41.5% | US78464A8707 | Charts, Fundamentals & Technical Analysis

Biotechnology, Pharmaceuticals, Drug Development, Medical Research
Total Rating 63
Safety 64
Buy Signal -0.04
Healthcare Equity
Category Rotation: +2.5
TER: 0.33%
AUM: 10.3B
Avg Turnover: 1.42B
Risk 3d forecast
Volatility36.9%
VaR 5th Pctl6.79%
VaR vs Median2.08%
Reward TTM
Sharpe Ratio1.17
Rel. Str. IBD78
Rel. Str. Peer Group16.7 pctl
Character TTM
Beta0.849
Beta Downside0.725
Hurst Exponent0.532
Choppyness67.3%
Drawdowns 3y
Max DD32.99%
CAGR/Max DD0.92
CAGR/Mean DD3.74

Warnings

No concerns identified

Tailwinds

No distinct edge detected

Seasonality 11.7 years of data

Jan +0.4% 5
Feb -0.7% 8
Mar -4.5% 34
Apr -1.0% 18
May +0.4% 7
Jun +4.7% 34
Jul -0.2% 14
Aug +2.0% 19
Sep -2.1% 31
Oct -2.8% 24
Nov +4.8% 40
Dec -0.4% 34

How good or bad each month usually is (without trend). The score below shows how much you can trust it: 0 = pure chance, >40 gets interesting and >55 is strong.

Description: XBI S&P Biotech

The SPDR S&P Biotech ETF (XBI) is an exchange-traded fund that seeks to track the performance of the S&P Biotechnology Select Industry Index. The fund employs a sampling strategy, investing at least 80% of its total assets in securities comprising the underlying index, which represents the biotechnology segment of the broader S&P Total Market Index.

Launched in January 2006 and classified within the Health category, XBI provides U.S. market exposure to large-cap biotechnology companies. The biotechnology sector generally includes firms engaged in the research, development, and commercialization of therapies, vaccines, and diagnostic technologies, with business models typically driven by product pipelines, clinical trial outcomes, and regulatory approvals from agencies such as the U.S. Food and Drug Administration (FDA).

Headlines to Watch Out For
  • FDA approval pipeline catalysts lift biotech index returns
  • IRA Medicare drug price negotiations pressure biotech margins
  • Fed rate cuts boost high-duration biotech valuations
What is the price of XBI shares?

As of November 11, 2026, the stock is trading at USD 155.06 with a total of 6,990,338 shares traded. Over the past week, the price has changed by +0.06%, over one month by +2.42%, over three months by -1.88% and over the past year by +41.45%.

Current recommended Stop Loss: 148.20 (which is 4.4% or 1.3 ATR below the current price).

Is XBI a buy, sell or hold?

S&P Biotech has no consensus analysts rating.