IONS Performance: 169.6% Return (12 Months)

IONS returned 169.6% over 12 months, outperforming the S&P 500 (32.1%). Volatility: 37.4%.

RS IBD 35.73
Top 41% in Peers
Volatility 37.4%
Top 10% in Peers
Total Return 12m 169.60%
Top 29% in Peers
RS Rating 88.36
Top 41% in Peers
P/E
P/E Trailing 0.00
P/E Forward 96.2
High / Low 52w
52 Week High 86.50 USD
52 Week Low 25.51 USD
Sentiment
VRO Trend Strength ±100 23.11
Buy Signal ±3 0.04
Drawdowns 3y
Max Drawdown 52.36%
Mean Drawdown 15.98%
Compare performance with 200 peers in Biotechnology
12m Total Return: IONS (169.6%) vs PEER ETF Total Return of Ionis Pharmaceuticals versus broad market ETF SPY
5y Drawdown (Underwater) Chart 5 Year Drawdown / Underwater Chart for IONS Performance: 169.6% Return (12 Months)

Top Performer in Biotechnology (5/200)

Short Term Performance
SYMBOL 1W 1M 3M
ERAS 14.59% 10.67% 371.63%
DNTH 7.61% 31.13% 136.19%
ORKA 23.84% 70.97% 111.76%
CNTA 43.84% 52.87% 74.91%
KOD 15.86% 56.88% 55.69%
IONS 2.50% 0.39% -8.79%
Long Term Performance
SYMBOL 6M 12M 5Y
ABVX 37.84% 2184.32% 929.91%
ABVX 33.07% 1990.72% 407.51%
KOD 166.21% 1688.99% -64.63%
TNGX 167.68% 1497.64% 78.77%
ERAS 634.76% 1297.55% -1.78%
IONS 7.69% 169.60% 74.12%
Overall Best Picks of Peer Group (GARP Metrics)
SYMBOL MCAP 1M 12M 5Y P/E P/E fwd PEG EPS stab EPS cagr
ROIV NASDAQ
Roivant Sciences		 20.3B -3.13% 201% 184% - - - 37.2% -14.4%
UTHR NASDAQ
United Therapeutics		 24.8B 17.0% 91.8% 179% 20.3 20.0 2.25 -2.20% -35.9%
DAWN NASDAQ
Day One Biopharmaceuticals		 2.22B 1.23% 206% -17.1% - - - 57.3% 49.0%
FOLD NASDAQ
Amicus Therapeutics		 4.53B 0.77% 102% 55.9% - 30.5 -0.18 83.6% 131%
GLUE NASDAQ
Monte Rosa Therapeutics		 1.37B -4.89% 318% -20.1% - 10.9 - 59.8% 43.8%
MIRM NASDAQ
Mirum Pharmaceuticals		 5.68B 11.5% 135% 403% - - - 84.0% 24.5%
KRYS NASDAQ
Krystal Biotech		 7.57B 3.20% 57.7% 254% 37.9 44.8 - 84.4% 26.5%
AUPH NASDAQ
Aurinia Pharmaceuticals		 2.08B 11.7% 111% 23.5% 7.54 22.7 - 63.8% 123%
STRO NASDAQ
Sutro Biopharma		 394M -5.30% 234% -88.7% - 8.96 - -29.4% -68.0%
PHARM AS
Pharming		 1.17B 7.74% 102% 28.1% - 100 - -4.20% -

Performance: IONS vs S&P 500

Total Return vs S&P 500
PERIOD IONS S&P 500 DIFFERENCE
1 Month 0.39% -1.73% 2.16%
3 Months -8.79% -4.49% -4.50%
6 Months 7.69% -1.33% 9.14%
12 Months 169.60% 32.14% 104.03%
5 Years 74.12% 72.70% 0.82%

IONS Performance FAQ

Does IONS outperform the market?

Yes, IONS significantly outperforms the market. Over the past 12 months, IONS returned 169.60% compared to 32.14% for the S&P 500.

What is the IONS return over the last 12 months?

IONS has returned 169.60% over the past 12 months, including dividends. Over 3 months the return was -8.79%, and over 5 years 74.12%.

How risky is IONS?

IONS has relatively low risk with a maximum drawdown of 52.36% over the past 3 years. The average drawdown is 15.98%.

IONS vs Sectors (12m)

Sorted by outperformance. Positive = IONS beats sector.

Relative Performance vs S&P Sectors
SECTOR ETF DIFFERENCE 12M
Consumer Staples XLP 160.1%
Health Care XLV 158.9%
Real Estate XLRE 155.9%
Financials XLF 154.7%
Consumer Discretionary XLY 147.9%
Consumer Discretionary XLY 147.9%
Communication Services XLC 140.1%
Materials XLB 136%
Industrials XLI 127.5%
Technology XLK 119.6%
Energy XLE 112.2%

IONS vs Asset Classes (12m)

Relative Performance vs Major Asset Classes
ASSET CLASS ETF DIFFERENCE 12M
S&P 500 SPY 104.03%
Gold GLD 113.4%
Long-Term Bonds TLT 169%